[Concentration of carcinoembryonic antigen, alpha-fetoprotein and beta-subunit of human chorionic gonadotropin in serum of workers employed directly in the production of coke].

Abstract:

:Serum levels of carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP) and beta-subunit of human chorionic gonadotropin (HCG) in coke oven workers were estimated in order to detect early biological effects of carcinogenesis. CEA, AFP and HCG concentrations were measured in 30 coke oven workers (group I) occupationally exposed to very high concentrations of BaP and tar substances. One of the control groups (group II) consisted of 64 inhabitants of a highly industrialized city whereas the second one comprised 35 persons living in a relatively unpolluted region (group III). Mean serum levels of CEA and AFP in group I were significantly higher than in the control groups. Furthermore, mean CEA level was significantly higher in group II than in group III. HCG concentrations only in a few cases exceeded the threshold of detectability. The effect of tobacco smoking was revealed only in the control groups. No correlation was found between the exposure time and the examined tumour marker levels. It is supposed that the obtained results were the consequence of enhanced expression of genes responsible for the markers synthesis, initiation of early stage of oncogenesis and were due to long-term exposure to carcinogenic PAHs.

journal_name

Med Pr

journal_title

Medycyna pracy

authors

Snit M

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

21-8

issue

1

eissn

0465-5893

issn

2353-1339

journal_volume

44

pub_type

杂志文章
  • [Non-specific immunity of persons exposed to contaminants emitted by nitrogen plants].

    abstract::The examinations of methemoglobin and properdine levels as well as of the function of peripheral blood leukocytes in the tetranitrozolic blue reduction test (NBT) were performed in the exposed persons. The obtained results were compared with those of the control group, using statistical methods. It has been found that...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Kośmider S,Misiewicz A,Kubek A

    更新日期:1977-01-01 00:00:00

  • [Effects of work in childhood on health in the opinion of respondents from agricultural families].

    abstract:BACKGROUND:The engagement of children in work is common in agricultural families. Work of children brings about cific benefits to both the family and the children; however, at the same time, it creates many hazards, including health risk. MATERIALS AND METHOD:The aim of the study was to determine current and delayed h...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Lachowski S,Florek-Luszczki M

    更新日期:2013-01-01 00:00:00

  • [Undergraduate and postgraduate training in occupational hygiene (and medicine) during non-medical studies].

    abstract::It is well known that the employer bears the responsibility for all what is going on in every type of enterprise. Polish high schools (all types) do not provide future managers with full range of education as they do not teach their alumni about occupational medicine and hygiene. Curricula should include classes devot...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Szozda R

    更新日期:2002-01-01 00:00:00

  • [Analysis of occupational exposure of healthcare workers in the years 1998-2013 for bloodborne pathogens on the example of the hospital of the surgical profile].

    abstract:BACKGROUND:To analyze occupational exposures to blood-borne pathogens among workers of a 130-bed hospital of surgical profile in the Małopolska province. MATERIAL AND METHODS:All cases of occupational exposure recorded in the hospital in the years 1998-2013 were analyzed, taking into account exposure rates (no. of inc...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Szczypta A,Różańska A,Bulanda M

    更新日期:2014-01-01 00:00:00

  • [Toxicokinetics of benzene in humans. Excretion of phenol with urine and benzene with expired air after single and 4-day inhalation exposure].

    abstract::Five male volunteers were exposed to benzene vapour (100 mg X m-3) during 2 h singly and during 4 successive days. The mean retention of benzene in the lungs and mean dose amounted to 61% and 74 mg, respectively. Two phases of the excretion of unchanged benzene in the expired air (t 1/2 approximately 2 h and approxima...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Paradowski M,Jakubowski M,Podoski A

    更新日期:1984-01-01 00:00:00

  • [Toxicity of acrylamide and its metabolite - glicydamide].

    abstract::Acrylamide is a synthetic chemical compound commonly used in many branches of industry. It is mainly used in the synthesis of polyacrylamides, which are widely employed in plastics, paints, varnishes, adhesives and mortars production. Acrylamide is also applied in the cellulose-paper and cosmetic industries to produce...

    journal_title:Medycyna pracy

    pub_type: 杂志文章,评审

    doi:

    authors: Pingot D,Pyrzanowski K,Michałowicz J,Bukowska B

    更新日期:2013-01-01 00:00:00

  • Health effect of chronic exposure to carbon disulfide (C2) on women employed in viscose industry.

