Abstract:
:Continuous ethinyl estradiol treatment following ovariectomy at day 38 of BALB/cfC3H mice treated neonatally with estradiol resulted in a more organized vaginal epithelium than that seen in the absence of postnatal estrogen, 30 days after treatment was initiated. Although the epithelium became increasingly disorganized in all neonatally estrogenized groups with age, the later estrogen treatment reduced the incidence and severity of vaginal epithelial lesions and the incidence of vaginal concretions. Uterine epithelial metaplasia was accelerated by the later estrogen treatment.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Wong LM,Bern HA,Jones LA,Mills KTdoi
10.1016/0304-3835(82)90023-4subject
Has Abstractpub_date
1982-11-01 00:00:00pages
115-23issue
2eissn
0304-3835issn
1872-7980pii
0304-3835(82)90023-4journal_volume
17pub_type
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