[Effectiveness of quarterly assessment of CEA, TPA and GICA serum levels in gastric and colorectal carcinomas: Prospective study of 174 patients undergoing radical surgery].

Abstract:

:One-hundred seventy four consecutive patients who underwent curative resection for gastric and colorectal cancer between 1983 and 1985, were studied prospectively to evaluate the roles of sequential CEA, TPA and GICA determinations and independent clinical examinations, in the early diagnosis of resectable recurrences. Sixty-six recurrences (33 from gastric and 33 from colorectal cancer) were detected between 6 and 42 months after primary surgery. In gastric cancer CEA, TPA and GICA showed a sensitivity of 64%, 73%, and 60%, and a specificity of 67%, 65% and 54% respectively. Nine patients (27%) underwent surgical treatment for the recurrent disease, and 4 of them (44.4%) had resectable recurrence, for a total resectability rate of 12%. Out of these four patients, three patients are still living after 12, 36 and 44 months respectively from re-operation without evidence of neoplastic disease. In one of these patients re-operation was performed on the basis of the elevation of the three markers, without any other clinical sign of disease, this patient had a resectable solitary hepatic recurrence. In colorectal cancer CEA, TPA and GICA showed a sensitivity of 73%, 73%, and 49%, and a specificity of 77%, 87%, and 97% respectively. Fourteen patients (42.4%) underwent surgical treatment for the recurrent disease, and 8 of them (57%) showed a resectable recurrence, for a total resectability rate of 24.2%. Six patients are still living after 9, 16, 21, 31, 41 and 53 months respectively from reoperation without evidence of neoplastic disease.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Minerva Chir

journal_title

Minerva chirurgica

authors

Barillari P,Ricci M,Broglia S,Manetti G,Cerasi A,Cesareo S,Calcaterra D,Cioè I,Caronna R,Sammartino P

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

953-61

issue

10

eissn

0026-4733

issn

1827-1626

journal_volume

49

pub_type

杂志文章
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  • [Experience in the prophylactic use of ceftriaxone in pediatric surgery].

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    authors: Inserra A,Zaccara A,Mosiello G,Serventi P,Boglino C

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  • [Duodenopancreatectomy with conservation of the pylorus].

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    authors: Lombardi M,Troiani R,Isoppi E,D'Alessandro F,Torri T,Toniolo GL,Valentini D,Vigani A,Ambrogi M,Sicari A

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  • [Acute abdomen in the elderly].

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    doi:

    authors: Pannella A,Fossa M,Palermo G,Laboranti F,De Leonardis A

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    doi:

    authors: Trummer G,Brehm K,Siepe M,Heilmann C,Schlensak C,Beyersdorf F

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  • [Approach methods to the central venous system].

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    doi:

    authors: Viti M,Invernizzi C,Bonsanti A,Tanteri M,Roffi M

    更新日期:1990-03-31 00:00:00

  • [The SITAR Project. A new approach to diagnosis and surgical indication in arteriopathic patients].

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    pub_type: 杂志文章

    doi:

    authors: Biasi G,Viola G,Vaccari E

    更新日期:1977-04-15 00:00:00

  • [Sigmoid volvulus].

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    pub_type: 杂志文章,评审

    doi:

    authors: Cabano F,Vezzulli I,Venegoni A,Resta E,De Medici A

    更新日期:1993-05-31 00:00:00

  • [Postoperative complications in the Billroth I gastrectomy].

    abstract::A series of 234 patients who underwent Billroth I gastric resection for gastric and duodenal ulcerous lesions is reported. Special attention is paid to the immediate postoperative complications whose incidence was 5.5%. Particularly serious is the dehiscence of gastroduodenal anastomosis which requires emergency recon...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Petrassi A,Petrolo F,Gradia B

    更新日期:1979-02-15 00:00:00

  • The predictive value of the clinical features of malignancy in cases of preoperative follicular thyroid neoplasia.

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    doi:

    authors: Soyder A,Unübol M,Sen O,Ozbaş S,Koçak S

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    pub_type: 杂志文章

    doi:

    authors: Bajardi G,Ricevuto G,Mastrandrea G,Latteri M,Pischedda G,Rubino G,Valenti D,Florena M

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  • [Biliodigestive fistulae. Apropos 2 cases with opposite symptomatology].

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    pub_type: 杂志文章,评审

    doi:

    authors: Picucci L,Alibrandi M,Persico Stella L,Bevilacqua M,De Nuntis S,Quondamcarlo C,Valle D

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  • [A case of pseudocyst of the right adrenal gland. Clinical case report].

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    authors: Ferraro M,Molea G

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  • [Family anamnesis, cholecystectomy and gastric resection in patients with colorectal carcinoma: a case-control study].

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    authors: Civitelli S,Civitelli B,Landini T,Pacchiarotti MC,Mancini A,Tanzini G

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  • [Iterative pulmonary metastasis. Considerations on 28 surgically treated cases].

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  • [The nutrition of the elderly surgical patient].

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    journal_title:Minerva chirurgica

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    doi:

    authors: Faccini M,Caputo P,Lavezzoli A,Manelli A,Bonandrini L

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  • [An experimental study of a new ultrasonic scalpel. Observations on the quality of the ultrasonic effect and the prospects for its clinical use on different parenchyma and tissues].

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    doi:

    authors: Palmieri B,Criscuolo M,Gozzi G

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  • [Various types of small intestine occlusion. Case contribution].

    abstract::The Authors examine retrospectively all the cases of obstruction of the small bowel operated at the surgical department of the Verbania Hospital in the last twenty years. The records of 341 cases, 1.4% of the total amount of the surgical operations carried out in the same space of time, were retrospectively reviewed. ...

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    doi:

    authors: Finocchiaro GB,Perovani-Vicari P,Togna A,Mazza S,Galimberti GB

    更新日期:1992-12-01 00:00:00

  • [Carcinoma of the male breast. Our experience].

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    authors: Cianchetti E,Cotellese R,Dell'Osa A,Nardi M,D'Aulerio A,Puglielli L,Di Sebastiano P,Saragani C,Napolitano AM

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  • [Atypical metastases from gastric carcinoma. A primary and isolated case localized in the abdominal wall].

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    doi:

    authors: Del Cimmuto P,Del Papa U,Faccia M,Astolfi A,Capanna A,Cellini G

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  • [Conservative surgery for ductal carcinoma in situ of the breast].

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    doi:

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    doi:

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  • [Surgical correction of the pectus excavatum and carinatum in the adult. Report of an unusual case of combination of the straight back and pectus excavatum].

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    doi:

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  • [Benign obstruction of the common bile duct: what is the current role of transduodenal sphincteroplasty?].

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    doi:

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  • [Follow-up of patients with Roux-technique gastric resection. Comparison of Billroth I and Billroth II gastric resections].

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    doi:

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