Isolation, purification, and antibiotic activity of o-methoxycinnamaldehyde from cinnamon.

Abstract:

:o-Methoxycinnamaldehyde has been isolated and purified from powdered cinnamon. The compound inhibits the growth and toxin production of mycotoxin-producing fungi. The substance completely inhibited the growth of Aspergillus parasiticus and A. flavus at 100 microgram/ml and A. ochraceus and A. versicolor at 200 microgram/ml. It inhibited the production of aflatoxin B1 by over 90% at 6.25 microgram/ml, ochratoxin A at 25 microgram/ml, and sterigmatocystin at 50 microgram/ml. The substance also displayed a strong inhibitory effect on the growth of five dermatophytoses species, e.g., Microsporum canis (minimum inhibitory concentration, 3.12 to 6.25 microgram/ml). However, no antibacterial effect was observed at concentrations as high as 50 microgram/ml.

journal_name

Appl Environ Microbiol

authors

Morozumi S

doi

10.1128/AEM.36.4.577-583.1978

subject

Has Abstract

pub_date

1978-10-01 00:00:00

pages

577-83

issue

4

eissn

0099-2240

issn

1098-5336

journal_volume

36

pub_type

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