Vagotomy and pyloroplasty in the treatment of duodenal ulceration. Long-term results.

Abstract:

:In the years 1960 through 1966, vagotomy and pyloroplasty was performed for duodenal ulceration in 182 patients. Elective operation was performed in 84% of cases, and intractability of symptoms was the major indication. For emergency operations, bleeding was the main indication. Eight of 182 patients died in the postoperative period (operative mortality 4.4%--3.3% elective, 10.3% emergency). Follow-up of 1 to 17 years has been obtained in 154 of 182 patients (96% of these from 5 to 17 years). Ulcer recurred in 12.3% of cases (13.6% elective, 4.5% emergency); the average time to recurrence was 4.8 years. Fully 37% of recurrent ulcers were documented 6 years or more postoperatively. Morbidity was significant; diarrhea and "dumping" were the most noteworthy sequelae, and these occurred in 16.2% and 7.8% of cases, respectively. "Postgastrectomy sequelae" occurred in 61 of 154 patients. It is concluded from this study that vagotomy and phyloroplasty, as currently practiced and used in the elective surgical treatment of chronic duodenal ulceration, does not sufficiently protect against recurrence of ulcer.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Pemberton JH,van Heerden JA

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

14-8

issue

1

eissn

0025-6196

issn

1942-5546

journal_volume

55

pub_type

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