The structure of histone H1 and its location in chromatin.

Abstract:

:On the basis of their primary structure, the lysine-rich histones are a unified family of proteins. Each has an amino acid chain which falls into three distinct domains. Only the central domain (approximately 80 residues) is in a folded conformation. It is protected from trypsin digestion in chromatin and corresponds to the segment of highest sequence conservation. Without the flanking domains it is able to close two full turns of DNA in the nucleosome and can thus locate the H1 molecule.

journal_name

Nature

journal_title

Nature

authors

Allan J,Hartman PG,Crane-Robinson C,Aviles FX

doi

10.1038/288675a0

subject

Has Abstract

pub_date

1980-12-25 00:00:00

pages

675-9

issue

5792

eissn

0028-0836

issn

1476-4687

journal_volume

288

pub_type

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