Plasma levels of VLDL- + LDL-cholesterol, HDL-cholesterol, triglycerides and apoproteins B and A-I in a healthy population--influence of several risk factors.

Abstract:

:Plasma apo B and apo A-I were determined in 477 subjects (206 males and 271 females) by laser immuno-nephelometry. Measurements of VLDL- + LDL-cholesterol, HDL-cholesterol and triglycerides were done simultaneously. VLDL- + LDL-cholesterol and apo B values were similar in males and females and increased with age. HDL-cholesterol and apo A-I values were higher in females but stable with age. Different regression curves (HDL-cholesterol vs apo A-I) were obtained in males and females and a negative correlation was found between HDL-cholesterol or apo A-I and triglycerides. Increased body weight was associated with higher values of VLDL- + LDL-cholesterol, apo B and triglycerides in both sexes but lower values of HDL-cholesterol and apo A-I essentially in males. Finally, the study provides evidence of a relationship between smoking and alcohol consumption on the one hand, and HDL-cholesterol and apo A-I on the other.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Dedonder-Decoopman E,Fievet-Desreumaux C,Campos E,Moulin S,Dewailly P,Sezille G,Jaillard J

doi

10.1016/0021-9150(80)90063-5

subject

Has Abstract

pub_date

1980-12-01 00:00:00

pages

559-68

issue

4

eissn

0021-9150

issn

1879-1484

pii

0021-9150(80)90063-5

journal_volume

37

pub_type

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