Abstract:
:Thirty-one Kanagawa-positive and -negative Vibrio parahaemolyticus isolates from patient stools and seafood were examined for plasmid deoxyribonucleic acid content, culture characteristics, and indices of pathogenicity. No significant correlation was found between plasmid deoxyribonucleic acid contents and indices of pathogenicity for the strains tested.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Twedt RM,Brown DF,Zink DLdoi
10.1128/IAI.33.1.322-325.1981subject
Has Abstractpub_date
1981-07-01 00:00:00pages
322-5issue
1eissn
0019-9567issn
1098-5522journal_volume
33pub_type
杂志文章abstract::Streptococcus pneumoniae sortase A (SrtA) is a transpeptidase that is highly conserved among pneumococcal strains, whose involvement in adhesion/colonization has been reported. We found that intraperitoneal immunization with recombinant SrtA conferred to mice protection against S. pneumoniae intraperitoneal challenge ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01516-08
更新日期:2009-07-01 00:00:00
abstract::The genes of the lic1 operon (lic1A to lic1D) are responsible for incorporation of phosphocholine (PCho) into the lipopolysaccharide (LPS) of Haemophilus influenzae. PCho plays a multifaceted role in the commensal and pathogenic lifestyles of a range of mucosal pathogens, including H. influenzae. Structural studies of...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00748-07
更新日期:2008-02-01 00:00:00
abstract::Immunoglobulin G (IgG)- and IgM-specific antibody titers against Salmonella typhi Ty2 porins have been measured in 30 paired typhoid sera by enzyme-linked immunosorbent assay. These studies have found that IgG serum titers of acute and convalescent sera were 625 and 5,000 times higher, respectively than the control se...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.52.1.209-212.1986
更新日期:1986-04-01 00:00:00
abstract::The intracellular pathogen Listeria monocytogenes replicates mainly in resting macrophages and hepatocytes residing in infected tissues. Both innate and acquired resistance strongly depend on activation of listericidal capacities of macrophages by gamma interferon (IFN-gamma) produced by natural killer cells and T lym...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.63.8.3187-3195.1995
更新日期:1995-08-01 00:00:00
abstract::Cell surface protein SSP-5 in the oral bacterium Streptococcus gordonii M5 binds human salivary agglutinin in a Ca(2+)-dependent reaction (D.R. Demuth, E.E. Golub, and D. Malamud, J. Biol. Chem. 265:7120-7126, 1990). The region of the gene encoding an N-terminal segment of a related polypeptide (SspA) in S. gordonii D...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.61.8.3199-3208.1993
更新日期:1993-08-01 00:00:00
abstract::Challenges with the production and suboptimal immunogenicity of malaria vaccine candidates have slowed the development of a Plasmodium falciparum multiantigen vaccine. Attempting to resolve these issues, we focused on the use of highly immunogenic merozoite surface protein 8 (MSP8) as a vaccine carrier protein. Previo...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00486-17
更新日期:2017-12-19 00:00:00
abstract::Despite the high prevalence of cutaneous infections, little is known about the role of host immune responsiveness during Staphylococcus aureus dermatitis. We have recently described a murine model of infectious dermatitis induced by superantigen-producing S. aureus. To assess the role of neutrophils in staphylococcal ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.68.11.6162-6167.2000
更新日期:2000-11-01 00:00:00
abstract::Exogenous ammonium ions (NH(4) (+)) and amine compounds had a profound influence on the antibacterial activity of the myeloperoxidase-hydrogen peroxide-chloride system against Escherichia coli. The rate of killing increased in the presence of NH(4) (+) and certain guanidino compounds and decreased in the presence of a...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.25.1.110-116.1979
更新日期:1979-07-01 00:00:00
abstract::Localized juvenile periodontitis (LJP) runs in families, and a predisposition to develop disease appears to be inherited in an autosomal dominant fashion. Patients with LJP have elevated levels of serum immunoglobulin G2 (IgG2), and this is most striking in black LJP patients. We hypothesized that the markedly elevate...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.64.6.2004-2009.1996
更新日期:1996-06-01 00:00:00
