Phosphate regulation of biosynthesis of extracellular RNases of endospore-forming bacteria.

Abstract:

:The gene for the extracellular ribonuclease of B. pumilus KMM62 (RNase Bp) has been cloned and sequenced. The structural gene for this enzyme is similar to those of the extracellular ribonucleases of B. intermedius 7P (binase) and B. amyloliquefaciens H2 (barnase), as are the regulatory regions of binase and RNase Bp. The regulatory region of the barnase gene, however, is quite different from the other two. In the promoter of the genes for binase and RNase Bp, but not in that for barnase, is a region similar to the Pho box of E. coli. We have established that inorganic phosphate suppresses the synthesis of the binase and RNase Bp, but does not effect the synthesis of barnase.

journal_name

FEBS Lett

journal_title

FEBS letters

authors

Znamenskaya LV,Gabdrakhmanova LA,Chernokalskaya EB,Leshchinskaya IB,Hartley RW

doi

10.1016/0014-5793(94)01316-s

subject

Has Abstract

pub_date

1995-01-02 00:00:00

pages

16-8

issue

1

eissn

0014-5793

issn

1873-3468

pii

0014-5793(94)01316-S

journal_volume

357

pub_type

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