Abstract:
:Tests with 140 strains representing Escherichia coli, Klebsiella aerogenes, K. ozaenae, Proteus mirabilis, P. vulgaris, P. rettgeri and P. morganii in a defined medium supplemented with 0-09M dimethylamine (DMA) and 0-1M potassium nitrate showed that at least 89% of the 136 strains able to reduce nitrates produced up to 9mM dimethylnitrosamine (DMN) in 70h at 37 degrees C. Four nitratase-negative strains produced DMN from DMA in the presence of sodium nitrate. Prolonged incubation was the most important factor in determining DMN production. Stasis and persistent infection in the urinary tract, by simulating prolonged incubation of a culture, may be of importance in determining whether the potential carcinogen, DMN, could be produced in vivo by bacterial action on DMA and nitrate in urine.
journal_name
J Med Microbioljournal_title
Journal of medical microbiologyauthors
Coloe PJ,Hayward NJdoi
10.1099/00222615-9-2-211subject
Has Abstractpub_date
1976-05-01 00:00:00pages
211-23issue
2eissn
0022-2615issn
1473-5644journal_volume
9pub_type
杂志文章abstract::As Mycobacterium leprae proliferate inside macrophages, it has been speculated that catalase encoded by katG may protect the bacilli from deleterious effects of peroxide generated from the macrophage and may also play a crucial role in the survival of M. leprae in vivo. However, unlike that of M. tuberculosis, the kat...
journal_title:Journal of medical microbiology
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更新日期:2014-02-01 00:00:00
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abstract:PURPOSE:Comparative genomic analysis of strains may help us to better understand the wide diversity of their genetic profiles. The aim of this study was to analyse the genomic features of the resistome and virulome of Brazilian first methicillin-resistant Staphylococcus aureus (MRSA) isolates and their relationship to ...
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更新日期:2019-05-01 00:00:00
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更新日期:1994-03-01 00:00:00
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doi:10.1099/jmm.0.004333-0
更新日期:2009-01-01 00:00:00
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journal_title:Journal of medical microbiology
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journal_title:Journal of medical microbiology
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更新日期:2009-11-01 00:00:00
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doi:10.1099/jmm.0.001560-0
更新日期:2009-02-01 00:00:00
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journal_title:Journal of medical microbiology
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doi:10.1099/jmm.0.47282-0
更新日期:2007-11-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/00222615-46-12-987
更新日期:1997-12-01 00:00:00
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更新日期:1996-09-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/0022-1317-51-12-1107
更新日期:2002-12-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/00222615-18-2-181
更新日期:1984-10-01 00:00:00
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journal_title:Journal of medical microbiology
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doi:10.1099/jmm.0.001271
更新日期:2021-01-01 00:00:00
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journal_title:Journal of medical microbiology
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更新日期:2005-09-01 00:00:00
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更新日期:1985-12-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
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更新日期:2019-02-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/00222615-37-1-77
更新日期:1992-07-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/jmm.0.45530-0
更新日期:2004-06-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/00222615-11-4-371
更新日期:1978-11-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/jmm.0.000537
更新日期:2017-08-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/0022-1317-50-7-602
更新日期:2001-07-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/jmm.0.000748
更新日期:2018-06-01 00:00:00
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journal_title:Journal of medical microbiology
pub_type: 杂志文章
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更新日期:2017-03-01 00:00:00
abstract::A novel drug delivery system for osteomyelitis was developed in which a porous hydroxyapatite block (HAB) is loaded with antibiotic by a centrifugation method. In this study, implantation of HABs loaded with the aminoglycoside antibiotic, arbekacin, were tested in established Staphylococcus aureus osteomyelitis in the...
journal_title:Journal of medical microbiology
pub_type: 杂志文章
doi:10.1099/00222615-46-9-779
更新日期:1997-09-01 00:00:00