Bone mineral content in idiopathic renal stone disease and in primary hyperparathyroidism.

Abstract:

:Bone mineral content (BMC) was measured with the Norland Cameron apparatus in 120 renal stone formers (RSF) with idiopathic stone disease and in 41 patients with primary hyperparathyroidism. RSF were classified, according to an oral calcium load test, into three groups: no hypercalciuria (HC; 41 cases); absorptive HC (53 cases), and resorptive or renal HC (25 cases). BMC values in RSF as a group were significantly lower than normal (p less than 0.001, Mann-Whitney test) though higher than in hyperparathyroid patients. There was a trend for BMC to decrease from male RSF without HC to patients with renal or resorptive HC. No statistical difference was found between the groups, however, BMC values in absorptive HC were different from normal (p less than 0.001). Why patients with HC are demineralized is unclear since no correlation was found between BMC and basal values of serum phosphate, TRP, calculated TmP/GFR, urinary calcium or hydroxyproline. Nevertheless our results indicate that urolithiasis, and possibly its treatment, is not a benign condition for the skeleton.

journal_name

Eur Urol

journal_title

European urology

authors

Fuss M,Gillet C,Simon J,Vandewalle JC,Schoutens A,Bergmann P

doi

10.1159/000474039

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

32-4

issue

1

eissn

0302-2838

issn

1873-7560

journal_volume

9

pub_type

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