Abstract：
OBJECTIVE:To compare the FSH threshold level for follicle growth up to the preovulatory stage between superovulated and natural cycles. DESIGN:Normally cycling women were investigated during an untreated spontaneous cycle (control) and three cycles treated with FSH. SETTING:Infertility clinic in a university hospital. PATIENTS:Thirteen normally ovulating women with unexplained infertility. INTERVENTIONS:Follicle-stimulating hormone was injected at the single dose of six ampules on cycle day 2 without extra FSH (FSH + 0 cycle) or with extra FSH from cycle day 4 onward at the daily dose of either one ampule (FSH + 1 cycle) or two ampules (FSH + 2 cycle). MAIN OUTCOME MEASURES:Serum FSH and E2 during the follicular phase. Number of follicles and growth rate by ultrasound. RESULTS:Multiple follicular development occurred in all FSH treated cycles. In these cycles the growth rate of the first (dominant) follicle was similar to that in the control cycles. In the presence of physiological concentrations of FSH (control and FSH + 0 cycles), only one follicle was > 15 mm at midcycle. When serum FSH values increased (FSH + 1 and FSH + 2 cycles), the growth rate of the second and third in order follicles and subsequently the number of the preovulatory follicles (> 15 mm) increased in proportion to the FSH increment. CONCLUSIONS:Follicles recruited by exogenous FSH in the early follicular phase of the cycle require supraphysiological concentrations of FSH throughout the follicular phase to become preovulatory. The extra FSH acts through an increase in the growth rate of these follicles.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Lolis DE,Tsolas O,Messinis IEdoi
10.1016/s0015-0282(16)57610-9subject
Has Abstractpub_date
1995-06-01 00:00:00pages
1272-7issue
6eissn
0015-0282issn
1556-5653pii
S0015-0282(16)57610-9journal_volume
63pub_type
杂志文章abstract：:It is important to have an accurate model for calculating limits to sperm donation so as to avoid inadvertent half-sibling mating and help protect the rights and welfare of the donor- inseminated child. The most highly developed model to date cannot be used as there is inadequate regulation of donor insemination among...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.01.099
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To investigate whether antitrophoblast antibodies are associated with unexplained recurrent miscarriages, we used choriocarcinoma cells JEG-3, since these cells are negative for class I and II antigens, but they do express HLA-G, resembling an antigen expression of endovascular and interstitial trophoblasts. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.11.014
更新日期：2012-02-01 00:00:00
abstract：:Inflammatory exudates around intrauterine devices were found to produce large concentrations of prostaglandin F2alpha. To evaluate the effect of this substance, 100 semen specimens were incubated in concentrations 100 times greater than that found in normal semen. Motility indices were calculated, and significant inhi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Both partners of 198 consecutive infertile couples were evaluated. Studies in the female included clinical evaluation of ovulation for a minimum of two menstrual cycles, investigation of tubal patency, and evaluation of sperm survival in cervical mucus. Six semen specimens were analyzed from each male. Laparoscopy, sc...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42976-6
更新日期：1977-12-01 00:00:00
abstract：OBJECTIVE:To identify whether the cause, site of ductal obstruction, and characteristics of fluid aspirates are associated with the cryosurvival and fertility after thawing of sperm obtained during reconstruction of the excurrent ducts with microsurgical epididymal sperm aspiration, vasal sperm aspiration, or both. DE...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00274-4
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the diagnostic value of the crushed glass appearance of particles observed on roentgenogram after hysterosalpingography in patients with pelvic abnormalities. DESIGN:Retrospective study of 32 patients whose roentgenogram had particles with a crushed glass appearance and 16 patients without crushe...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00415-9
更新日期：1997-12-01 00:00:00
abstract：:Menopausal hormone therapy (HT) has complex biologic effects but continues to have an important clinical role in the management of vasomotor and other menopausal symptoms. The rational use of menopausal HT requires balancing the potential benefits and risks of treatment. Findings from the Women's Health Initiative (WH...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2014.02.043
更新日期：2014-04-01 00:00:00
