Abstract:
:The fluorescence-activated cell sorter and a rosette-depletion technique were used to separate rat spleen lymphocytes and BCG-activated lymphocytes into subpopulations with and without the antigens defined by W3/13, W3/23 and OX8 monoclonal antibodies. The resultant populations were then tested for natural killer (NK) activity in a quantifiable 6 hr 51Cr release assay. The data establish that rat natural killer cells are heterogeneous with respect to their surface antigen expression and that subpopulations of rat NK cells express the OX8 and W3/13 defined antigens. However, rat NK cells do not express the antigen defined by W3/24 monoclonal antibody.
journal_name
Immunologyjournal_title
Immunologyauthors
Cantrell DA,Robins RA,Brooks CG,Baldwin RWsubject
Has Abstractpub_date
1982-01-01 00:00:00pages
97-103issue
1eissn
0019-2805issn
1365-2567journal_volume
45pub_type
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