Phagocytic activity of Dictyostelium amoebae treated with an organochlorine pesticide.

Abstract:

:The effect of an organochlorine pesticide benzene hexachloride (containing alpha, beta, gamma and delta isomers) on the phagocytic activity of the vegetative cells of Dictyostelium discoideum was investigated. Benzene hexachloride (BHC) at concentrations of 60 ppm and above inhibited the phagocytic activity as revealed by 3H-labelled E. coli uptake. The BHC treated cells also showed smaller and delayed plaque formation. Interactions of lipophilic pesticide with the hydrophobic cell surface presumably alters the receptor mediated phagocytosis of Dictyostelium amoebae.

journal_name

Cell Biol Int

authors

Gayatri R,Chatterjee S

doi

10.1006/cbir.1993.1071

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

349-52

issue

3

eissn

1065-6995

issn

1095-8355

pii

S1065-6995(83)71071-1

journal_volume

17

pub_type

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