Serum progesterone concentrations on the day after human chorionic gonadotropin administration and progesterone/oocyte ratios predict in vitro fertilization/embryo transfer outcome.

Abstract:

PURPOSE:In gonadotropin-releasing hormone analogue-pretreated in vitro fertilization-embryo transfer cycles, pregnancy rates are inversely related to serum progesterone levels on the day of administration of human chorionic gonadotropin. The relationship of the progesterone concentration on other days in the periovulatory period to pregnancy rates in such cycles is little studied. We therefore retrospectively analyzed the relationship between progesterone concentrations on the day after human chorionic gonadotropin and pregnancy in 114 cycles, 28 and 23 of which produced clinical and ongoing/delivered pregnancies, respectively. To assess the effect of the extent of follicular luteinization on success, we also studied the relationship between the progesterone concentration per oocyte retrieved and pregnancy for the day of and day after human chorionic gonadotropin. RESULTS:Progesterone concentrations on the day after human chorionic gonadotropin were inversely associated with clinical pregnancy by multiple logistic regression analysis (P < 0.05). Progesterone/oocyte ratios were inversely associated with clinical pregnancy (P < 0.05) and ongoing/delivered pregnancy (P < 0.02) for both the day of and the day after human chorionic gonadotropin. CONCLUSION:The study results extend the window of time during which elevated progesterone concentration is associated with poor outcome to at least 2 days. This finding is consistent with hypothetical mechanisms attributing the link between progesterone concentration and outcome to either endometrial or follicle/oocyte events. The association of lack of follicular luteinization (low progesterone per oocyte ratios) and favorable outcome suggests a predominant effect of progesterone on follicle/oocyte quality. Further studies are needed to clarify the mechanisms underlying the association between progesterone and in vitro fertilization-embryo transfer outcome.

journal_name

J Assist Reprod Genet

authors

Burns WN,Witz CA,Klein NA,Silverberg KM,Schenken RS

doi

10.1007/BF02213692

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

17-23

issue

1

eissn

1058-0468

issn

1573-7330

journal_volume

11

pub_type

临床试验,杂志文章
  • Performance comparison of two whole genome amplification techniques in frame of multifactor preimplantation genetic testing.

    abstract:PURPOSE:To compare multiple displacement amplification and OmniPlex whole genome amplification technique performance during array comparative genome hybridization (aCGH), Sanger sequencing, SNaPshot and fragment size analysis downstream applications in frame of multifactor embryo preimplantation genetic testing. METHO...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1187-4

    authors: Volozonoka L,Perminov D,Korņejeva L,Alkšere B,Novikova N,Pīmane EJ,Blumberga A,Kempa I,Miskova A,Gailīte L,Fodina V

    更新日期:2018-08-01 00:00:00

  • Altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers.

    abstract:PURPOSE:The study aims to determine whether there is an altered bivalent positioning in metaphase I human spermatocytes from Robertsonian translocation carriers. METHODS:Metaphase I human spermatocytes from three 45,XY,der(13;14)(q10;q10) individuals and a 45,XY,der(14;15)(q10;q10) individual were analyzed. Proximity ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-016-0809-y

    authors: Solé M,Blanco J,Valero O,Vergés L,Vidal F,Sarrate Z

    更新日期:2017-01-01 00:00:00

  • Serum leptin elevation in obese women with PCOs: a continuing controversy.

    abstract:PURPOSE:To evaluate leptin levels in a sample of obese women with PCOS and compare the results with obese and non-obese control, to be ultimately correlated with BMI, and insulin sensitivity. METHODS:Leptin and insulin assays by immuno-radiometric method, glucose assay by enzymatic colorimetric method. RESULTS:Leptin...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/b:jarg.0000046204.81682.67

    authors: Saleh HA,El-Nwaem MA,El-Bordiny MM,Maqlad HM,El-Mohandes AA,Eldaqaq EM

    更新日期:2004-10-01 00:00:00

  • Reactive oxygen species-induced alterations in H19-Igf2 methylation patterns, seminal plasma metabolites, and semen quality.

