Circadian rhythms of thyroid secretion, morphometry, and cell division in prometamorphic and climax Rana tadpoles.

Abstract:

:Rhythmicity of thyroid follicle structure, cell division, and T4 secretion in vitro was studied in anuran tadpoles on a 12L:12D cycle with light onset at 0800 hr. Stage XIII Rana pipiens larvae had a significant circadian rhythm of follicle lumen diameter (acrophase 1052 hr). Follicle cell height was higher at 0900 hr than at other times but the rhythm was not significant. At Stage XX, both follicle cell height (acrophase 2318 hr) and cell division (acrophase 1929 hr) were rhythmic while lumen diameter, though highest at 0900 hr, showed no significant daily changes. Thyroids from Rana catesbeiana larvae at Stages XVII to XVIII had a significant circadian rhythm of T4 secretion (acrophase 2034 hr) in vitro as measured by radioimmunoassay of media collected every 6 hr for 24 hr. The findings indicate that the daily sequence of thyroid structure and function in preclimax Rana tadpoles includes larger follicle lumina early in the light and maximum cell division, T4 secretion, and follicle cell height within a 4-hr interval beginning around the onset of dark.

journal_name

Gen Comp Endocrinol

authors

Wright ML,Blanchard LS,Pikula A,Labieniec KE

doi

10.1006/gcen.1995.1087

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

75-84

issue

1

eissn

0016-6480

issn

1095-6840

pii

S0016-6480(85)71087-8

journal_volume

99

pub_type

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