Short-term plasticity in turtle dorsal horn neurons mediated by L-type Ca2+ channels.

abstract：:Neurofibrillary tangles in Alzheimer's disease are composed of hyperphosphorylated forms of the microtubule-associated protein tau. Based on biochemical criteria, several enzymes have emerged as potential tau protein kinases, including the extracellularly regulated kinases 1, 2 and 3. In situ hybridization was used to...

journal_title：Neuroscience

authors： Hollister RD,Page KJ,Hyman BT

更新日期：1997-08-01 00:00:00

abstract：:Dopaminergic compounds often affect the unlearned behaviors of preweanling and adult rats differently, although the brain regions underlying these age-dependent behavioral effects have not been specified. A candidate brain region is the dorsal caudate-putamen (CPu); thus, a goal of the present study was to determine w...

journal_title：Neuroscience

authors： Charntikov S,Der-Ghazarian T,Herbert MS,Horn LR,Widarma CB,Gutierrez A,Varela FA,McDougall SA

更新日期：2011-06-02 00:00:00

abstract：:While chronic pain is a main symptom in endometriosis, the underlying mechanisms and effective therapy remain elusive. We developed an animal model enabling the exploration of ectopic endometrium as a source of endometriosis pain. Rats were surgically implanted with autologous uterus in the gastrocnemius muscle. Withi...

journal_title：Neuroscience

authors： Alvarez P,Chen X,Hendrich J,Irwin JC,Green PG,Giudice LC,Levine JD

更新日期：2012-12-06 00:00:00

abstract：:The efferent connections of the thalamic nucleus dorsointermedius posterior were studied in the pigeon. In pigeons, this thalamic nucleus receives both paleostriatal (basal ganglia) and cerebellar input and has been compared to nuclei of the mammalian thalamic ventral tier on this basis. The present results show that ...

journal_title：Neuroscience

authors： Kitt CA,Brauth SE

更新日期：1982-01-01 00:00:00

abstract：:Neuropathic pain resulting from spinal cord injury is often accompanied by maladaptive plasticity of the central nervous system, including the opioid receptor-rich periaqueductal gray (PAG). Evidence suggests that sensory signaling via the PAG is robustly modulated by dopamine D1- and D2-like receptors, but the effect...

journal_title：Neuroscience

authors： Voulalas PJ,Ji Y,Jiang L,Asgar J,Ro JY,Masri R

更新日期：2017-02-20 00:00:00

abstract：:The release of chemical transmitter from nerve terminals is critically dependent on a transient increase in intracellular Ca2+. The increase in Ca2+ may be due to influx of Ca2+ from the extracellular fluid or release of Ca2+ from intracellular stores such as mitochondria. Whether Ca2+ utilized in transmitter release ...

journal_title：Neuroscience

authors： Brailoiu E,Miyamoto MD

更新日期：2000-01-01 00:00:00

abstract：:Synapse specific differences in NR2 subunit expression exist in several systems within the mammalian CNS. Here we have studied such differences on motoneurons in the neonatal rat cord using ifenprodil known to inhibit voltage-, use- and glycine-independent responses mediated by NR2B-containing N-methyl-d-aspartate rec...

journal_title：Neuroscience

authors： Shanthanelson M,Mendell LM

更新日期：2010-03-17 00:00:00

abstract：:Stress plays a pivotal role in the development and/or exacerbation of functional gastrointestinal (GI) disorders. The paraventricular nucleus of the hypothalamus (PVN) contains neurons that are part of the hypothalamic-pituitary-adrenal axis as well as preautonomic neurons innervating, among other areas, gastric-proje...

journal_title：Neuroscience

authors： Jiang Y,Coleman FH,Kopenhaver Doheny K,Travagli RA

更新日期：2018-10-15 00:00:00

abstract：:The main neuronal population of the striatum is composed of the medium spiny neurones (MSNs). In fact several sub-populations of MSNs can be distinguished according to the striatal compartment (striosomes and matrix) to which they belong, their afferents and their sites of projection, their biochemical markers and the...

journal_title：Neuroscience

authors： Venance L,Glowinski J

更新日期：2003-01-01 00:00:00

abstract：:Clinical observations have shown a link for the high comorbid rate between smoking and psychiatric disorders, including anxiety disorders. However, little is known about the neural mechanism underlying the progression from nicotine dependence to an anxiety disorder. A deficit in fear extinction in general is considere...

journal_title：Neuroscience

authors： Tian S,Gao J,Han L,Fu J,Li C,Li Z

更新日期：2008-06-02 00:00:00

abstract：:We have recently identified a third subtype of glutamate vesicular transporter (VGLUT) named VGLUT3. In the present study, we provide a detailed account of the regional and cellular distributions of VGLUT3 in the rat brain, using specific nucleotide probes and antisera. The distribution of VGLUT3 protein was compared ...