abstract：:Serum anti-Müllerian hormone concentrations vary significantly over time and this should be taken into account when tailoring treatment protocols for patients undergoing controlled ovarian hyperstimulation (COH). Compared with FSH, serum anti-Müllerian hormone may have greater discriminatory power because of its modes...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.10.001
更新日期：2011-03-01 00:00:00
abstract：:Midluteal phase corpora lutea (CL) obtained from women induced with 50 mg (n = 5), 100 mg (n = 5), and 150 mg (n = 5) of clomiphene citrate (CC) were measured for luteinizing hormone/human chorionic gonadotropin (LH/hCG) concentrations and cytosol progesterone (P) and 17 alpha-hydroxyprogesterone (17-OHP) and compared...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the independent effects of the degree of blastocoele expansion and re-expansion and the inner cell mass (ICM) and trophectoderm (TE) grades on predicting live birth after fresh and vitrified/warmed single blastocyst transfer. DESIGN:Retrospective study. SETTING:Reproductive medical center. PATI...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.12.014
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:To determine the sensitivity and clinical significance of fluorescein isothiocyanate wheat germ agglutinin (FITC-WGA) staining of human spermatozoa. DESIGN:Percentage FITC-WGA staining was assessed in the different morphological zones of human spermatozoa and compared with fertilization rates of metaphase II...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)57499-8
更新日期：1995-04-01 00:00:00
abstract：:This study was initiated to determine whether factors are present in human sperm-free seminal plasma (HSP) that regulate the uptake and release of carnitine from sperm. Bovine caput epididymal sperm cells accumulated more carnitine than caudal sperm cells. A significant reduction in carnitine uptake by caput sperm was...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1988-05-01 00:00:00
abstract：OBJECTIVE:To determine the effects of low-dose aspirin on ovarian response, uterine and ovarian blood flow velocity, and implantation and pregnancy rates in patients undergoing IVF. DESIGN:Prospective, randomized, double-blind placebo-controlled assay. SETTING:Department of Reproductive Medicine, CER Medical Institut...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(99)00088-6
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To determine the meiotic segregation of a pericentric inversion of chromosome 8 in three carriers. DESIGN:Analysis of sperm nuclei by fluorescence in situ hybridization (FISH). SETTING:University hospital. PATIENT(S):Three males with an inv(8). INTERVENTION(S):Triple FISH with the 8q and 8p subtelomeres a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.04.056
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVE:To examine the implantation potential of embryos from assisted reproductive technology cycles with low embryo production and to assess the effects of clinical variables and embryo scores (ES) on pregnancy outcome. DESIGN:Prospective clinical study. SETTING:Assisted reproductive technology unit in a tertiary...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.05.011
更新日期：2003-12-01 00:00:00
abstract：:Gene products estrogen receptor alpha, progesterone receptor-A, retinoid X receptor alpha, insulin-like growth factor-II, insulin-like growth factor I receptor beta, platelet-derived growth factor, epithelial growth factor receptor, and BCL-2 were examined by immunohistochemistry with the aid of a tissue microarray fr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.11.104
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:To measure activin A concentrations in uterine washing fluid collected from women with couple infertility undergoing intrauterine insemination (IUI). DESIGN:Retrospective case-control study. SETTING:Tertiary university center for women's care. PATIENT(S):Fifty women, of whom 25 became pregnant after up to ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.12.125
更新日期：2010-05-01 00:00:00
abstract：:Although the general trend for delaying childbearing is generally viewed as causing infertility, its consequences on the interpregnancy interval have been unknown. A study of birth records for Swiss married women from 1969 to 2006 revealed that the woman's age at first birth has increased from 25.0 to 30.1 years, wher...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.05.078
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To examine the effects of coping and of infertility-specific and nonspecific stress on pregnancy outcomes after IVF treatment. DESIGN:Cross-sectional design controlling for potential confounding variables. Psychosocial measures were assessed on the day of embryo transfer. SETTING:Fertility clinic in Greece....
