Abstract:
:Serum levels of carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP) and beta-subunit of human chorionic gonadotropin (HCG) in coke oven workers were estimated in order to detect early biological effects of carcinogenesis. CEA, AFP and HCG concentrations were measured in 30 coke oven workers (group I) occupationally exposed to very high concentrations of BaP and tar substances. One of the control groups (group II) consisted of 64 inhabitants of a highly industrialized city whereas the second one comprised 35 persons living in a relatively unpolluted region (group III). Mean serum levels of CEA and AFP in group I were significantly higher than in the control groups. Furthermore, mean CEA level was significantly higher in group II than in group III. HCG concentrations only in a few cases exceeded the threshold of detectability. The effect of tobacco smoking was revealed only in the control groups. No correlation was found between the exposure time and the examined tumour marker levels. It is supposed that the obtained results were the consequence of enhanced expression of genes responsible for the markers synthesis, initiation of early stage of oncogenesis and were due to long-term exposure to carcinogenic PAHs.
journal_name
Med Prjournal_title
Medycyna pracyauthors
Snit Msubject
Has Abstractpub_date
1993-01-01 00:00:00pages
21-8issue
1eissn
0465-5893issn
2353-1339journal_volume
44pub_type
杂志文章相关文献
MEDYCYNA PRACY文献大全abstract::The examinations of methemoglobin and properdine levels as well as of the function of peripheral blood leukocytes in the tetranitrozolic blue reduction test (NBT) were performed in the exposed persons. The obtained results were compared with those of the control group, using statistical methods. It has been found that...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:The engagement of children in work is common in agricultural families. Work of children brings about cific benefits to both the family and the children; however, at the same time, it creates many hazards, including health risk. MATERIALS AND METHOD:The aim of the study was to determine current and delayed h...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract::It is well known that the employer bears the responsibility for all what is going on in every type of enterprise. Polish high schools (all types) do not provide future managers with full range of education as they do not teach their alumni about occupational medicine and hygiene. Curricula should include classes devot...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:To analyze occupational exposures to blood-borne pathogens among workers of a 130-bed hospital of surgical profile in the Małopolska province. MATERIAL AND METHODS:All cases of occupational exposure recorded in the hospital in the years 1998-2013 were analyzed, taking into account exposure rates (no. of inc...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::Five male volunteers were exposed to benzene vapour (100 mg X m-3) during 2 h singly and during 4 successive days. The mean retention of benzene in the lungs and mean dose amounted to 61% and 74 mg, respectively. Two phases of the excretion of unchanged benzene in the expired air (t 1/2 approximately 2 h and approxima...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Acrylamide is a synthetic chemical compound commonly used in many branches of industry. It is mainly used in the synthesis of polyacrylamides, which are widely employed in plastics, paints, varnishes, adhesives and mortars production. Acrylamide is also applied in the cellulose-paper and cosmetic industries to produce...
journal_title:Medycyna pracy
pub_type: 杂志文章,评审
doi:
更新日期:2013-01-01 00:00:00
abstract::Many women are exposed to carbon disulfide (C2) hazards at work every day. Working with C2 may cause some women to experience abnormalities in their reproductive health. Until now obtained data is generally concentrated on the health effects of C2 observed in the viscose industry. To date, C2 has not been studied prec...
journal_title:Medycyna pracy
pub_type: 杂志文章,评审
doi:10.13075/mp.5893.00600
更新日期:2018-05-22 00:00:00
abstract::In this paper basic issues concerning epidemiology of Lyme disease were presented. The role of ticks and small mammals was emphasised. An increasing prevalence of Lyme disease especially among people working in forests was pointed out. ...
journal_title:Medycyna pracy
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:To ensure the security for persons using the laboratory for research purposes it was decided to determine the influence of the number of employees and the time of their work on the survivability and vitality of Candida albicans, C. dubliniensis and C. tropicalis. MATERIAL AND METHODS:Working time and the nu...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Both ethylene and propylene glycol alkyl ethers (EGAEs and PGAEs, respectively) are widely used, mainly as solvents, in industrial and household products. Some EGAEs demonstrate gonadotoxic, embriotoxic, fetotoxic and teratogenic effects in both humans and experimental animals. Due to the noxious impact of these ether...
journal_title:Medycyna pracy
pub_type: 杂志文章,评审
doi:10.13075/mp.5893.00219
更新日期:2015-01-01 00:00:00
abstract::In Poland like in other European countries a favorable trend towards reducing morbidity and mortality from cardiovascular disease has been observed. Nevertheless they are still one of the most important health problems in the population, responsible for nearly half of all deaths, including premature deaths. They also ...
