Abstract:
:The resonance Raman spectrum of native DNA has been obtained using excitation at 257 nm. In a first part, the spectral lines are assigned to the different nucleotide bases which provide the resonance effect. In a second part, the interactions of DNA with basic peptides (Arginine Methylester, Lysine Methylester, Arginyl-Arginine) are investigated using excitation at 300 nm and 257 nm, which give complementary information about the DNA. Both Arginine Methylester and Arginyl-arginine recognize the A-T base pairs, the first one in the large groove, the second one in the narrow groove of DNA. The DNA-Lysine Methylester interaction is very likely not specific but can take place in the large groove of DNA.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Laigle A,Chinsky L,Turpin PYdoi
10.1093/nar/10.5.1707subject
Has Abstractpub_date
1982-03-11 00:00:00pages
1707-20issue
5eissn
0305-1048issn
1362-4962journal_volume
10pub_type
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