Fundic inhibition of acid secretion and gastrin release in the dog.

abstract：:Obstruction of the common bile duct can now be relieved by endoscopic electrosurgery. This report describes our experience with 267 patients. In 192 of 222 patients with choledocholithiasis all calculi were evacuated by endoscopic papillotomy (EP). The remaining patients had EP because of papillary stenosis. Complicat...

journal_title：Gastroenterology

authors： Koch H,Rösch W,Schaffner O,Demling L

更新日期：1977-12-01 00:00:00

abstract：:Using flowing isotonic NaCl or flowing molar KCl electrodes, the magnitude of liquid junction potentials between the electrode tip and gastric juice was measured directly, and calculated from electrolyte concentrations in gastric juice according to standard formulas. Gastric transepithelial potential difference was ob...

journal_title：Gastroenterology

authors： Read NW,Fordtran JS

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND & AIMS:Long-term data on the risk of colorectal cancer according to dose, duration, and consistency of aspirin therapy are limited. METHODS:We conducted a prospective study of 47,363 male health professionals who were ages 40-75 years at enrollment in 1986. Biennially, we collected data on aspirin use, othe...

journal_title：Gastroenterology

authors： Chan AT,Giovannucci EL,Meyerhardt JA,Schernhammer ES,Wu K,Fuchs CS

更新日期：2008-01-01 00:00:00

abstract：:Peptic digestion of gluten results in the production of substances having opiatelike activity in bio- and receptor assays. These substances have been termed exorphins. In this study, we determined the effect of gluten, hydrolyzed gluten, and hydrolyzed gluten plus the opiate blocker naloxone on a variety of hormonal p...

journal_title：Gastroenterology

authors： Morley JE,Levine AS,Yamada T,Gebhard RL,Prigge WF,Shafer RB,Goetz FC,Silvis SE

更新日期：1983-06-01 00:00:00

abstract：:Superficially invasive squamous cell carcinoma of the esophagus, defined as carcinoma with invasion limited to the mucosa or submucosa regardless of the presence of lymph node metastasis, is being increasingly recognized. We found 7 cases (13%) of this entity among 54 cases of esophageal squamous cancer resected betwe...

journal_title：Gastroenterology

authors： Schmidt LW,Dean PJ,Wilson RT

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND & AIMS:Intestinal fibrosis and stricture formation are serious complications of Crohn's disease, often requiring surgical intervention. Unfortunately, the mechanisms underlying intestinal fibrosis development are poorly understood, in part because of the lack of relevant animal models. Here, we present a nov...

journal_title：Gastroenterology

authors： Grassl GA,Valdez Y,Bergstrom KS,Vallance BA,Finlay BB

更新日期：2008-03-01 00:00:00

abstract：:Hepatitis B virus (HBV) and hepatitis C virus (HCV) cause 1.3 million deaths annually. To prevent more than 7 million deaths by 2030, the World Health Organization set goals to eliminate HBV and HCV, defined as a 90% reduction in new infections and a 65% reduction in deaths, and prevent more than 7 million related dea...

journal_title：Gastroenterology

authors： Ward JW,Hinman AR

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Platelets show proinflammatory as well as prothrombotic properties. Patients with inflammatory bowel disease are at increased risk of systemic thromboembolism, and multifocal microvascular infarction has been proposed as a pathogenetic mechanism in Crohn's disease. The aim of this study was to determine...

journal_title：Gastroenterology

authors： Collins CE,Cahill MR,Newland AC,Rampton DS

更新日期：1994-04-01 00:00:00

abstract：:A case of acute bacterial endocarditis is presented in which gallbladder infarction and areas of hepatic infarction were documented. Selective angiography showed findings consistent with emboli to the gallbladder and hepatic circulations. ...

journal_title：Gastroenterology

authors： Henrich WL,Huehnegarth RJ,Rösch J,Melnyk CS

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with irritable bowel syndrome with diarrhea (IBS-D) have increased mucosal serotonin (5-hydroxytryptamine [5-HT]) availability, possibly because immune activation reduces activity of the 5-HT transporter (SERT). We investigated the relationship between mucosal and platelet SERT and immune act...

journal_title：Gastroenterology

authors： Foley S,Garsed K,Singh G,Duroudier NP,Swan C,Hall IP,Zaitoun A,Bennett A,Marsden C,Holmes G,Walls A,Spiller RC

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND & AIMS:Regulation of blood flow and oxygen supply are important pathogenetic factors in alcoholic liver disease. Because nitric oxide may have an important role, its effects on alcoholic liver injury were investigated. METHODS:Rats were fed ethanol intragastrically with either saturated fat or corn oil. Spo...