    abstract:PURPOSE:This study was conducted in order to investigate the effects of reactive oxygen species (ROS) levels on the seminal plasma (SP) metabolite milieu and sperm dysfunction. METHODS:Semen specimens of 151 normozoospermic men were analyzed for ROS by chemiluminescence and classified according to seminal ROS levels [...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1350-y

    authors: Darbandi M,Darbandi S,Agarwal A,Baskaran S,Dutta S,Sengupta P,Khorram Khorshid HR,Esteves S,Gilany K,Hedayati M,Nobakht F,Akhondi MM,Lakpour N,Sadeghi MR

    更新日期:2019-02-01 00:00:00

  • Is AMH a regulator of follicular atresia?

    abstract::We discuss the hypothesis that AMH is an intraovarian regulator that inhibits follicular atresia within the human ovary. Several indirect lines of evidence derived from clinical and basic science studies in a variety of different patient populations and model systems collectively support this hypothesis. Evidence pres...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10815-014-0328-7

    authors: Seifer DB,Merhi Z

    更新日期:2014-11-01 00:00:00

  • A distribution of two SNPs in exon 10 of the FSHR gene among the women with a diminished ovarian reserve in Ukraine.

    abstract:PURPOSE:To evaluate the association between phenotype and follicle stimulating hormone receptor (FSHR) genotype in women with ovarian dysfunction and patients with "poor response" to gonadotropin stimulation of ovulation. METHODS:FSHR gene SNPs were analyzed by PCR and RFLP. "Poor responders" (ovarian dysfunction) gro...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-008-9279-1

    authors: Livshyts G,Podlesnaja S,Kravchenko S,Sudoma I,Livshits L

    更新日期:2009-01-01 00:00:00

  • Improvement of IVF outcome in poor responders by discontinuation of GnRH analogue during the gonadotropin stimulation phase--a function of improved embryo quality.

    abstract:PURPOSE:To assess the efficacy of a protocol involving the discontinuation of the GnRH analogue at the mid-phase of ovarian stimulation for IVF in patients with a previous poor response. METHODS:Prospective case-control evaluation compared with same patient's previous performance. Thirty-six patients enrolled in an IV...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 临床试验,杂志文章

    doi:10.1023/a:1009476411762

    authors: Schachter M,Friedler S,Raziel A,Strassburger D,Bern O,Ron-el R

    更新日期:2001-04-01 00:00:00

  • Application of touch FISH in the study of mosaic tetraploidy and maternal cell contamination in pregnancy losses.

    abstract:PURPOSE:karyotype is a well established technique in the study of spontaneous miscarriages but is associated with selective overgrowth of maternal cells and other culture artefact (spp) such as tetraploidy, which could mask the true karyotype of the conceptus. METHODS:328 cases of pregnancy losses were studied by kary...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-010-9460-1

    authors: Dória S,Lima V,Carvalho B,Moreira ML,Sousa M,Barros A,Carvalho F

    更新日期:2010-11-01 00:00:00

  • Low-dose aspirin does not increase implantation rates in patients undergoing intracytoplasmic sperm injection: a prospective randomized study.

    abstract:PURPOSE:The aim was to evaluate the effect of aspirin on pregnancy and implantation rates in an unselected group of patients undergoing intracytoplasmic sperm injection (ICSI). METHODS:Two hundred and seventy-nine patients were randomized to receive 80 mg of aspirin (n = 139) or no treatment (r = 136) starting from th...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1023/a:1026491426423

    authors: Urman B,Mercan R,Alatas C,Balaban B,Isiklar A,Nuhoglu A

    更新日期:2000-11-01 00:00:00

  • The impact of pronuclear orientation to select chromosomally normal embryos.

