Horizontal cell processes in teleost retina.

abstract：:Adult neurogenesis is influenced by blood-borne factors. In this context, greater or lesser vascular permeability along neurogenic niches would expose differentially neural stem cells (NSCs), transit amplifying cells (TACs), and neuroblasts to such factors. Here we evaluate endothelial cell morphology and vascular per...

journal_title：Journal of neuroscience research

authors： Colín-Castelán D,Ramírez-Santos J,Gutiérrez-Ospina G

更新日期：2016-02-01 00:00:00

abstract：:Post-translational modification of neural cell adhesion molecule (NCAM) with alpha2,8-linked polysialic acid, which regulates homophilic adhesion and/or signal transduction events, is crucial to synaptic plasticity in the developing and adult brain. Evidence from in vitro models has implicated polysialylation in the r...

journal_title：Journal of neuroscience research

authors： Gallagher HC,Odumeru OA,Regan CM

更新日期：2000-09-15 00:00:00

abstract：:Despite consistent observations of sex differences in depression and related emotional disorders, we do not yet know how these sex differences modulate the effects of genetic polymorphisms implicated in risk for these disorders. This Mini-Review focuses on genetic polymorphisms of the serotonergic system to illustrate...

journal_title：Journal of neuroscience research

authors： Perry LM,Goldstein-Piekarski AN,Williams LM

更新日期：2017-01-02 00:00:00

abstract：:Apolipoprotein E (ApoE) is the major brain lipoprotein and plays an important role in lipid transport. ApoE-deficient mice whose apoE gene has been knocked out have distinct cognitive and neurochemical deficits, and their recovery from brain injury is impaired. In the present study we examined the possibility that the...

journal_title：Journal of neuroscience research

authors： Lomnitski L,Oron L,Sklan D,Michaelson DM

更新日期：1999-11-15 00:00:00

abstract：:Heat shock protein 60 (HSP60) and HSP10 are mitochondrial chaperonin proteins and are responsible for the folding of newly imported proteins and 13 polypeptides encoded by mitochondrial DNA. The expressions of HSP60 and HSP10 are regulated simultaneously because these genes are localized head to head on chromosome, se...

journal_title：Journal of neuroscience research

authors： Kim SW,Lee JK

更新日期：2007-05-01 00:00:00

abstract：:The osteoinductive capacity of biological noncellular material has been widely recognized. Studies using bone morphogenetic proteins and acellular bone matrix demonstrate that host mesenchymal cells can be readily transformed into osteoprogenitor cells. The current study sought to determine whether another biological ...

journal_title：Journal of neuroscience research

authors： Carpenter EM,Llamas C,Buck BE,Malinin TI

更新日期：2015-03-01 00:00:00

abstract：:In the following review, we address difficulties that have arisen when attempting to convert the myelin multilayers into vesicles. The emphasis is on CNS myelin of adult mammals although both central nervous system (CNS) and peripheral nervous system (PNS) myelin are considered. The ability to prepare vesicle of myeli...

journal_title：Journal of neuroscience research

authors： Sedzik J,Blaurock AE

更新日期：1995-06-01 00:00:00

abstract：:Neural precursor cells (NPCs) critically regulate brain morphogenesis and recent studies have revealed an unexpectedly high frequency of NPC chromosomal abnormalities and apoptosis in the developing brain. We have shown previously that the apoptotic response of NPCs to genotoxic agents is dependent on p53 and caspase-...

journal_title：Journal of neuroscience research

authors： D'Sa C,Klocke BJ,Cecconi F,Lindsten T,Thompson CB,Korsmeyer SJ,Flavell RA,Roth KA

更新日期：2003-11-01 00:00:00

abstract：:Muscarinic cholinergic receptors of the M5 subtype are expressed by dopamine-containing neurons of the ventral tegmentum. These M5 receptors modulate the activity of midbrain dopaminergic neurons, which play an important role in mediating reinforcing properties of abused psychostimulants like cocaine. The potential ro...

journal_title：Journal of neuroscience research

authors： Fink-Jensen A,Fedorova I,Wörtwein G,Woldbye DP,Rasmussen T,Thomsen M,Bolwig TG,Knitowski KM,McKinzie DL,Yamada M,Wess J,Basile A

更新日期：2003-10-01 00:00:00

abstract：:The increase in myelin basic protein (MBP) synthesis observed in brain aggregate cultures supplemented with macrophages is reflected in elevated supernatant protein levels of the key promoters of oligodendrocyte proliferation, fibroblast growth factor-2 (FGF-2) and platelet-derived growth factor-AA (PDGF-AA), during t...