    abstract::Many women are exposed to carbon disulfide (C2) hazards at work every day. Working with C2 may cause some women to experience abnormalities in their reproductive health. Until now obtained data is generally concentrated on the health effects of C2 observed in the viscose industry. To date, C2 has not been studied prec...

    journal_title:Medycyna pracy

    pub_type: 杂志文章,评审

    doi:10.13075/mp.5893.00600

    authors: Sieja K,von Mach-Szczypiński J,von Mach-Szczypiński J

    更新日期:2018-05-22 00:00:00

  • [Epidemiology of Lyme borreliosis].

    abstract::In this paper basic issues concerning epidemiology of Lyme disease were presented. The role of ticks and small mammals was emphasised. An increasing prevalence of Lyme disease especially among people working in forests was pointed out. ...

    journal_title:Medycyna pracy

    pub_type: 杂志文章,评审

    doi:

    authors: Pancewicz SA,Kondrusik M,Zajkowska J,Hermanowska-Szpakowicz T

    更新日期:1999-01-01 00:00:00

  • [Survivability of Candida fungi and workpost safety in the university mycological laboratory].

    abstract:BACKGROUND:To ensure the security for persons using the laboratory for research purposes it was decided to determine the influence of the number of employees and the time of their work on the survivability and vitality of Candida albicans, C. dubliniensis and C. tropicalis. MATERIAL AND METHODS:Working time and the nu...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Ejdys E

    更新日期:2009-01-01 00:00:00

  • [Ethylene glycol and propylene glycol ethers - Reproductive and developmental toxicity].

    abstract::Both ethylene and propylene glycol alkyl ethers (EGAEs and PGAEs, respectively) are widely used, mainly as solvents, in industrial and household products. Some EGAEs demonstrate gonadotoxic, embriotoxic, fetotoxic and teratogenic effects in both humans and experimental animals. Due to the noxious impact of these ether...

    journal_title:Medycyna pracy

    pub_type: 杂志文章,评审

    doi:10.13075/mp.5893.00219

    authors: Starek-Świechowicz B,Starek A

    更新日期:2015-01-01 00:00:00

  • [Rare cardiovascular diseases in the context of occupational health care].

    abstract::In Poland like in other European countries a favorable trend towards reducing morbidity and mortality from cardiovascular disease has been observed. Nevertheless they are still one of the most important health problems in the population, responsible for nearly half of all deaths, including premature deaths. They also ...

    journal_title:Medycyna pracy

    pub_type: 杂志文章,评审

    doi:

    authors: Salska A,Chiżyński K,Salski W,Wiszniewska M,Walusiak-Skorupa J

    更新日期:2014-01-01 00:00:00

  • [Leisure time activity in a random sample of working-age people in Lodz--preliminary results].

    abstract:BACKGROUND:In industrialized countries, diseases attributable to low physical activity form a very serious social and economic problem. MATERIALS AND METHODS:The aim of this study was to analyze the level of recreational physical activity in a random sample of 200 people at working age in Łódź. Physical activity was d...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Kaleta D,Jegier A

    更新日期:2003-01-01 00:00:00

  • [Acquired color vision disturbances as a sensitive marker of chronic exposure to petroleum derivatives].

    abstract::The Farnsworth-Munsell 100 Hue test was used to examine 75 males aged 25-60 years before and after a break in exposure to petroleum derivatives and 30 males non-occupationally involved in the petrochemical industry. Acquired colour vision disturbances were found in 29% of those under study before and in 16% after a br...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Zdzieszyńska M,Goś R

    更新日期:1995-01-01 00:00:00

  • [Occupational diseases caused by ionizing radiation in Poland, 1971-2006].

    abstract:BACKGROUND:The whole spectrum of disorders of the hematopoietic tissue, eye and skin induced by ionizing radiation covers complex pathologies termed as a postirradiation syndrome, as well as various malignancies. The aim of this work is to present the data on incidence of occupational diseases with ionizing radiation a...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Wilczyńska U,Szeszenia-Dabrowska N

    更新日期:2008-01-01 00:00:00

  • [Bronchial hyperreactivity as a factors of chronic obstructive pulmonary disease development in the population of the Bogdanka coal miners].

