The effect of cismethrin on the rat dorsal root potentials.

Abstract:

:Dorsal root potentials were recorded from urethane-anaesthetised rats. Bicuculline, a recognised GABA antagonist, reduced the amplitude of the potential to 67% of control. Cismethrin, a synthetic pyrethroid insecticide, enhanced the potential to 142% of control values. The convulsions associated with cismethrin poisoning therefore are not produced by an antagonism of GABA-mediated inhibitory transmission.

journal_name

Eur J Pharmacol

authors

Smith PR

doi

10.1016/0014-2999(80)90304-0

subject

Has Abstract

pub_date

1980-08-22 00:00:00

pages

125-8

issue

1

eissn

0014-2999

issn

1879-0712

pii

0014-2999(80)90304-0

journal_volume

66

pub_type

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