journal_title:Medycyna pracy
pub_type: 杂志文章,评审
doi:
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:In industrialized countries, diseases attributable to low physical activity form a very serious social and economic problem. MATERIALS AND METHODS:The aim of this study was to analyze the level of recreational physical activity in a random sample of 200 people at working age in Łódź. Physical activity was d...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::The Farnsworth-Munsell 100 Hue test was used to examine 75 males aged 25-60 years before and after a break in exposure to petroleum derivatives and 30 males non-occupationally involved in the petrochemical industry. Acquired colour vision disturbances were found in 29% of those under study before and in 16% after a br...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:The whole spectrum of disorders of the hematopoietic tissue, eye and skin induced by ionizing radiation covers complex pathologies termed as a postirradiation syndrome, as well as various malignancies. The aim of this work is to present the data on incidence of occupational diseases with ionizing radiation a...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::The aim of the study was to assess the role of bronchial hyperreactivity in the development of chronic airflow obstruction in the population of the Bogdanka (Lublin Basin) coal miners. The population examined consisted of 1456 coal miners working underground in the Bogdanka colliery. The methods of the study included ...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Perchloroethylene is used mainly as a solvent in dry cleaning, cleaning of electrical equipment, and degreasing of metal parts. The authors report a case of acute poisoning with perchloroethylene contracted by a maintenance worker when cleaning an electric transformer. Since perchloroethylene may cause severe poisonin...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:10.13075/mp.5893.00778
更新日期:2019-06-14 00:00:00
abstract::A long-lasting exposure to lead and cadmium may cause changes in the immune response. Until now only a few reports have addressed this problem. At present, the direct immunotoxicity of heavy metals is the subject of extensive studies, especially on in vitro models. Heavy metals may regulate the immune response of the ...
journal_title:Medycyna pracy
pub_type: 杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::Oral glucose test and serum insulin determination was performed in 192 workers of a large metallurgical factory. The subjects were divided into four groups: 1. exposed to isolated noise, 2. exposed to local vibration, 3. exposed to the whole body vibration, and 4. control group. In the group exposed to the whole body ...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Automotive ignition system diagnostic procedures involve a specific kind of action due to the presence of high voltage pulses rated of roughly several dozen kilovolts. Therefore, the repairers employed at car service coming into direct contact with electrical equipment of ignition systems are exposed to risk of electr...
journal_title:Medycyna pracy
pub_type: 杂志文章,评审
doi:
更新日期:2014-01-01 00:00:00
abstract::Social acceptance of periodical examinations was evaluated via a survey conducted among a group of 530 machine industry workers. A questionnaire for prophylactic examinations was used which was worked out at the Department of Epidemiology and Statistics of the Nofer Institute of Occupational Medicine in Lódź, with add...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::A group under study embraced 73 workers involved in the production of acetic aldehyde, 74 workers of the department of chlorine and 13 retired workers with past poisoning by mercury. The control group consisted of 40 persons. Examinations performed in all subjects were designed mainly to assess the kidney lesions. The...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:In view of the aging process in our population there is a need to identify effective methods to prevent disadvantageous effects of this trend. In this paper the state of particular health-related behaviors and elements of health awareness among retirement-approaching employees are presented as a basis for de...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Chronic occupational or environmental exposure to small doses of lead results in cardiovascular disorders: arterial hypertension, lipid metabolism disturbances and exacerbation of free radical processes. Each of these changes determines an independent cardiovascular risk factor. The aim of this study was to ...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::This paper discusses occupational exposure to chemical carcinogens in Poland in 2001 based on data obtained from the Central Register of Carcinogen Agents (CRCA). The data on 3017 enterprises, in which employees were exposed to chemical carcinogens (chemicals, mixtures and technological processes involving carcinogeni...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the association between night shift work and the prevalence of diseases and conditions among nurses and midwives. MATERIAL AND METHODS:The study included 725 subjects (354 working on night shifts and 371 working only during the day). The data were collected via an intervi...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Asbestos dust is one of the most dangerous pneumoconiotic and carcinogenic agents. The aim of this study was to assess the occurrence of asbestosis and pleural mesothelioma, depending on asbestos consumption and the type of manufactured products, among former asbestos workers in Poland. MATERIAL AND METHODS...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The aim of the study was to answer the question what is the audibility area of auditory danger signal emitted by an industrial truck in the noisy environment. MATERIAL AND METHODS:The sound pressure level of the signal produced by the truck horn was measured in 12 directions around the truck, at a distance ...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:10.13075/mp.5893.00132
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Industrial development increases the threat to human health caused by chemical contamination of the environment. Occupational neoplasms induced by exposure to carcinogenic factors present in workplaces are one of its effects. Heavy metals, especially arsenic, play an important role in this process. The aim o...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::The aim of the study was to assess in vitro the effect of electromagnetic field produced by mobile phones on the activity of superoxide dismutase (SOD-1) and the level of malonyldialdehyde (MDA) in human blood platelets. The suspension of blood platelets was exposed to the electromagnetic field with the frequency of 9...
journal_title:Medycyna pracy
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::This is a methodology paper--it contains a review of different quantitative risk assessment methods and their comparison. There are two aspects of cancer risk modeling discussed here: 1. When there is one effective dose only. There were compared two models in this evaluation: one proposed by the Dutch Expert Committee...
journal_title:Medycyna pracy
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00