Major histocompatibility complex class I genes of the coelacanth Latimeria chalumnae.

abstract：:Syringomycin, a peptide toxin and a virulence factor produced by the bacterial phytopathogen Pseudomonas syringae pv. syringae, stimulated the phosphorylation of several plasma membrane polypeptides of red beet storage tissue. Among these was a 100-kDa polypeptide, which corresponds in size to the proton pump ATPase. ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bidwai AP,Takemoto JY

更新日期：1987-10-01 00:00:00

abstract：:Genomic imprinting results in the differential expression of genes, depending on which allele is inherited from the mother and which from the father. The effects of such differential gene expression are reflected in phenotypic differences between the reciprocal heterozygotes (Aa vs. aA). Although many imprinted genes ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cheverud JM,Hager R,Roseman C,Fawcett G,Wang B,Wolf JB

更新日期：2008-03-18 00:00:00

abstract：:In many naturally occurring habitats, bacteria live in micrometer-size confined spaces. Although bacterial growth and motility in such constrictions is of great interest to fields as varied as soil microbiology, water purification, and biomedical research, quantitative studies of the effects of confinement on bacteria...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Männik J,Driessen R,Galajda P,Keymer JE,Dekker C

更新日期：2009-09-01 00:00:00

abstract：:Microorganisms modify rates and mechanisms of chemical and physical weathering and clay growth, thus playing fundamental roles in soil and sediment formation. Because processes in soils are inherently complex and difficult to study, we employ a model based on the lichen-mineral system to identify the fundamental inter...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Banfield JF,Barker WW,Welch SA,Taunton A

更新日期：1999-03-30 00:00:00

abstract：:Saccades are rapid eye movements that orient the visual axis toward objects of interest to allow their processing by the central, high-acuity retina. Our ability to collect visual information efficiently relies on saccadic accuracy, which is limited by a combination of uncertainty in the location of the target and mot...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lisi M,Solomon JA,Morgan MJ

更新日期：2019-08-06 00:00:00

abstract：:A complementarity-determining region (CDR) of the mouse monoclonal antibody (mAb) F58 was constructed with specificity to a neutralization-inducing region of human immunodeficiency virus type 1 (HIV-1). The mAb has its major reactivity to the amino acid sequence I--GPGRA in the V3 viral envelope region. All CDRs inclu...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Levi M,Sällberg M,Rudén U,Herlyn D,Maruyama H,Wigzell H,Marks J,Wahren B

更新日期：1993-05-15 00:00:00

abstract：:Highly multiplexed assays using antibody coated, fluorescent (xMap) beads are widely used to measure quantities of soluble analytes, such as cytokines and antibodies in clinical and other studies. Current analyses of these assays use methods based on standard curves that have limitations in detecting low or high abund...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Won JH,Goldberger O,Shen-Orr SS,Davis MM,Olshen RA

更新日期：2012-02-21 00:00:00

abstract：:Membrane-associated and periplasmic proteins of Agrobacterium tumefaciens C-58 were compared with those from avirulent (nontumrigenic) derivative strains by slab and two-dimensional gel electrophoresis. Two proteins (Per-I and Per-2), with a molecular weight of 37,500 and 37,300, respectively, were detected in the sup...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sonoki S,Kado CI

更新日期：1978-08-01 00:00:00

abstract：:One mechanism of silver resistance in microorganisms is accumulation of the metal ions in the cell. Here, we report on the phenomenon of biosynthesis of silver-based single crystals with well-defined compositions and shapes, such as equilateral triangles and hexagons, in Pseudomonas stutzeri AG259. The crystals were u...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Klaus T,Joerger R,Olsson E,Granqvist CG

更新日期：1999-11-23 00:00:00

abstract：:The interaction of configurations, including all possible singly excited configurations, is incorporated into the calculation of oscillatory and rotatory intensities of simple nonplanar pi-electronic systems such as skewed butadiene and acrolein. The results are discussed in terms of the reliability of the (self-consi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cheong KK,Oshita A,Caldwell DJ,Eyring H

更新日期：1970-12-01 00:00:00

abstract：:Double-stranded RNA (dsRNA) recently has been shown to give rise to genetic interference in Caenorhabditis elegans and also is likely to be the basis for phenotypic cosuppression in plants in certain instances. While constructing a plasmid vector for transfection of trypanosome cells, we serendipitously discovered tha...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ngô H,Tschudi C,Gull K,Ullu E