    abstract:PURPOSE:To find an effective method to select embryos from ICSI with better chromosomal status when preimplantation-genetic-diagnosis (PGD) is not applied. METHODS:Several morpholological evaluations were done in same embryos. Embryos from ICSI were classified on day 1 according to pronuclear-nucleoli arrangement. On ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-005-4874-x

    authors: Borges EJ,Rossi LM,Farah L,Guilherme P,Rocha CC,Ortiz V,Iaconelli AJ

    更新日期:2005-03-01 00:00:00

  • Neuropsychologic dysfunction in women following leuprolide acetate induction of hypoestrogenism.

    abstract:OBJECTIVE:The study investigated the neuropsychological status of women with induced hypoestrogenism. DESIGN:An ABA design was employed in which neuropsychological measures were repeated prior to, during, and after induction of hypoestrogenism with leuprolide acetate. SETTING:The study took place in a medical school ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/BF01204441

    authors: Varney NR,Syrop C,Kubu CS,Struchen M,Hahn S,Franzen K

    更新日期:1993-01-01 00:00:00

  • Recurrent complete hydatidiform mole: where we are, is there a safe gestational horizon? Opinion and mini-review.

    abstract::Benign hydatidiform mole, complete or partial, is the most common type of gestational trophoblastic disease (GTD) characterised by excessive trophoblastic proliferation and abnormal embryonic development. Although most complete hydatidiform moles (CHMs) are diploid androgenetic, a few cases of CHMs are biparental, cha...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10815-018-1202-9

    authors: Kalogiannidis I,Kalinderi K,Kalinderis M,Miliaras D,Tarlatzis B,Athanasiadis A

    更新日期:2018-06-01 00:00:00

  • Association study between FSHR Ala307Thr and Ser680Asn variants and polycystic ovary syndrome (PCOS) in Northern Chinese Han women.

    abstract:BACKGROUND:Polycystic ovary syndrome (PCOS) is a common complex genetic endocrinopathy. It has high heritability, and twin studies indicate that it is a complex polygenic disorder. Searching for major genes of PCOS is crucial to clarify its molecular pathogenesis. A previous genome-wide association study in Chinese wom...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-013-9979-z

    authors: Fu L,Zhang Z,Zhang A,Xu J,Huang X,Zheng Q,Cao Y,Wang L,Du J

    更新日期:2013-06-01 00:00:00

  • Comparison of basal and clomiphene citrate induced FSH and inhibin B, ovarian volume and antral follicle counts as ovarian reserve tests and predictors of poor ovarian response in IVF.

    abstract:PURPOSE:To compare basal and clomiphene citrate (CC) induced follicle-stimulating hormone (FSH), estradiol (E2), and inhibin B levels with ultrasound indices of ovarian reserve in infertile women and to test the prognostic value of these tests on response to ovarian stimulation in in vitro fertilization (IVF). METHODS...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/b:jarg.0000025936.73125.b4

    authors: Erdem M,Erdem A,Gursoy R,Biberoglu K

    更新日期:2004-02-01 00:00:00

  • The contribution of mitochondrial function to reproductive aging.

    abstract:PURPOSE:The number of women attempting to conceive between the ages of 36 and 44 has increased significantly in the last decade. While it is well established that women's reproductive success dramatically declines with age, the underlying physiological changes responsible for this phenomenon are not well understood. Wi...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10815-011-9588-7

    authors: Bentov Y,Yavorska T,Esfandiari N,Jurisicova A,Casper RF

    更新日期:2011-09-01 00:00:00

  • Initial maternal serum human chorionic gonadotropin levels in pregnancies achieved after assisted reproductive technology are higher after preimplantation genetic screening and after frozen embryo transfer: a retrospective cohort.

    abstract:PURPOSE:Few published articles have compared initial hCG values across all different types of ART cycles, including cycles with fresh or frozen embryo transfer. No articles have compared initial hCG values in cycles utilizing preimplantation genetic screening (PGS). The purpose of this study is to compare initial hCG v...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-017-0987-2

    authors: Hobeika E,Singh S,Malik S,Knochenhauer ES,Traub ML

    更新日期:2017-10-01 00:00:00

  • Body-mind-spirit intervention for IVF women.