    abstract::The aim of the study was to assess the role of bronchial hyperreactivity in the development of chronic airflow obstruction in the population of the Bogdanka (Lublin Basin) coal miners. The population examined consisted of 1456 coal miners working underground in the Bogdanka colliery. The methods of the study included ...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Mosiewicz J,Myśliński W,Ryczak E,Dzida G,Biłan A,Palusiński R,Hanzlik J

    更新日期:1999-01-01 00:00:00

  • Perchloroethylene: acute occupational poisoning and a proposal for its replacement with other less toxic substances.

    abstract::Perchloroethylene is used mainly as a solvent in dry cleaning, cleaning of electrical equipment, and degreasing of metal parts. The authors report a case of acute poisoning with perchloroethylene contracted by a maintenance worker when cleaning an electric transformer. Since perchloroethylene may cause severe poisonin...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:10.13075/mp.5893.00778

    authors: Sanz-Gallen P,Sanz-Ribas A,Martí-Amengual G,Fernández-Colomé J

    更新日期:2019-06-14 00:00:00

  • [The impact of lead and cadmium on the immune system].

    abstract::A long-lasting exposure to lead and cadmium may cause changes in the immune response. Until now only a few reports have addressed this problem. At present, the direct immunotoxicity of heavy metals is the subject of extensive studies, especially on in vitro models. Heavy metals may regulate the immune response of the ...

    journal_title:Medycyna pracy

    pub_type: 杂志文章,评审

    doi:

    authors: Skoczyńska A,Poreba R,Sieradzki A,Andrzejak R,Sieradzka U

    更新日期:2002-01-01 00:00:00

  • [Glucose tolerance test and insulinemia in workers occupationally exposed to vibration and noise].

    abstract::Oral glucose test and serum insulin determination was performed in 192 workers of a large metallurgical factory. The subjects were divided into four groups: 1. exposed to isolated noise, 2. exposed to local vibration, 3. exposed to the whole body vibration, and 4. control group. In the group exposed to the whole body ...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Wegiel A,Pigoń-Wegiel A,Pluskiewicz K

    更新日期:1993-01-01 00:00:00

  • [Exposure to electrocution by automotive ignition system in the work environment of car service employees].

    abstract::Automotive ignition system diagnostic procedures involve a specific kind of action due to the presence of high voltage pulses rated of roughly several dozen kilovolts. Therefore, the repairers employed at car service coming into direct contact with electrical equipment of ignition systems are exposed to risk of electr...

    journal_title:Medycyna pracy

    pub_type: 杂志文章,评审

    doi:

    authors: Fryśkowski B,Swiatek-Fryśkowska D

    更新日期:2014-01-01 00:00:00

  • [Study of social acceptance of periodic examinations by machine industry workers].

    abstract::Social acceptance of periodical examinations was evaluated via a survey conducted among a group of 530 machine industry workers. A questionnaire for prophylactic examinations was used which was worked out at the Department of Epidemiology and Statistics of the Nofer Institute of Occupational Medicine in Lódź, with add...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Leszczyńska K

    更新日期:1990-01-01 00:00:00

  • [Examination of health effects from exposure to metallic mercury in workers employed in production of chlorine and aldehyde. II. Assessment of kidney lesions].

    abstract::A group under study embraced 73 workers involved in the production of acetic aldehyde, 74 workers of the department of chlorine and 13 retired workers with past poisoning by mercury. The control group consisted of 40 persons. Examinations performed in all subjects were designed mainly to assess the kidney lesions. The...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Marek K,Wocka-Marek T,Zajac-Nedza M,Rola E,Zejda J,Kochańska-Dziurowicz A,Smolicha W

    更新日期:1995-01-01 00:00:00

  • [Health beliefs and health behavior in older employees of medium-size and large enterprises].

    abstract:BACKGROUND:In view of the aging process in our population there is a need to identify effective methods to prevent disadvantageous effects of this trend. In this paper the state of particular health-related behaviors and elements of health awareness among retirement-approaching employees are presented as a basis for de...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Korzeniowska E

    更新日期:2004-01-01 00:00:00

  • [Risk of cadrdiovascular diseases in lead-exposed workers of crystal glassworks. Part I. Effect of lead on blood pressure and lipid metabolism].