journal_title：Neuroscience

authors： Herzog E,Gilchrist J,Gras C,Muzerelle A,Ravassard P,Giros B,Gaspar P,El Mestikawy S

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:Electrophysiological responses to auditory stimuli have provided a useful means of elucidating mechanisms and evaluating treatments in psychiatric disorders. Deficits in gating during paired-click tasks and lack of mismatch negativity following deviant stimuli have been well characterized in patients with ...

journal_title：Neuroscience

authors： Ehrlichman RS,Gandal MJ,Maxwell CR,Lazarewicz MT,Finkel LH,Contreras D,Turetsky BI,Siegel SJ

更新日期：2009-01-23 00:00:00

abstract：:Thymosin beta4 is a major actin-sequestering peptide widely distributed in mammalian tissues, including the nervous system. In the present study, we analyse the expression of thymosin beta4 in normal and kainate-treated rat forebrain. In untreated animals, thymosin beta4 messenger RNA is mainly expressed in neurons of...

journal_title：Neuroscience

authors： Carpintero P,Anadón R,Díaz-Regueira S,Gómez-Márquez J

更新日期：1999-01-01 00:00:00

abstract：:Orexins (OX), also called hypocretins, are bioactive peptides secreted from glucose-sensitive neurons in the lateral hypothalamus linking appetite, arousal and neuroendocrine-autonomic control. Here, OX-A was found to cause a slow-onset long-term potentiation of synaptic transmission (LTPOX) in the hippocampus of youn...

journal_title：Neuroscience

authors： Selbach O,Doreulee N,Bohla C,Eriksson KS,Sergeeva OA,Poelchen W,Brown RE,Haas HL

更新日期：2004-01-01 00:00:00

abstract：:Transient receptor potential vanilloid 1 (TRPV1), vanilloid 2 (TRPV2) and melastatin 8 (TRPM8) are thermosensitive cation channels expressed on primary sensory neurons. In contrast to TRPV1, which is present on nociceptive primary afferents and keratinocytes in human skin, less is known about the distribution of TRPV2...

journal_title：Neuroscience

authors： Axelsson HE,Minde JK,Sonesson A,Toolanen G,Högestätt ED,Zygmunt PM

更新日期：2009-09-15 00:00:00

abstract：:L-arginine, a semi-essential amino acid, can be metabolized to form a number of bioactive molecules. Nitric oxide (NO), generated by NO synthase (NOS) from L-arginine, has been strongly implicated in the aging process. Agmatine, decarboxylated arginine, regulates the production of NO and other metabolites of L-arginin...

journal_title：Neuroscience

authors： Rushaidhi M,Collie ND,Zhang H,Liu P

更新日期：2012-08-30 00:00:00

abstract：:Central oxytocin plays an important role in regulating emotionality. The amygdala expresses gonadal steroid-sensitive oxytocin binding sites in both the central and medial sub-nuclei, although the densities markedly differ between these nuclei. These studies examined the in vitro electrophysiological effects of oxytoc...

journal_title：Neuroscience

authors： Terenzi MG,Ingram CD

更新日期：2005-01-01 00:00:00

abstract：:Calcium entry into the postsynaptic neuron through N-methyl-D-aspartate-type glutamate receptors (NMDARs) triggers the induction of long-term potentiation (LTP), which is considered to contribute to synaptic plasticity and plays a critical role in behavioral learning. We report here that activin, a member of the trans...

journal_title：Neuroscience

authors： Kurisaki A,Inoue I,Kurisaki K,Yamakawa N,Tsuchida K,Sugino H

更新日期：2008-02-19 00:00:00

abstract：:Brainstem networks generating the respiratory rhythm in lampreys are still not fully characterized. In this study, we described the patterns of respiratory activities and we identified the general location of underlying neural networks. In a semi-intact preparation including the brain and gills, rhythmic discharges we...

journal_title：Neuroscience

authors： Martel B,Guimond JC,Gariépy JF,Gravel J,Auclair F,Kolta A,Lund JP,Dubuc R

更新日期：2007-08-10 00:00:00

abstract：:The cholinergic agonist nicotine facilitates detection of invalidly cued trials in location-cueing paradigms and reduces the associated neural activity in human inferior parietal cortex. By using functional magnetic resonance imaging we test the hypothesis that the nicotinic modulation of attentional reorienting may r...

journal_title：Neuroscience

authors： Thiel CM,Fink GR

更新日期：2008-03-18 00:00:00

abstract：:To study the effect of inositol 1,4,5-trisphosphate (IP(3)) in isolated frog vomeronasal microvillar receptor neurones, whole-cell recordings were performed with 0.5 microM caged IP(3) dissolved in the pipette solution. IP(3) was released by photolysis of caged IP(3) initiated by a 0.8-ms ultraviolet flash from a xeno...