    abstract:BACKGROUND:Literature supports the efficacy of psychosocial intervention for infertile women. An eastern body-mind-spirit group intervention has been developed to help infertile women in the Chinese population cope with the distress arising from IVF treatment. METHODS:The eastern body-mind-spirit group intervention ad...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-005-6418-9

    authors: Chan CH,Chan CL,Ng SM,Ng EH,Ho PC

    更新日期:2005-12-01 00:00:00

  • Correlation of somatic cell steroid secretion and quality of generated oocytes after in-vitro stimulation of mouse follicles.

    abstract:PURPOSE:To test the possibility of follicular somatic cell steroidogenesis as a marker for quality of their embraced oocytes. METHODS:Mechanically isolated mouse preantral follicles were cultured and matured in-vitro (IVC/IVM) for study. RESULTS:During IVC/IVM, oogenesis occurred concomitantly with folliculogenesis i...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-006-9041-5

    authors: Liu HC,He Z,Rosenwaks Z

    更新日期:2006-04-01 00:00:00

  • Unbalanced X;9 translocation in an infertile male with de novo duplication Xp22.31p22.33.

    abstract:PURPOSE:Male carriers of an X-autosome translocation are generally infertile, regardless of the position of the breakpoint on the X chromosome while the pathogenicity of Xp22.3 subtelomeric duplications is under debate. To shed light into this controversy, we present a rare case, of an azoospermic male with no other si...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01405-0

    authors: Roumelioti FM,Louizou E,Karras S,Neroutsou R,Velissariou V,Gagos S

    更新日期:2019-04-01 00:00:00

  • Fertility preservation in women with cancer: a national study about French oncologists awareness, experience, and feelings.

    abstract:PURPOSE:This study was designed to evaluate patient management and quality of information given by French oncologists to cancer women concerning fertility issues and possibilities of fertility preservation. METHODS:An online survey was sent to 1161 physicians in all major cancer centers throughout France between May 2...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1251-0

    authors: Sallem A,Shore J,Ray-Coquard I,Ferreux L,Bourdon M,Maignien C,Patrat C,Wolf JP,Pocate-Cheriet K

    更新日期:2018-10-01 00:00:00

  • Do young women with unexplained infertility show manifestations of decreased ovarian reserve?

    abstract:PURPOSE:To investigate whether unexplained infertility at a young age demonstrates manifestations of decreased ovarian reserve. METHODS:A total of 100 women were divided into two equally sized groups. The study group comprised women aged ≤ 37 years diagnosed with unexplained infertility, and the control group included...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01467-0

    authors: Abrahami N,Izhaki I,Younis JS

    更新日期:2019-06-01 00:00:00

  • Morula transfer achieves better clinical outcomes than post-thawed cleavage embryos after overnight culture in frozen embryo transfer (FET) cycles.

    abstract:PURPOSE:This study aimed to investigate the clinical outcomes of morula stage transfer derived from post-thawed cleavage embryos undergoing overnight culture in frozen embryo transfer (FET) cycles. METHODS:We performed a retrospective study that included 392 FET cycles with 784 thawed embryos undergoing overnight cult...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-020-01708-7

    authors: Hui D,Han X,Wang X,Ren W,Lei X,Liu J,Dong L,Li H

    更新日期:2020-04-01 00:00:00

  • Gene-environment interaction among GSTT1, PON2 polymorphisms and organic solvents on gestational age in a Chinese women cohort.

    abstract:PURPOSE:To investigate interactions on gestational age among two environmental risk factors and four maternal genetic polymorphisms: organic solvents, passive smoking, CYP1A1 rs4646903 (MspI), EPHX1 rs2234922 (His139Arg), GSTT1 and PON2 rs12026 (Ala148Gly). METHODS:A pregnant women cohort was conducted at Beijing Yans...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-014-0256-6

    authors: Li S,Fang K,Wang W,Hu Y,Chen D

    更新日期:2014-07-01 00:00:00

  • The role of anti-Müllerian hormone (AMH) in ovarian disease and infertility.