journal_title：Gastroenterology

authors： Nanji AA,Greenberg SS,Tahan SR,Fogt F,Loscalzo J,Sadrzadeh SM,Xie J,Stamler JS

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND & AIMS:The comparative effectiveness of sigmoidoscopy and fecal immunochemical testing (FIT) for colorectal cancer (CRC) screening is unknown. METHODS:Individuals aged 50-74 years living in Southeast Norway were randomly invited between 2012 and 2019 to either once-only flexible sigmoidoscopy or FIT screeni...

journal_title：Gastroenterology

authors： Randel KR,Schult AL,Botteri E,Hoff G,Bretthauer M,Ursin G,Natvig E,Berstad P,Jørgensen A,Sandvei PK,Olsen ME,Frigstad SO,Darre-Næss O,Norvard ER,Bolstad N,Kørner H,Wibe A,Wensaas KA,de Lange T,Holme Ø

更新日期：2020-11-21 00:00:00

abstract：:Methylbenzylnitrosamine is an esophageal-specific carcinogen in the rat, and the incidence of methylbenzylnitrosamine-induced esophageal carcinoma is increased by dietary zinc deficiency. Methylbenzylnitrosamine requires activation by cytochrome P-450 to be mutagenic; the present study examined the role of dietary zin...

journal_title：Gastroenterology

authors： Barch DH,Fox CC,Rosche WA,Rundhaugen LM,Wrighton SA

更新日期：1992-09-01 00:00:00

abstract：:Morphologic and physiologic experiments in rodents have demonstrated differences between jejunal and ileal fat absorption. Compared with the rat jejunum, absorbed lipid particles within rat ileal absorptive cells are larger and exit at a slower rate. To evaluate the relevance of these observations to humans, we studie...

journal_title：Gastroenterology

authors： Surawicz CM,Levine DS,Saunders DR,Rubin CE

更新日期：1988-06-01 00:00:00

abstract：:We have investigated the effect of oral cisapride (10 mg t.i.d.) in a double-blind, placebo-controlled trial in 26 patients with upper gut dysmotility: 11 with gastroparesis (8 diabetic, 3 idiopathic) and 15 with chronic idiopathic intestinal pseudoobstruction. Patients were evaluated at entry and at the end of the 6-...

journal_title：Gastroenterology

authors： Camilleri M,Malagelada JR,Abell TL,Brown ML,Hench V,Zinsmeister AR

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND/AIMS:Recent in vivo studies using proton magnetic resonance (1H-MR) spectroscopy showed low levels of myo-inositol in the brain in hepatic encephalopathy; the pathogenetic relevance of this observation is unclear. METHODS:Myo-inositol and glutamine levels in the brain were studied in vivo by 1H-MR spectrosc...

journal_title：Gastroenterology

authors： Häussinger D,Laubenberger J,vom Dahl S,Ernst T,Bayer S,Langer M,Gerok W,Hennig J

更新日期：1994-11-01 00:00:00

abstract：:Because the esophagus is easily accessible with endoscopy, early diagnosis and curative treatment of esophageal cancer is possible. However, diagnosis is often delayed because symptoms are not specific during early stages of tumor development. The onset of dysphagia is associated with advanced disease, which has a sur...

journal_title：Gastroenterology

authors： di Pietro M,Canto MI,Fitzgerald RC

更新日期：2018-01-01 00:00:00

abstract：:This document presents the official recommendations of the American Gastroenterological Association (AGA) Institute on "Use of Gastrointestinal Medications in Pregnancy." It was approved by the Clinical Practice and Economics Committee on February 22, 2006, and by the AGA Institute Governing Board on April 20, 2006. ...

journal_title：Gastroenterology

authors： Mahadevan U,Kane S

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND & AIMS:It is unclear whether genomic derangement precedes the histological development of dysplasia in ulcerative colitis (UC)-related neoplastic progression. The primary aim of this study was to determine if chromosomal alterations occur early in the progression pathway of UC-related neoplasia. METHODS:Flu...

journal_title：Gastroenterology

authors： Willenbucher RF,Zelman SJ,Ferrell LD,Moore DH 2nd,Waldman FM

更新日期：1997-09-01 00:00:00

abstract：:To understand mechanisms of viral diarrhea further, we studied ileal ion transport in vitro in relation to mucosal changes and epithelial differentiation in transmissible gastroenteritis in piglets, an invasive viral enteritis thought to involve mainly proximal intestine. In infected pigs, at the height of diarrhea, s...

