The prevalence study on restriction fragment length polymorphism analysis for the detection of hemophilia A carrier.

Abstract:

:We have analyzed two (BclI and XbaI) intragenic restriction fragment length polymorphisms (RFLPs) and St14 (DXS52) variable number of tandem repeats (VNTR) by rapid PCR method in 97 unrelated normal subjects. The incidences for positive Bc1I and XbaI polymorphic sites in the Koreans were 81% and 72%, respectively, which were higher than other ethnic groups but similar to that reported in the Chinese or Japanese, giving the heterozygosity rate of 0.32 and 0.40, respectively. The amplified allele size was 880 bp with no other polymorphism in the analysis of St14 (DXS52) VNTR. This finding should be taken into account in the planning of a prenatal diagnosis program for ethnic Koreans.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Song KS,Lee CH,Chung CS,Lee K,Yang YH,Kim KY

doi

10.3349/ymj.1993.34.3.239

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

239-42

issue

3

eissn

0513-5796

issn

1976-2437

journal_volume

34

pub_type

杂志文章
  • Identification of differentially expressed genes in papillary thyroid cancers.

    abstract:PURPOSE:Techniques designed to identify differentially expressed genes (DEGs) in tumors have become important in modern pathology. Genefishing technique using the annealing control primer (ACP) system has recently been developed to screen for DEG transcripts. We tried to identify DEGs involved in papillary thyroid canc...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2009.50.1.60

    authors: Lee KY,Huang SM,Li S,Kim JM

    更新日期:2009-02-28 00:00:00

  • Diagnosis of overt disseminated intravascular coagulation: a comparative study using criteria from the International Society versus the Korean Society on Thrombosis and Hemostasis.

    abstract:PURPOSE:Since 1993, Koreans have used diagnostic criteria set by the Korean Society on Thrombosis and Hemostasis (KSTH) in the diagnosis of overt disseminated intravascular coagulation (DIC). In 2001, the Scientific and Standardization Committee (SCC) of the International Society on Thrombosis and Hemostasis (ISTH) pro...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2007.48.4.595

    authors: Lee JH,Song JW,Song KS

    更新日期:2007-08-31 00:00:00

  • Ischemic stroke among the patients with end-stage renal disease who were undergoing maintenance dialysis.

    abstract:PURPOSE:In spite of higher incidence of stroke in end-stage renal disease (ESRD) patients compared to general population, the risk factor for stroke which is specific to ESRD is not fully understood. The ESRD patients who develop stroke may have certain additional risk factors compared to ESRD patients without stroke. ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2012.53.5.894

    authors: Jung S,Kwon SB,Hwang SH,Noh JW,Lee YK

    更新日期:2012-09-01 00:00:00

  • Sagittal plane analysis of adolescent idiopathic scoliosis after VATS (video-assisted thoracoscopic surgery) anterior instrumentations.

    abstract::Radiographic sagittal plane analysis of VATS (video-assisted thoracoscopic surgery) anterior instrumentation for adolescent idiopathic scoliosis. This is retrospective study. To report, in details about effects of VATS anterior instrumentation on the sagittal plane. Evaluations of the surgical outcome of scoliosis hav...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2007.48.1.90

    authors: Kim HS,Lee CS,Jeon BH,Park JO

    更新日期:2007-02-28 00:00:00

  • Granular Cell Tumors on Unusual Anatomic Locations.

    abstract::Granular cell tumors (GCTs) are soft tissue tumors, which are thought to be derived from Schwann cells. Although most GCTs are reported to arise in tongue and oral cavity (30-50%), they can appear on any anatomic sites, even visceral organs. Herein, we report 5 cases of GCTs on unusual anatomic locations, such as palm...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2015.56.6.1731

    authors: Kim HJ,Lee MG

    更新日期:2015-11-01 00:00:00

  • Evaluation of CSF motion in syringomyelia with spatial modulation of magnetization (SPAMM).

    abstract::CSF flow dynamics has been known to have a key role the pathogenesis of syringomyelia. Our purpose was to evaluate the CSF flow pattern in syringomyelia with spatial modulation of magnetization (SPAMM) that can depict directional flow, and to determine the relationship between flow dynamics and clinical outcome after ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2002.43.1.37

    authors: Lee SK,Chung TS,Kim YS

    更新日期:2002-02-01 00:00:00

  • Relation among the gross motor function, manual performance and upper limb functional measures in children with spastic cerebral palsy.