    abstract:PURPOSE:In this review, the current knowledge on anti-Müllerian hormone (AMH) is presented, concerning its value in disease and IVF treatment as well as in terms of its prospective clinical use. METHODS:AMH is becoming the most appropriate biomarker for the ovarian reserve measured predominantly for assisted reproduct...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10815-019-01622-7

    authors: Bedenk J,Vrtačnik-Bokal E,Virant-Klun I

    更新日期:2020-01-01 00:00:00

  • A comparison of oocyte donors' and gestational carriers/surrogates' attitudes towards third party reproduction.

    abstract:PURPOSE:This study was designed to compare levels of satisfaction for ovum donors and gestational carriers/surrogates (GCS), investigate attitudes, and explore beliefs about the role genetics, gestation, and environment play in various characteristics. DESIGN:An east coast IVF center and two California-based agencies ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/a:1020306402235

    authors: Bravennan AM,Corson SL

    更新日期:2002-10-01 00:00:00

  • Intrauterine insemination: is the timing correct?

    abstract:OBJECTIVE:To evaluate the impact of follicle rupture on pregnancy rate in intrauterine insemination. MATERIAL AND METHOD:Retrospective cohort study. Evidence of follicle rupture was assessed by transvaginal ultrasonography following IUI. Two hundred ninety-six couples with unexplained infertility and 121 couples with ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-008-9247-9

    authors: Kucuk T

    更新日期:2008-08-01 00:00:00

  • Fertilization of bovine oocytes induced solely with combined laser microbeam and optical tweezers.

    abstract:PURPOSE:Our purpose was to show that fertilization of oocytes can be obtained solely by laser light-mediated manipulation of gametes. METHOD:A small channel was drilled into the zona pellucida of bovine oocytes using an ultraviolet (UV)-laser microbeam. Highly diluted cattle sperm were not able to fertilize the laser ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/BF02065947

    authors: Clement-Sengewald A,Schütze K,Ashkin A,Palma GA,Kerlen G,Brem G

    更新日期:1996-03-01 00:00:00

  • Social media in the REI clinic: what do patients want?

    abstract:PURPOSE:To elicit patient preferences for social media utilization and content in the infertility clinic. METHODS:This was a cross-sectional survey study conducted in three US fertility practices. Women presenting to the infertility clinic for an initial or return visit were offered an anonymous voluntary social media...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1189-2

    authors: Broughton DE,Schelble A,Cipolla K,Cho M,Franasiak J,Omurtag KR

    更新日期:2018-07-01 00:00:00

  • Evidence of metabolic activity during low-temperature ovarian tissue preservation in different media.

    abstract:PURPOSE:Although ovarian tissue transportation has been validated for up to 24 h, there is no standard protocol to date. We aimed to elucidate how existing media currently used for ovarian tissue transportation affect ovarian tissue metabolism and cell viability. METHODS:Cow ovarian fragments were immersed in 0.9% NaC...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-020-01935-y

    authors: Vilela JMV,Dolmans MM,Maruhashi E,Blackman MCNM,Sonveaux P,Miranda-Vilela AL,Amorim CA

    更新日期:2020-10-01 00:00:00

  • The effect of elevated serum progesterone during ovulation induction in in vitro fertilization-embryo transfer.

    abstract:OBJECTIVE:Our purpose was to determine whether elevated progesterone (P) during ovulation induction in IVF-ET cycles is a poor prognostic factor for achieving pregnancy. DESIGN:We retrospectively reviewed 672 consecutive IVF-ET cycles in which ovulation was performed using luteal LA downregulation and hMG. SETTING:Th...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/BF02069639

    authors: Huang JC,Jackson KV,Hornstein MD,Ginsburg ES

    更新日期:1996-09-01 00:00:00