更新日期：1998-12-08 00:00:00

abstract：:CD28 is a 44-kDa glycoprotein expressed as a homodimer on the surface of a major subset of human T cells. Previous studies have demonstrated that the binding of monoclonal antibodies to the CD28 surface antigen can augment the proliferation of purified human T cells stimulated with suboptimal doses of mitogens or anti...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Thompson CB,Lindsten T,Ledbetter JA,Kunkel SL,Young HA,Emerson SG,Leiden JM,June CH

更新日期：1989-02-01 00:00:00

abstract：:We modeled the behavior of recessive mutations with deleterious effects to either the sporophyte or the gametophyte, or both, in polysomic tetraploid populations by allowing for varying levels of double reduction, mutation, and self-fertilization. Double reduction causes a decrease of the equilibrium frequencies of de...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Butruille DV,Boiteux LS

更新日期：2000-06-06 00:00:00

abstract：:Conventional digital computers can execute advanced operations by a sequence of elementary Boolean functions of 2 or more bits. As a result, complicated tasks such as solving a linear system or solving a differential equation require a large number of computing steps and an extensive use of memory units to store indiv...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sun Z,Pedretti G,Ambrosi E,Bricalli A,Wang W,Ielmini D

更新日期：2019-03-05 00:00:00

abstract：:The c-rings of ATP synthases consist of individual c-subunits, all of which harbor a conserved motif of repetitive glycine residues (GxGxGxG) important for tight transmembrane α-helix packing. The c-ring stoichiometry determines the number of ions transferred during enzyme operation and has a direct impact on the ion-...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Preiss L,Klyszejko AL,Hicks DB,Liu J,Fackelmayer OJ,Yildiz Ö,Krulwich TA,Meier T

更新日期：2013-05-07 00:00:00

abstract：:B-1a cells, an anatomically, phenotypically, and functionally distinct subset of B cells that produce the bulk of natural serum IgM and much of gut-associated IgA, are an important component of the early response to pathogens. Because the induced expression of CD5, a hallmark of B-1a cells, requires a nuclear factor o...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Berland R,Wortis HH

更新日期：2003-11-11 00:00:00

abstract：:Angiogenin, a potent inducer of neovascularization in the chicken chorioallantoic membrane and rabbit cornea, promotes endothelial cell invasion of Matrigel basement membrane. A transformed bovine aortic endothelial cell line, GM 7373, is 5 times more invasive when cultured in the presence of 1 microgram of bovine ang...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hu G,Riordan JF,Vallee BL

更新日期：1994-12-06 00:00:00

abstract：:Theory predicts that double-core-hole (DCH) spectroscopy can provide a new powerful means of differentiating between similar chemical systems with a sensitivity not hitherto possible. Although DCH ionization on a single site in molecules was recently measured with double- and single-photon absorption, double-core hole...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Berrah N,Fang L,Murphy B,Osipov T,Ueda K,Kukk E,Feifel R,van der Meulen P,Salen P,Schmidt HT,Thomas RD,Larsson M,Richter R,Prince KC,Bozek JD,Bostedt C,Wada S,Piancastelli MN,Tashiro M,Ehara M

更新日期：2011-10-11 00:00:00

abstract：:Morphogenesis during human development relies on the interplay between physiochemical cues that are mediated in part by cellular density and cytoskeletal tension. Here, we interrogated these factors on vascular lineage specification during human-induced pluripotent stem-cell (hiPSC) fate decision. We found that indepe...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Smith Q,Rochman N,Carmo AM,Vig D,Chan XY,Sun S,Gerecht S

更新日期：2018-08-07 00:00:00

abstract：:Although Wingless (Wg)/Wnt signaling has been implicated in heart development of multiple organisms, conflicting results have been reported regarding the role of Wnt/beta-catenin pathway in cardiac myogenesis: Wg/armadillo signaling promotes heart development in Drosophila, whereas activation of Wnt/beta-catenin signa...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Naito AT,Shiojima I,Akazawa H,Hidaka K,Morisaki T,Kikuchi A,Komuro I