journal_title：Gastroenterology

authors： Shepherd RW,Gall DG,Butler DG,Hamilton JR

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND & AIMS:Rabs are monomeric guanosine triphosphatases that regulate membrane trafficking and acid secretion in gastric parietal cells. Using a proteomics approach, we identified a new Rab, Rab27b, in tubulovesicle membranes and determined its role in parietal cell activation. METHODS:We used mass spectrometry...

journal_title：Gastroenterology

authors： Suda J,Zhu L,Okamoto CT,Karvar S

更新日期：2011-03-01 00:00:00

abstract：:One hundred symptomatic patients with radiolucent gallbladder stones were treated with a new piezoelectric lithotripter and oral chemolitholytic agents. Stone disintegration was achieved in 99 of these patients (99%) with a mean (+/- SD) maximum fragment size of 5.1 +/- 4.1 mm. Significant differences were found when ...

journal_title：Gastroenterology

authors： Ell C,Kerzel W,Schneider HT,Benninger J,Wirtz P,Domschke W,Hahn EG

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND & AIMS:Galectins are beta-galactoside-binding proteins possibly involved in tumor progression. The aim of this study was to determine the pattern of galectin 3 and galectin 1 expression and involvement in colorectal cancer progression. METHODS:Galectin 3 expression was examined immunohistochemically in 39 s...

journal_title：Gastroenterology

authors： Sanjuán X,Fernández PL,Castells A,Castronovo V,van den Brule F,Liu FT,Cardesa A,Campo E

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND & AIMS:No controlled trial has examined the clinical efficacy of antibiotics in small bowel bacterial overgrowth. METHODS:Ten patients with bacterial overgrowth-related diarrhea underwent the following five 7-day treatment periods: untreated (control period), then placebo, and subsequently, in random order ...

journal_title：Gastroenterology

authors： Attar A,Flourié B,Rambaud JC,Franchisseur C,Ruszniewski P,Bouhnik Y

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND & AIMS:We have few population-level data on the performance of endoscopic retrograde cholangiopancreatography (ERCP) in the United States. We investigated the numbers of unplanned hospital encounters (UHEs), patient and facility factors associated with UHEs, and variation in quality and outcomes in the perfo...

journal_title：Gastroenterology

authors： Huang RJ,Barakat MT,Girotra M,Lee JS,Banerjee S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND & AIMS:Unlike adult antral cells, feline newborn antral cells are unable to contract in response to agonists in the absence of extracellular calcium or in response to exogenous inositol 1,4,5-triphosphate (IP3) after permeabilization. Changes in intracellular pathways that are associated with these differenc...

journal_title：Gastroenterology

authors： Hillemeier AC,Deutsch DE,Bitar KN

更新日期：1997-08-01 00:00:00

abstract：:To study the peripheral effect of somatostatin in dogs a tiny Silastic catheter was implanted in an almost terminal branch of the mesenteric artery, providing blood supply to a jejunal segment of 5-10 cm. In 4 dogs one catheter was implanted, perfusing a small bowel segment about 60 cm below the angle of Treitz; in 3 ...

journal_title：Gastroenterology

authors： Hostein J,Janssens J,Vantrappen G,Peeters TL,Vandeweerd M,Leman G

更新日期：1984-11-01 00:00:00

abstract：:Liver copper concentration was studied in four groups of age-matched patients and in 9 patients with Wilson's disease of comparable age. Neutron activation analysis of hepatic copper concentration revealed markedly elevated hepatic copper levels, comparable with those in Wilson's disease, in 13 of 15 patients (P less ...

journal_title：Gastroenterology

authors： Evans J,Newman S,Sherlock S

更新日期：1978-11-01 00:00:00

abstract：:Interleukin 2, a soluble product of activated T lymphocytes, is of central importance in the development of an appropriate T-cell immune response. Defects in the production of or response to this lymphokine have been described in a variety of immune deficiency and autoimmune states, thus suggesting a role in the patho...

journal_title：Gastroenterology

authors： Fiocchi C,Hilfiker ML,Youngman KR,Doerder NC,Finke JH

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND & AIMS:Previous research has yielded conflicting data as to whether the natural history of inflammatory bowel disease follows a seasonal pattern. The purpose of this study was to determine whether relapse of inflammatory bowel disease follows a seasonal pattern either across a cohort of patients or within in...

journal_title：Gastroenterology

authors： Lewis JD,Aberra FN,Lichtenstein GR,Bilker WB,Brensinger C,Strom BL

更新日期：2004-03-01 00:00:00