journal_title：Journal of neuroscience research

authors： Diemel LT,Jackson SJ,Cuzner ML

更新日期：2003-12-15 00:00:00

abstract：:Antiglycolipid IgM antibodies are known to induce formation of "wide spaced" or "expanded" myelin, a distinctive form of dysmyelination characterized by a repeat period approximately two or three times normal, which is seen also in diseases, including multiple sclerosis. To determine whether an antibody directed again...

journal_title：Journal of neuroscience research

authors： Rosenbluth J,Schiff R

更新日期：2009-03-01 00:00:00

abstract：:Acute intoxication with large ammonia doses leads to activation of NMDA receptors in the brain, resulting in oxidative stress and disturbance of mitochondrial function. Altered mitochondrial function is a crucial step in some mechanisms of cellular apoptosis. This study assesses whether ammonia intoxication in vivo le...

journal_title：Journal of neuroscience research

authors： Kosenko E,Kaminsky Y,Solomadin I,Marov N,Venediktova N,Felipo V,Montoliu C

更新日期：2007-08-15 00:00:00

abstract：:Brain edema accounts for significant morbidity and mortality in many neurologic conditions such as head trauma, stroke, meningitis, and brain tumor. The water channel aquaporin-4 (AQP4) has been found to be an important determinant of brain water accumulation and clearance of excess brain water. We report the developm...

journal_title：Journal of neuroscience research

authors： Thiagarajah JR,Papadopoulos MC,Verkman AS

更新日期：2005-04-15 00:00:00

abstract：:Neuroepithelial b2T cells were derived from the hindbrain and the spinal cord of mouse transgenic embryos, which expressed SV40 T antigen under the control of a Hoxb2 enhancer. Strikingly, b2T cell lines of either origin exhibit a very similar gene expression pattern, including markers of the hindbrain and the spinal ...

journal_title：Journal of neuroscience research

authors： Nardelli J,Catala M,Charnay P

更新日期：2003-09-15 00:00:00

abstract：:The galactolipids galactocerebroside and sulfatide have been implicated in oligodendrocyte (OL) development and myelin formation. Much of the early evidence for myelin galactolipid function has been derived from antibody and chemical perturbation of OLs in vitro. To determine the role of these lipids in vivo, we previ...

journal_title：Journal of neuroscience research

authors： Shroff SM,Pomicter AD,Chow WN,Fox MA,Colello RJ,Henderson SC,Dupree JL

更新日期：2009-11-15 00:00:00

abstract：:The amino acid glutamate plays a key role in brain function. One of the major roles of glutamate is to mediate fast excitatory neurotransmission via activation of ionotropic glutamate receptors (iGluRs). More recently, however, it has become clear that glutamate also serves a regulatory function through activation of ...

journal_title：Journal of neuroscience research

authors： Winder DG,Conn PJ

更新日期：1996-10-15 00:00:00

abstract：:Neurogenesis of heterotopic gray matter in the brain of the microcephalic mouse prenatally exposed to X-rays at embryonic day 13 (E13) was studied immunohistochemically. Bromodeoxyuridine (BrdU) as a marker to label the migrating position of neuroblasts generated at various embryonic stages showed that no "inside-out"...

journal_title：Journal of neuroscience research

authors： Sun XZ,Takahashi S,Fukui Y,Hisano S,Kubota Y,Sato H,Inouye M

更新日期：2001-12-15 00:00:00

abstract：:The effects of cations on the spontaneous and potassium-stimulated taurine release from mouse cerebral cortex slices were assessed with an emphasis on the as yet unestablished calcium dependence of the stimulated release. Spontaneous and stimulated GABA release was analyzed for comparison. A depolarizing concentration...

journal_title：Journal of neuroscience research

authors： Oja SS,Kontro P

更新日期：1987-01-01 00:00:00

abstract：:The neural cell adhesion molecule (NCAM) plays a key role in neural development, regeneration, and synaptic plasticity. The crystal structure of a fragment of NCAM comprising the three N-terminal immunoglobulin (Ig)-like modules indicates that the first and second Ig modules bind to each other, thereby presumably medi...

journal_title：Journal of neuroscience research

authors： Køhler LB,Soroka V,Korshunova I,Berezin V,Bock E

更新日期：2010-08-01 00:00:00

abstract：:Previously we reported results of an incubation experiment with neurofilaments that supported the existence of a mu-type of Ca2+-activated neutral protease in the rat peripheral nerve; it was active with microM order Ca2+ (mu-CANP). This time, we partially purified the mu-CANP from a crude CANP fraction of rat periphe...