abstract::The immunodominant proteins and glycoproteins of Borrelia burgdorferi were analyzed by one-dimensional (1D) and 2D gel electrophoresis. More than 100 polypeptide species could be detected on silver-stained 2D gels. Separation of sonic extracts of the organism by differential centrifugation (100,000 X g) revealed sever...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.57.11.3637-3645.1989
更新日期:1989-11-01 00:00:00
abstract::We purified three proline-rich antimicrobial peptides from elastase-treated extracts of sheep and goat leukocytes and subjected two of them, OaBac5alpha and ChBac5, to detailed analysis. OaBac5alpha and ChBac5 were homologous to each other and to bovine Bac5. Both exhibited potent, broad-spectrum antimicrobial activit...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.67.8.4106-4111.1999
更新日期:1999-08-01 00:00:00
abstract::Immunoprecipitation of radiolabeled antigens with bovine antisera indicated that many Babesia bigemina and Babesia bovis merozoite proteins contain isolate-common epitopes, while at least 16 B. bigemina and 8 B. bovis proteins contain species-cross-reactive epitopes. One immunogenic, isolate-common, and species-specif...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.56.6.1658-1660.1988
更新日期:1988-06-01 00:00:00
abstract::Malaria elimination efforts would benefit from vaccines that block transmission of Plasmodium falciparum gametocytes from humans to mosquitoes. A clear understanding of gametocyte-specific antibody responses in exposed populations could help determine whether transmission-blocking vaccines (TBV) would be boosted by na...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00644-15
更新日期:2015-11-01 00:00:00
abstract::Human immunodeficiency virus (HIV)-infected individuals are predisposed to recurrent oral candidiasis, and, although it has been assumed that this is because of deficient mucosal immune responses, this has not been properly established. The present study aimed to compare the concentrations and secretion rates of immun...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.62.3.892-896.1994
更新日期:1994-03-01 00:00:00
abstract::After interaction with tracheal epithelial cells, Bordetella pertussis induces the secretion of interleukin-6. This secretion is dependent on the expression of adenylate cyclase-hemolysin by the bacterium but not on the expression of other characterized bacterial toxins or adhesins. This finding confirms the important...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.72.9.5530-5533.2004
更新日期:2004-09-01 00:00:00
abstract::A major problem in the study of chlamydial genital infections in animal models has been the use of varied doses of chlamydiae for infection in different laboratories. It is clearly desirable to use a dose which approximates that of natural sexual infection, but that dose to date has not been determined because of the ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.71.11.6148-6154.2003
更新日期:2003-11-01 00:00:00
abstract::Increased resistance to infection with Brucella abortus 2308 resulted when recombinant murine gamma interferon (rMuIFN-gamma) was given to mice both before and during infection but not when given only before infection. Mice given rMuIFN-gamma had enhanced peritoneal and splenic macrophage bactericidal activity against...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.60.10.4407-4409.1992
更新日期:1992-10-01 00:00:00
abstract::Newly recognized Fic family virulence proteins may be important in many bacterial pathogens. To relate cellular mechanisms to pathogenesis and immune protection, we studied the cytotoxicity of the Histophilus somni immunoglobulin-binding protein A (IbpA) direct repeat 2 Fic domain (DR2/Fic) for natural host target cel...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01277-09
更新日期:2010-05-01 00:00:00
abstract::Immune and pathologic responses were measured for 20 weeks after infection of mice with Brucella abortus 19, RB51, or 2308. Live bacteria and bacterial antigens of 19 and RB51 persisted in spleens for 10 and 4 weeks after infection, respectively, whereas 2308 bacteria and bacterial antigens persisted for at least 20 w...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.62.8.3206-3212.1994
更新日期:1994-08-01 00:00:00
abstract::Thirteen Habs-serotype strains could be classified into 11 groups depending on the characteristic patterns of 2-amino sugar composition; strains of serotypes 2, 5, and 7 had the same pattern, and each other serotype strain had its own distinctive pattern. In our classification, fucosamine and quinovosamine were of imp...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.15.3.692-697.1977
