Abstract:
:On the basis of their primary structure, the lysine-rich histones are a unified family of proteins. Each has an amino acid chain which falls into three distinct domains. Only the central domain (approximately 80 residues) is in a folded conformation. It is protected from trypsin digestion in chromatin and corresponds to the segment of highest sequence conservation. Without the flanking domains it is able to close two full turns of DNA in the nucleosome and can thus locate the H1 molecule.
journal_name
Naturejournal_title
Natureauthors
Allan J,Hartman PG,Crane-Robinson C,Aviles FXdoi
10.1038/288675a0subject
Has Abstractpub_date
1980-12-25 00:00:00pages
675-9issue
5792eissn
0028-0836issn
1476-4687journal_volume
288pub_type
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