    abstract:PURPOSE:The objective of this study was to describe hand function in relation with gross motor function and subtype of spastic cerebral palsy and to investigate the relationships among gross motor function, bimanual performance, unimanual capacity and upper limb functional measures in children with spastic cerebral pal...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2013.54.2.516

    authors: Park ES,Rha DW,Park JH,Park DH,Sim EG

    更新日期:2013-03-01 00:00:00

  • Early repolarization and myocardial scar predict poorest prognosis in patients with coronary artery disease.

    abstract:PURPOSE:Recent studies show positive association of early repolarization (ER) with the risk of life-threatening arrhythmias in patients with coronary artery disease (CAD). This study was to investigate the relationships of ER with myocardial scarring and prognosis in patients with CAD. MATERIALS AND METHODS:Of 570 con...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2014.55.4.928

    authors: Lee HY,Mun HS,Wi J,Uhm JS,Shim J,Kim JY,Pak HN,Lee MH,Joung B

    更新日期:2014-07-01 00:00:00

  • Interaction between warfarin and the herbal product Shengmai-yin: a case report of intracerebral hematoma.

    abstract::A 71-year-old man was stable on warfarin (2.25 mg daily) therapy with an international normalized ratio (INR) of 1.8-2.2 after a heart valve replacement surgery. Recently, he consumed the liquid-like herbal product called shengmai-yin (10 mL daily) against medical advice. Seven days after the daily consumption of shen...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.5.793

    authors: Su Q,Li Y

    更新日期:2010-09-01 00:00:00

  • Korean nationwide surveillance of antimicrobial resistance in 2000 with special reference to vancomycin resistance in enterococci, and expanded-spectrum cephalosporin and imipenem resistance in gram-negative bacilli.

    abstract::Antimicrobial resistance surveillance is necessary to determine the size of the problem and to guide empirical selection of antimicrobial agents for treating infected patients. The aim of this study was to analyze the results of susceptibility tests performed by hospitals participating in the Korean Nationwide Surveil...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.4.571

    authors: Lee KW,Kim MY,Kang SH,Kang JO,Kim EC,Choi TY,Chong YS,Korean Nationwide Surveillance Of Antimicrobial Resistance Group.

    更新日期:2003-08-30 00:00:00

  • Protocol-Based Resuscitation for Septic Shock: A Meta-Analysis of Randomized Trials and Observational Studies.

    abstract:PURPOSE:Owing to the recommendations of the Surviving Sepsis Campaign guidelines, protocol-based resuscitation or goal-directed therapy (GDT) is broadly advocated for the treatment of septic shock. However, the most recently published trials showed no survival benefit from protocol-based resuscitation in septic shock p...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,meta分析

    doi:10.3349/ymj.2016.57.5.1260

    authors: Lee WK,Kim HY,Lee J,Koh SO,Kim JM,Na S

    更新日期:2016-09-01 00:00:00

  • Bilateral coronary arteriovenous fistula coexistent with atrial septal defect and pulmonary stenosis.

    abstract::A coronary arteriovenous fistula consists of a communication between a coronary artery and a cardiac chamber, a great artery or the vena cava. It is the most common anomaly that can affect coronary perfusion. Bilateral involvement of coronary fistula, however, constitutes an uncommon subgroup of coronary arteriovenous...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1997.38.3.190

    authors: Ha JW,Lee HJ,Lee JY,Kim HY,Yoon J,Choe KH

    更新日期:1997-06-01 00:00:00

  • Effect of Dialysis on Aryl Hydrocarbon Receptor Transactivating Activity in Patients with Chronic Kidney Disease.

    abstract:PURPOSE:Elevated aryl hydrocarbon receptor (AhR) transactivating (AHRT) activity and uremia in chronic kidney disease (CKD) may interact with each other, further complicating the disease course. In this study, we prospectively estimated serum AHRT activity using a highly sensitive cell-based AhR-dependent luciferase ac...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2020.61.1.56

    authors: Kim JT,Kim SH,Min HK,Jeon SJ,Sung SA,Park WH,Lee HK,Choi HS,Pak YK,Lee SY

    更新日期:2020-01-01 00:00:00

  • Initial experiences with proton MR spectroscopy in treatment monitoring of mitochondrial encephalopathy.

    abstract:PURPOSE:Mitochondrial encephalopathy (ME) is a rare disorder of energy metabolism. The disease course can roughly be evaluated by clinical findings. The purpose of this study was to evaluate metabolic spectral changes using proton MR spectroscopy (MRS), and to establish a way to monitor ME by neuroimaging. MATERIALS A...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.5.672

    authors: Lee SK,Kim J,Kim HD,Lee JS,Lee YM

    更新日期:2010-09-01 00:00:00

  • Absence of frontal sinus in Turkish individuals.