更新日期:1977-03-01 00:00:00
abstract::It has been proposed that a multivalent malaria vaccine is necessary to mimic the naturally acquired resistance to this disease observed in humans. A major experimental challenge is to identify the optimal components to be used in such a multivalent vaccine. Expression library immunization (ELI) is a method for screen...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.71.8.4506-4515.2003
更新日期:2003-08-01 00:00:00
abstract::The present study was performed to determine whether Histoplasma capsulatum (yeast phase) is able to activate the alternative complement pathway. H. capsulatum yeasts were shown to consume C3 in C4-deficient guinea pig serum. Immunoelectrophoretic conversion of alternative pathway component factor B confirmed that C3 ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.30.1.147-149.1980
更新日期:1980-10-01 00:00:00
abstract::Escherichia coli strains expressing the K1 capsule are a major cause of sepsis and meningitis in human neonates. The development of these diseases is dependent on the expression of a range of virulence factors, many of which remain uncharacterized. Here, we show that all but 1 of 34 E. coli K1 neonatal isolates carrie...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00716-15
更新日期:2015-09-01 00:00:00
abstract::Ehrlichia chaffeensis, a tick-transmitted obligate intracellular rickettsial agent, causes human monocytic ehrlichiosis. In recent reports, we described substantial advances in developing random and targeted gene disruption methods to investigate the functions of E. chaffeensis genes. We reported earlier that the Hima...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00316-20
更新日期:2020-09-18 00:00:00
abstract::An experimental model of "chronic" diphtheria intoxication in the guinea pig was developed. Adult guinea pigs, subjected to a regimen of multiple sublethal doses of purified diphtheria toxin (total of 1.4 minimum lethal doses divided equally in four daily doses), developed a toxemia which terminated in death between 6...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.4.556-560.1973
更新日期:1973-04-01 00:00:00
abstract::In an earlier report, we had described the isolation and characterization of autolysis-defective mutants of Staphylococcus aureus (N. Mani, P. Tobin, and R.K. Jayaswal, J. Bacteriol. 175:1493-1499, 1993). In the study reported here, an autolysis-defective mutant showed attenuated virulence in a rat model of experiment...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.62.4.1406-1409.1994
更新日期:1994-04-01 00:00:00
abstract::Anti-rabbit alveolar macrophage goat serum (AMS), adsorbed of hemolysins and hemagglutinins, exhibited complement-dependent cytotoxicity for the following rabbit target cells: alveolar macrophages, thymocytes, and kidney (RK-13) cells. The intravenous injection of AMS, sufficient to reduce markedly the dermal tubercul...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.2.6.810-814.1970
更新日期:1970-12-01 00:00:00
abstract::Cells in the Brucella spp. are intracellular pathogens that survive and replicate within host monocytes. Brucella maintains persistent infections in animals despite the production of high levels of anti-Brucella-specific antibodies. To determine the effect of antibody opsonization on the ability of Brucella to establi...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.73.6.3702-3713.2005
更新日期:2005-06-01 00:00:00
abstract::Three groups of cattle, each group comprising six animals, were inoculated intravenously with populations of bloodstream forms of Trypanosoma vivax. The first group received T. vivax clone ILDat 1.3 derived from an isolate from Nigeria, while the other two received T. vivax stocks IL 1875 or IL 2133 isolated from Coas...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.54.2.444-447.1986
更新日期:1986-11-01 00:00:00
abstract::Brucellosis is a bacterial disease of animals and humans. Brucella abortus barely activates the innate immune system at the onset of infection, and this bacterium is resistant to the microbicidal action of complement. Since complement stands as the first line of defense during bacterial invasions, we explored the role...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00567-18
更新日期:2018-09-21 00:00:00