Cerebrospinal fluid lactic acid in diagnosis of meningitis.

Abstract:

:Quantitative lactate determinations were performed on cerebrospinal fluids to assess their value in the rapid diagnosis of bacterial and mycotic meningitis and to evaluate their value in assessing the prognosis in these patients. Cerebrospinal fluid lactate concentrations were elevated in all patients with untreated bacterial or fungal meningitis. Lactate concentrations proved very valuable in following patients with mycotic meningitis and in differentiating aseptic from bacterial meningitis. Elevated cerebrospinal fluid lactate is not specific for meningitis. Lactate is also elevated in situations where there is central nervous system ischemia and necrosis and in patients with brain tumors. Lactate concentration is normal in chronic degenerative brain diseases. Thus, the clinical situation must be taken into account when interpreting the lactate concentrations.

journal_name

J Clin Microbiol

authors

Komorowski RA,Farmer SG,Hanson GA,Hause LL

subject

Has Abstract

pub_date

1978-07-01 00:00:00

pages

89-92

issue

1

eissn

0095-1137

issn

1098-660X

journal_volume

8

pub_type

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