Abstract:
:Serum corticosterone levels were determined at intervals after i.p. injection of 1.8 mg cadmium (Cd)/kg body weight. Thymus weight decreased significantly 3 days after injection. The effect of Cd injection on serum corticosterone levels was almost indistinguishable from that of saline injection. Further, Cd-induced thymic atrophy was observed in adrenalectomized mice as well as in sham-operated ones. These results suggest that corticosteroid effect is not essential for the induction of thymic atrophy by Cd.
journal_name
Toxicol Lettjournal_title
Toxicology lettersauthors
Yamada YK,Murakami N,Shimizu F,Kubota Kdoi
10.1016/0378-4274(82)90244-2subject
Has Abstractpub_date
1982-08-01 00:00:00pages
225-9issue
4eissn
0378-4274issn
1879-3169pii
0378-4274(82)90244-2journal_volume
12pub_type
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