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.02.096
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVE:To study the morphological changes of apoptotic oocytes, and rates of in vitro maturation and apoptosis of human oocytes in relation to age. DESIGN:Prospective comparative study. SETTING:Reproductive medicine center. PATIENT(S):Women undergoing surgery for ovarian cysts. INTERVENTION(S):Oocytes were incub...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)01597-1
更新日期：2000-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the safety profile of endometrial ablation performed with a thermal balloon as defined by serosal temperature elevation and depth of injury. DESIGN:Observational study with histopathologic correlation conducted in ex vivo and in vivo phases. SETTING:Academic medical center. PATIENT(S):Twenty pa...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00245-3
更新日期：1998-10-01 00:00:00
abstract：:Tumor necrosis factor-alpha stimulates the secretion of vascular endothelial growth factor by cultured human oviductal epithelial cells and stromal fibroblasts. Tumor necrosis factor-alpha-stimulated vascular endothelial growth factor secretion by these cells may control oviductal fluid secretion by regulating vascula...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.05.082
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of vascular endothelial growth factor (VEGF) injection into the testes on spermatogenesis and apoptosis in a varicocele-induced adolescent rat model. SETTING:University hospital urology research laboratory. ANIMAL(S):Six-week-old male Wistar rats (n = 32). INTERVENTION:The rats we...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.06.008
更新日期：2009-05-01 00:00:00
abstract：:The histologic appearance of the testes of men exposed to chronic gonadotropin-releasing hormone agonist (GnRH-A) therapy has not been previously documented. Herein, we report on the histologic features of the testes of four patients with disseminated prostatic carcinoma who received at least 1 year of daily treatment...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48205-1
更新日期：1984-11-01 00:00:00
abstract：OBJECTIVE:To examine the effect of supraphysiologic doses of testosterone (T) on plasma total homocysteine (tHcy) concentrations in patients with Klinefelter's syndrome (KS). DESIGN:Prospective clinical study. SETTING:University hospital. PATIENT(S):Thirty-two newly diagnosed male patients with KS, and 20 healthy, v...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.11.029
更新日期：2004-05-01 00:00:00
abstract：:In a qualitative interview study of 77 families with stored frozen embryos, we found that while embryo disposition decision making was influenced by individual life circumstances, embryo quantity/quality, personal values, embryo conceptualization, and clinic information, it was a stepwise process that could be represe...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.06.027
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the extent to which test accuracy studies published in two leading reproductive medicine journals in the years 1999 and 2004 adhered to the Standards for Reporting of Diagnostic Accuracy (STARD) initiative parameters, and to explore whether the introduction of the STARD statement has led to an imp...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.03.050
更新日期：2006-11-01 00:00:00
abstract：:Clearly, to provide adequate counseling to women with POF, information is critically needed concerning the background incidence of spontaneous improvement in ovarian function as well as carefully designed, controlled studies to evaluate the efficacy of presumed therapeutic intervention. The case presented herein under...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53238-5
更新日期：1990-01-01 00:00:00
abstract：:Hysteroscopic examination of the uterine cavity revealed that patients previously treated for intramural myoma(s) by uterine artery embolization had a significantly higher incidence of abnormal findings compared with patients treated by laparoscopic occlusion of uterine arteries (59.5% vs. 2.7%). In particular, there ...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2010.12.014
更新日期：2011-05-01 00:00:00
abstract：:A direct assay for measuring sperm-associated immunoglobulin G (IgG) and an indirect assay for measuring IgG plasma antisperm antibodies were devised utilizing fluorescein-labeled antihuman IgG and a fluorescein-activated flow cytometer. The method singularly analyzed Ig attached to the surface of sperm because sperm ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48146-x
更新日期：1984-10-01 00:00:00