journal_title：Journal of neuroscience research

authors： Kamakura K,Ishiura S,Sugita H

更新日期：1986-01-01 00:00:00

abstract：:Double immunofluorescence studies using antibodies against NF-L and peripherin revealed three distinct subpopulations of neurons in rat dorsal root ganglia (DRG). In the adult rat, 46% of the DRG neurons were small and peripherin-positive (NF-L-negative), and 48% were large and NF-L-positive (peripherin-negative). Abo...

journal_title：Journal of neuroscience research

authors： Goldstein ME,House SB,Gainer H

更新日期：1991-09-01 00:00:00

abstract：:A previous study demonstrated the release of newly loaded radiolabelled taurine (Tau) from cultured rabbit Müller glia not only following typical cell volume-increasing treatments with high (65 mM) potassium ions or hypotonic media, but also with ammonium chloride (further referred to as ammonia), in a dose-dependent ...

journal_title：Journal of neuroscience research

authors： Faff L,Reichenbach A,Albrecht J

更新日期：1996-10-15 00:00:00

abstract：:Little is known about the structural neural substrates that may contribute to sex differences in risk-taking propensity (RTP). A close association between risk-seeking behavior and the emotional-regulation network led us to hypothesize that the sex differences in RTP would be associated with sex differences in brain m...

journal_title：Journal of neuroscience research

authors： Bajaj S,Killgore WDS

更新日期：2020-02-01 00:00:00

abstract：:A-type K+ channels (IA channels) contribute to learning and memory mechanisms by regulating neuronal excitabilities in the CNS, and their expression level is targeted by Ca2+ influx via synaptic NMDA receptors (NMDARs) during long-term potentiation (LTP). However, it is not clear how local synaptic Ca2+ changes induce...

journal_title：Journal of neuroscience research

authors： Yang YS,Jeon SC,Kang MS,Kim SH,Eun SY,Jin SH,Jung SC

更新日期：2017-12-01 00:00:00

abstract：:The chemokines, macrophage inflammatory protein-1 (MIP-1) and its subunit MIP-1 beta, induce an intense fever in the rat when they are injected directly into the anterior hypothalamic, pre-optic area (AH/POA), a region containing thermosensitive neurons. The purpose of this study was to compare the central action on b...

journal_title：Journal of neuroscience research

authors： Myers RD,Lopez-Valpuesta FJ,Miñano FJ,Wooten MH,Barwick VS,Wolpe SD

更新日期：1994-09-01 00:00:00

abstract：:Fibroblast growth factors (FGFs) are known to act on glial cells in vitro. At the present time, their involvement in the remyelinating process of the adult central nervous system (CNS) is still unknown. In the present study, using immunohistochemistry (IHC), we investigated the evolution in time and space of acidic FG...

journal_title：Journal of neuroscience research

authors： Tourbah A,Baron-Van Evercooren A,Oliver L,Raulais D,Jeanny JC,Gumpel M

更新日期：1992-09-01 00:00:00

abstract：:Lithium, the most prevalent treatment for manic-depressive illness, might have a neuroprotective effect after brain injury. In culture, lithium can exert neurotoxic effects associated with reduction in polyamine synthesis but neuroprotective effects as cultured neurons mature. Cumulative evidence suggests that lithium...

journal_title：Journal of neuroscience research

authors： Gilad GM,Gilad VH

更新日期：2007-02-15 00:00:00

abstract：:Previously, we have demonstrated a novel interaction between Galpha(o) protein and Purkinje cell protein-2 (Pcp2, also known as L7) in vitro and in transfected cells (Luo and Denker [1999] J. Biol. Chem. 274:10685-10688). Pcp2 is uniquely expressed in cerebellar Purkinje cells and in retinal bipolar neurons, and it ma...

journal_title：Journal of neuroscience research

authors： Redd KJ,Oberdick J,McCoy J,Denker BM,Luo Y

更新日期：2002-12-01 00:00:00

abstract：:The neural cell adhesion molecule L1 is a multidomain protein that plays important roles in cell adhesion, migration, and neurite outgrowth. It can interact with itself by a self-binding, i.e., homophilic adhesion mechanism (Kadmon et al.: J Cell Biol 110: 193-208, 1990a). To determine the domains of L1 involved in ho...

journal_title：Journal of neuroscience research

authors： Holm J,Appel F,Schachner M

更新日期：1995-09-01 00:00:00

abstract：:It is suggested that masticatory dysfunction affects the central nervous system; however, the underlying mechanism remains unknown. Brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, are known to play important roles in memory and learning. In this study, we examined the effects of mastication on memory,...

journal_title：Journal of neuroscience research

authors： Okihara H,Ito J,Kokai S,Ishida T,Hiranuma M,Kato C,Yabushita T,Ishida K,Ono T,Michikawa M

更新日期：2014-08-01 00:00:00