    abstract::The frontal sinus has been used for personal identification since the early part of the 20th century as a result of its tremendous interindividual variation. The frontal sinus is present in approximately 90% of adults. However, some populations have a higher proportion of people without a frontal sinus. This study inv...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2003.44.2.215

    authors: Aydinlioğlu A,Kavakli A,Erdem S

    更新日期:2003-04-30 00:00:00

  • Strategies to improve dendritic cell-based immunotherapy against cancer.

    abstract::Dendritic cells (DCs) play a pivotal role in T cell-mediated immunity and have been shown to induce strong antitumor immune responses in vitro and in vivo. Various approaches utilizing different vaccine cell formats, cell numbers, vaccination schedule, site of vaccination and maturation stages of DCs were investigated...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2004.45.Suppl.48

    authors: Song SY,Kim HS

    更新日期:2004-06-30 00:00:00

  • Leptin as a modulator of neuroendocrine function in humans.

    abstract::Leptin, a peptide hormone secreted by adipocytes in proportion of the amount of energy stored in fat, plays a central role in regulating human energy homeostasis. In addition, leptin plays a significant permissive role in the physiological regulation of several neuroendocrine axes, including the hypothalamic-pituitary...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2012.53.4.671

    authors: Khan SM,Hamnvik OP,Brinkoetter M,Mantzoros CS

    更新日期:2012-07-01 00:00:00

  • Elevated serum C-reactive protein as a prognostic marker in small cell lung cancer.

    abstract:PURPOSE:Elevated C-reactive protein (CRP) is associated with poor prognosis in several tumor types. The purpose of this study was to investigate serum CRP as a prognostic marker in small cell lung cancer (SCLC). MATERIALS AND METHODS:The pretreatment serum CRP level was measured in 157 newly diagnosed SCLC patients, a...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2012.53.1.111

    authors: Hong S,Kang YA,Cho BC,Kim DJ

    更新日期:2012-01-01 00:00:00

  • A case of extensive spinal cysticercosis involving the whole spinal canal in a patient with a history of cerebral cysticercosis.

    abstract::Although cysticercosis is the most common parasitic disease affecting the central nervous system, spinal cysticercosis is rare. A rare form of spinal cysticercosis involving the whole spinal canal is presented. A 45-year-old Korean male had a history of intracranial cysticercosis and showed progressive paraparesis. Sp...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2009.50.4.582

    authors: Shin DA,Shin HC

    更新日期:2009-08-31 00:00:00

  • Utilization characteristics of health care service for rheumatoid arthritis patients in Korea.

    abstract::The purpose of this study was to determine the factors which were responsible for delaying early diagnosis and optimal management of rheumatoid arthritis (RA) in Korea. We interviewed 109 outpatients diagnosed as RA being treated by rheumatologists, and we eventually analyzed 98 patients' data. The median length of ti...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1998.39.3.247

    authors: Cho KJ,Jang SH,Lee SK,Doh WS

    更新日期:1998-06-01 00:00:00

  • Long term effects of IUD on the human endometrium. Histologic, histochemical and ultrastructural studies.

    abstract::To evaluate the longterm effects of a IUD on the human endometrium and find the possible contraceptive mechanism of the IUD, histologic, histochemical, and ultrastructural studies of human endometrial biopsies from 44 normal contorls and 178 IUD wearers were made. Histologic findings included interstitial hemorrhage,...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1983.24.2.141

    authors: Lee YB,Kim CS,Ro JY,Kwak HM,Song CH

    更新日期:1983-01-01 00:00:00

  • A case of urethral replacement with polytetrafluoro-ethylene graft for multiple anterior urethral strictures.

    abstract::Recently, the authors had an opportunity to treat a 73-year-old male patient who was transferred to our institution with problematic multiple strictures of the anterior urethra subsequent to a suprapubic cystostomy. A proximal urethra was reconstructed with scrotal skin, but due to the shortage of distal skin, as a la...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.1989.30.2.198

    authors: Choi HK,Chang SK

    更新日期:1989-01-01 00:00:00

  • Clinicopathologic characteristics associated with complications and long-term outcomes of endoscopic papillectomy for adenoma.