更新日期：2006-12-26 00:00:00

abstract：:Parathyroid cells have unusual responses to an increase in the external calcium concentration--a reduction in secretion and a depolarization. In an attempt to explain this behavior, we have studied voltage-clamped inside-out patches from bovine parathyroid cells. We found a potassium-selective channel that requires in...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Jia M,Ehrenstein G,Iwasa K

更新日期：1988-10-01 00:00:00

abstract：:It has been widely reported that intrinsic brain activity, in a variety of animals including humans, is spatiotemporally structured. Specifically, propagated slow activity has been repeatedly demonstrated in animals. In human resting-state fMRI, spontaneous activity has been understood predominantly in terms of zero-l...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Mitra A,Snyder AZ,Blazey T,Raichle ME

更新日期：2015-04-28 00:00:00

abstract：:The T helper type 2 (Th2) cytokine genes Il4, Il5, and Il13 are contained within a 140-kb region of mouse chromosome 11 and their expression is controlled by a locus control region (LCR) embedded within this locus. The LCR is composed of a number of DNase I-hypersensitive sites (HSs), which are believed to encompass t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Williams A,Lee GR,Spilianakis CG,Hwang SS,Eisenbarth SC,Flavell RA

更新日期：2013-04-23 00:00:00

abstract：:Classical hypotheses regarding the evolutionary origin of paired appendages propose transformation of precursor structures (gill arches and lateral fin folds) into paired fins. During development, gnathostome paired appendages form as outgrowths of body wall somatopleure, a tissue composed of somatic lateral plate mes...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Tulenko FJ,McCauley DW,Mackenzie EL,Mazan S,Kuratani S,Sugahara F,Kusakabe R,Burke AC

更新日期：2013-07-16 00:00:00

abstract：:Once-abundant aerial insectivores, such as the Tree Swallow (Tachycineta bicolor), have declined steadily in the past several decades, making it imperative to understand all aspects of their ecology. Aerial insectivores forage on a mixture of aquatic and terrestrial insects that differ in fatty acid composition, speci...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Twining CW,Brenna JT,Lawrence P,Shipley JR,Tollefson TN,Winkler DW

更新日期：2016-09-27 00:00:00

abstract：:Biotrophic plant pathogenic fungi differentiate specialized infection structures within the living cells of their host plants. These haustoria have been linked to nutrient uptake ever since their discovery. We have for the first time to our knowledge shown that the flow of sugars from the host Vicia faba to the rust f...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Voegele RT,Struck C,Hahn M,Mendgen K

更新日期：2001-07-03 00:00:00

abstract：:The neutrality theory predicts that the rate of neutral molecular evolution is constant over time, and thus that there is a molecular clock for timing evolutionary events. It has been observed that the variance of the rate of evolution is generally larger than expected according to the neutrality theory, which has rai...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Rodríguez-Trelles F,Tarrío R,Ayala FJ

更新日期：2001-09-25 00:00:00

abstract：:The simple yet powerful technique of induced pluripotency may eventually supply a wide range of differentiated cells for cell therapy and drug development. However, making the appropriate cells via induced pluripotent stem cells (iPSCs) requires reprogramming of somatic cells and subsequent redifferentiation. Given ho...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kim J,Efe JA,Zhu S,Talantova M,Yuan X,Wang S,Lipton SA,Zhang K,Ding S

更新日期：2011-05-10 00:00:00

abstract：:Native cytochrome c (cyt c) has a compact tertiary structure with a hexacoordinated heme iron and functions in electron transport in mitochondria and apoptosis in the cytoplasm. However, the possibility that protein modifications confer additional functions to cyt c has not been explored. Disruption of methionine 80 (...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Godoy LC,Muñoz-Pinedo C,Castro L,Cardaci S,Schonhoff CM,King M,Tórtora V,Marín M,Miao Q,Jiang JF,Kapralov A,Jemmerson R,Silkstone GG,Patel JN,Evans JE,Wilson MT,Green DR,Kagan VE,Radi R,Mannick JB

更新日期：2009-02-24 00:00:00

abstract：:Maize domestication is one of the greatest feats of artificial selection and evolution, wherein a weedy plant in Central Mexico was converted through human-mediated selection into the most productive crop in the world. In fact, the changes were so astounding that it took much of the last century to identify modern mai...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Tian F,Stevens NM,Buckler ES 4th

更新日期：2009-06-16 00:00:00