Abstract:
:HLA markers (A, B, C, DR loci) were determined for the members of 52 unrelated families with at least one child suffering from congenital adrenal hyperplasia due to 21 hydroxylase deficiency, permitting genotyping. The gene frequencies of the 52 index cases were compared with those obtained from the patients' normal haplotypes and with those of a control reference panel. No significant differences were observed, except a clear decrease in the frequency of HLA-B8 among the haplotypes that carry the gene for congenital adrenal hyperplasia.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Couillin P,Kottler-Missonnier ML,Grisard MC,Hors J,Feingold J,Boué J,Boué Adoi
10.1007/BF00287061subject
Has Abstractpub_date
1980-01-01 00:00:00pages
389-92issue
3eissn
0340-6717issn
1432-1203journal_volume
53pub_type
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