    abstract:BACKGROUND:Chronic occupational or environmental exposure to small doses of lead results in cardiovascular disorders: arterial hypertension, lipid metabolism disturbances and exacerbation of free radical processes. Each of these changes determines an independent cardiovascular risk factor. The aim of this study was to ...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Skoczyńska A,Gruber K,Belowska-Bień K,Mlynek V

    更新日期:2007-01-01 00:00:00

  • [Occupational exposure to chemical carcinogens in Poland, 2001].

    abstract::This paper discusses occupational exposure to chemical carcinogens in Poland in 2001 based on data obtained from the Central Register of Carcinogen Agents (CRCA). The data on 3017 enterprises, in which employees were exposed to chemical carcinogens (chemicals, mixtures and technological processes involving carcinogeni...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Konieczko K,Czerczak S,Kluszczyński D

    更新日期:2004-01-01 00:00:00

  • Night work and health status of nurses and midwives. cross-sectional study.

    abstract:BACKGROUND:The aim of this study was to assess the association between night shift work and the prevalence of diseases and conditions among nurses and midwives. MATERIAL AND METHODS:The study included 725 subjects (354 working on night shifts and 371 working only during the day). The data were collected via an intervi...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Burdelak W,Bukowska A,Krysicka J,Pepłońska B

    更新日期:2012-01-01 00:00:00

  • Asbestos related diseases among workers of asbestos processing plants in relation to type of production and asbestos use.

    abstract:BACKGROUND:Asbestos dust is one of the most dangerous pneumoconiotic and carcinogenic agents. The aim of this study was to assess the occurrence of asbestosis and pleural mesothelioma, depending on asbestos consumption and the type of manufactured products, among former asbestos workers in Poland. MATERIAL AND METHODS...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Szeszenia-Dąbrowska N,Świątkowska B,Sobala W,Szubert Z,Wilczyńska U

    更新日期:2015-01-01 00:00:00

  • [ASSESSMENT OF THE AUDIBILITY AREA OF AUDITORY DANGER SIGNALS PRODUCED BY INDUSTRIAL TRUCK].

    abstract:BACKGROUND:The aim of the study was to answer the question what is the audibility area of auditory danger signal emitted by an industrial truck in the noisy environment. MATERIAL AND METHODS:The sound pressure level of the signal produced by the truck horn was measured in 12 directions around the truck, at a distance ...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:10.13075/mp.5893.00132

    authors: Młyński R,Kozłowski E

    更新日期:2015-01-01 00:00:00

  • [Plasma concentration of selected neoplastic markers in persons occupationally exposed to arsenic and heavy metals].

    abstract:BACKGROUND:Industrial development increases the threat to human health caused by chemical contamination of the environment. Occupational neoplasms induced by exposure to carcinogenic factors present in workplaces are one of its effects. Heavy metals, especially arsenic, play an important role in this process. The aim o...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Szymańska-Chabowska A,Antonowicz-Juchniewicz J,Andrzejak R

    更新日期:2004-01-01 00:00:00

  • [Effect of electromagnetic field produced by mobile phones on the activity of superoxide dismutase (SOD-1) and the level of malonyldialdehyde (MDA)--in vitro study].

    abstract::The aim of the study was to assess in vitro the effect of electromagnetic field produced by mobile phones on the activity of superoxide dismutase (SOD-1) and the level of malonyldialdehyde (MDA) in human blood platelets. The suspension of blood platelets was exposed to the electromagnetic field with the frequency of 9...

    journal_title:Medycyna pracy

    pub_type: 杂志文章

    doi:

    authors: Stopczyk D,Gnitecki W,Buczyński A,Markuszewski L,Buczyński J

    更新日期:2002-01-01 00:00:00

  • [Quantitative methods of cancer risk assessment in exposure to chemicals].

    abstract::This is a methodology paper--it contains a review of different quantitative risk assessment methods and their comparison. There are two aspects of cancer risk modeling discussed here: 1. When there is one effective dose only. There were compared two models in this evaluation: one proposed by the Dutch Expert Committee...

    journal_title:Medycyna pracy

    pub_type: 杂志文章,评审

    doi:

    authors: Szymczak W

    更新日期:2009-01-01 00:00:00