journal_title：Neuroscience

authors： Gjerstad J,Valen EC,Trotier D,Døving K

更新日期：2003-01-01 00:00:00

abstract：:Dopamine is a neurotransmitter crucial for motor, motivational, and reward-related functions. Our aim was to determine the effect of a palatable maternal diet on the transcriptional regulation of dopaminergic-related genes during perinatal development of rat offspring. For that, female offspring from dams fed with a c...

journal_title：Neuroscience

authors： Rossetti MF,Schumacher R,Gastiazoro MP,Lazzarino GP,Andreoli MF,Stoker C,Varayoud J,Ramos JG

更新日期：2020-01-01 00:00:00

abstract：:In the glomerular layer of the rat main olfactory bulb, we previously reported three chemically defined interneuron groups: GABA-like immunoreactive, calretinin-immunoreactive and Calbindin-D28k-immunoreactive groups [Kosaka K. et al. (1995) Neurosci. Res. 23, 73-88]. In the present study, we analysed the structural f...

journal_title：Neuroscience

authors： Kosaka K,Toida K,Margolis FL,Kosaka T

更新日期：1997-02-01 00:00:00

abstract：:The expression pattern of the pannexin2 protein (Px2) in healthy and ischemized brains of adult rats was investigated. A polyclonal antibody for rat Px2 was generated in chicken and purified for affinity. This antibody was used to study by Western blot, Enzyme-Linked Immunosorbent Assay, and immunohistochemistry, the ...

journal_title：Neuroscience

authors： Zappalà A,Li Volti G,Serapide MF,Pellitteri R,Falchi M,La Delia F,Cicirata V,Cicirata F

更新日期：2007-09-07 00:00:00

abstract：:Retinitis pigmentosa (RP) is a heterogeneous group of retinal degenerative diseases in which the final pathological feature is photoreceptor cell apoptosis. Currently, the pathogenesis of RP remains poorly understood and therapeutics are ineffective. 17β-Oestradiol (βE2) is universally acknowledged as a neuroprotectiv...

journal_title：Neuroscience

authors： Xiong YC,Chen T,Yang XB,Deng CL,Ning QL,Quan R,Yu XR

更新日期：2021-01-01 00:00:00

abstract：:Cholesterol is an essential substance for maintaining normal structure and function of the brain. But unfortunately, a long-term high-cholesterol diet can lead to a variety of pathological changes of the brain such as β-amyloid (Aβ) accumulation, Tau hyperphosphorylation, reactive gliosis, neuroinflammation, neuronal ...

journal_title：Neuroscience

authors： Chen YL,Wang LM,Chen Y,Gao JY,Marshall C,Cai ZY,Hu G,Xiao M

更新日期：2016-03-01 00:00:00

abstract：:Pathological forms of the microtubule-associated protein tau are involved in a large group of neurodegenerative diseases named tauopathies, including frontotemporal lobar degeneration (FTLD-tau). K369I mutant tau transgenic mice (K3 mice) recapitulate neural and behavioural symptoms of FTLD, including tau aggregates i...

journal_title：Neuroscience

authors： Mo M,Jönsson ME,Mathews MA,Johnstone D,Ke YD,Ittner LM,Balleine BW,Furlong TM,Camp AJ

更新日期：2020-11-21 00:00:00

abstract：:GABA(A) functioning has been implicated in anxiety and depressive disorders. In this regard, we suggested that in addition to analyzing GABA(A) and the subunits that comprise the GABA(A) receptor, it might be profitable to assess the coordinated expression of subunits that comprise the GABA(A) receptor cassette. We de...

journal_title：Neuroscience

authors： Poulter MO,Du L,Zhurov V,Merali Z,Anisman H

更新日期：2010-02-17 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChRs) produce widespread and complex effects on neocortex excitability. We studied how heteromeric nAChRs regulate inhibitory post-synaptic currents (IPSCs), in fast-spiking (FS) layer V neurons of the mouse frontal area 2 (Fr2). In the presence of blockers of ionotropic glutamate ...

journal_title：Neuroscience

authors： Aracri P,Meneghini S,Coatti A,Amadeo A,Becchetti A

更新日期：2017-01-06 00:00:00

abstract：:Cocaine's multiple pharmacological substrates are ubiquitously present in the peripheral and central nervous system. Thus, upon its administration, cocaine acts in the periphery before directly acting in the brain. We determined whether cocaine alters ventral tegmental area (VTA) neuronal activity via its peripheral a...

journal_title：Neuroscience

authors： Mejías-Aponte CA,Kiyatkin EA

更新日期：2012-04-05 00:00:00