Abstract：
:Change in PO2 in endolymph, endocochlear potentials and cochlear microphonics have been tested in normoxia, hyperoxia and anoxia on 24 guinea pigs. The polarographic method and construction of oxygen-sensitive microelectrodes is described in detail. The normal level of PO2 in endolymph vaires between 20 and 30 mm Hg. One-minute anoxia induced by breathing 100% N2 caused a decline in PO2, EP and CM, but during recovery only PO2 returned with over-correction to the preexposure level. Hyperoxia evoked by breathing 100% oxygen failed to increase the cochlear potentials and the PO2 in the endolymph. This suggests that vasoconstriction most likely occurs proximal to the capillaries bed of the stria vascularis.
journal_name
Hear Resjournal_title
Hearing researchauthors
Prazma J,Fischer ND,Biggers WP,Ascher Ddoi
10.1016/0378-5955(78)90003-5subject
Has Abstractpub_date
1978-10-01 00:00:00pages
3-9issue
1eissn
0378-5955issn
1878-5891pii
0378-5955(78)90003-5journal_volume
1pub_type
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