    abstract:PURPOSE:Endoscopic papillectomy (EP) is currently employed for the treatment of ampullary adenoma. This study aimed to evaluate the clinical, endoscopic, and histologic characteristics related to complications and long-term outcomes of EP. MATERIALS AND METHODS:Thirty-nine patients underwent EP for ampullary adenoma. ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2014.55.3.644

    authors: Shim CN,Chung MJ,Bang S,Park SW,Song SY,Chung JB,Park JY

    更新日期:2014-05-01 00:00:00

  • Association of plasma retinol-binding protein 4, adiponectin, and high molecular weight adiponectin with insulin resistance in non-diabetic hypertensive patients.

    abstract:PURPOSE:The aim of this study was to determine whether retinol-binding protein 4 (RBP4), adiponectin and high molecular weight (HMW) adiponectin are associated with insulin resistance (IR) and metabolic parameters in non-diabetic hypertensive patients. Also, we sought to compare the predictive values of these adipocyto...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2010.51.3.375

    authors: Shim CY,Park S,Kim JS,Shin DJ,Ko YG,Kang SM,Choi D,Ha JW,Jang Y,Chung N

    更新日期:2010-05-01 00:00:00

  • Comparison of perioperative complications between reconstructive pelvic surgery and general gynecologic surgery.

    abstract::The purpose of this study was to compare the perioperative complication rates of reconstructive pelvic surgery and general gynecologic surgery, and to identify the predictive risk factors for perioperative complications in reconstructive pelvic surgery. The medical records of 148 reconstructive pelvic surgery patients...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2004.45.2.281

    authors: Bai SW,An JM,Shin JS,Park JH,Kim SK,Park KH

    更新日期:2004-04-30 00:00:00

  • Tissue engineering in the twenty-first century.

    abstract::In the 20th century, free tissue transfers have been successfully introduced using microvascular anastomosis techniques. Transplants not only include whole organs such as the kidney, liver and lung, but also bone, muscle and skin. However, there are a limited number of organs available for transplantation. This leads ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章,评审

    doi:10.3349/ymj.2000.41.6.685

    authors: Terada S,Sato M,Sevy A,Vacanti JP

    更新日期:2000-12-01 00:00:00

  • The expression of folate sensitive fragile sites in patients with bipolar disorder.

    abstract:PURPOSE:Genetic factors are known to be important in the etiology of bipolar disorder (BD). The fragile sites (FSs) are a very interesting subject for the study of clinical disorders. The aim of this study was to evaluate fragile sites seen in patients with bipolar disorder and find a correlation between some fragile s...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2009.50.1.137

    authors: Demirhan O,Tastemir D,Sertdemir Y

    更新日期:2009-02-28 00:00:00

  • Long Non-Coding RNA TUG1 Promotes Proliferation and Inhibits Apoptosis of Osteosarcoma Cells by Sponging miR-132-3p and Upregulating SOX4 Expression.

    abstract:PURPOSE:Long non-coding RNA taurine upregulated gene 1 (TUG1) is reported to be a vital regulator of the progression of various cancers. This study aimed to explore the exact roles and molecular mechanisms of TUG1 in osteosarcoma (OS) development. MATERIALS AND METHODS:Real-time quantitative PCR was applied to detect ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2018.59.2.226

    authors: Li G,Liu K,Du X

    更新日期:2018-03-01 00:00:00

  • Meningitis due to bacillus anthracis.

    abstract::The first case of haemorrhagic meningitis due to Bacillus anthracis in the European part of Turkey is reported here. B. anthracis, sensitive to penicillin, was isolated from the cerebrospinal fluid and blood cultures. Although appropriate therapy was administered, the patient died two days after hospitalization. ...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2005.46.1.159

    authors: Gürcan S,Akata F,Kuloğlu F,Erdoğan S,Tuğrul M

    更新日期:2005-02-28 00:00:00

  • Clinical Usefulness of Fungal Culture of EBUS-TBNA Needle Rinse Fluid and Core Tissue.

    abstract:PURPOSE:The diagnosis of pulmonary fungal infections is challenging due to the difficulty of obtaining sufficient specimens. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) needle rinse fluid has become an emerging diagnostic material. This study evaluated the role of routine fungal culture...

    journal_title:Yonsei medical journal

    pub_type: 杂志文章

    doi:10.3349/ymj.2020.61.8.670

    authors: Ko RE,Jeong BH,Huh HJ,Lee NY,Yoo H,Jhun BW,Han J,Lee K,Kim H,Kwon OJ,Um SW

    更新日期:2020-08-01 00:00:00