Comparison of expression of the fragile site at Xq27 in T and B lymphocytes.

Abstract:

:We compared the fragile X (fraX) expression in T and B lymphocytes from four hemizygous males with fraX. Blood cultures were stimulated with a T cell mitogen (phytohemagglutinin:PHA) and with a B cell mitogen (pokeweed mitogen:PWM). A significant decrease in fraX expression was observed in cultures stimulated with PWM when compared to PHA-stimulated ones.

journal_name

Hum Genet

journal_title

Human genetics

authors

Marchese CA,Lin MS,Wilson MG

doi

10.1007/BF00273003

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

213

issue

2

eissn

0340-6717

issn

1432-1203

journal_volume

67

pub_type

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