Abstract：
:In the recent years immunological abnormalities, including defective polymorphonuclear neutrophils (PMN) chemotaxis and both quantitative and functional defects in T-lymphocytes, have been reported in atopic dermatitis (AD). To date there is still a controversy regarding the causes of PMN chemotaxis defect and the possible mechanism underlying this abnormality in patients with AD. The aim of this study was to investigate the PMN chemotactic function in 18 children affected with AD and high levels of serum IgE, and in 4 children with Hyper IgE Syndrome (HIES). Our results showed a marked PMN chemotaxis defect (p less than 0.01) in the patients with HIES, while in the subjects with AD PMN cellular chemotaxis was normal and there was no correlation between the results of chemotaxis and serum IgE levels.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Galli E,Rossi P,Fiore L,Perlini R,Celiboni F,Betti P,Businco Lsubject
Has Abstractpub_date
1983-05-01 00:00:00pages
189-94issue
3eissn
0301-0546issn
1578-1267journal_volume
11pub_type
杂志文章abstract：BACKGROUND:Neutrophil-lymphocyte ratio (NLR) is a test used to evaluate the systemic inflammation. There is little knowledge about the neutrophil-lymphocyte ratio in asthmatics. In our study, we aimed to evaluate NLR and to assess its relationship with clinical parameters in children with asthma. METHODS:Four hundred ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.09.005
更新日期：2016-07-01 00:00:00
abstract：:We report a case of nasal candidiasis in an immunocompetent host who denied the use of topical or systemic corticosteroids. The patient was treated with itraconazole 100 mg. with resolution of the symptoms. ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:A case report of occupational hypersensitivity to Spiramycin. Rhinoconjunctivitis and spasmodic cough are reported in a 34 year-old female handling spiramycin powder in a pharmaceutical factory. The symptoms appeared within the first few hours of coming into contact with the drug and continued for several hours after ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：:Proteolytic activity is fundamental to survival, so it is not surprising that all living organisms have proteases, especially seine protease. This enzyme in its numerous isoforms and homologues, constitutes the quintessential offence and defence factors, in the form of surface proteins, secreted molecules, gut digesti...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2016.10.011
更新日期：2017-01-01 00:00:00
abstract：:Thanks to its excellent safety profile, sublingual immunotherapy has served as a basis for launching two important lines of research in current allergology: sublingual immunotherapy with pharmaceutical registry (oral lyophilizates or tablets), and sublingual immunotherapy with food. At present, clinical trials are bei...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(08)75223-6
更新日期：2008-09-01 00:00:00
abstract：:We report immunological studies performed in 19 sera from 4 children with idiopathic pulmonary hemosiderosis (IPH). Circulating C1q binding immune complexes (IC) were found in 3/4 of the patients during the acute phase. One child showed IC in 4 consecutive crises but they disappeared very rapidly (within 36 hours). On...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The relationship between ingestion of cow's milk and lymphocyte transformation in cow's milk allergic children was studied. Fifty-six children were selected. Nineteen of them suffered from cow's milk hypersensitivity (HCM); 22 were allergic to several agents except to cow's milk (HOE) and 15 normal and healthy childre...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Several authors have reported an increase in leukotriene C4 in the premenstrual phase in women with severe premenstrual asthma, indicating that antileukotrienes could be used in treatment. OBJECTIVE:To analyse the role of leukotrienes in premenstrual asthma. METHODS:A questionnaire on respiratory symptoms ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2011.09.007
更新日期：2012-11-01 00:00:00
abstract：:Specific immunotherapy consists of the administration of allergen extracts to patients with allergic disease to achieve clinical tolerance to the causative allergens. Currently, it is the only etiologic treatment for respiratory allergy. A World Health Organization opinion paper published in 1997 defines immunotherapy...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/s0301-0546(04)79300-3
更新日期：2004-05-01 00:00:00
abstract：:In view of the excellent results we had obtained using KETOTIFEN in the treatment of respiratory allergies, we decided to carry out a study of its protective action in cases of allergies of purely alimentary etiology; that is, in patients symptoms only appeared after the ingestion of certain foodstuffs. The subjects o...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：:We report the case of a 42-year-old non-smoking man, who had worked as a carpenter for 6 years and who reported a history of rhinorrhea, paroxysmal sneezing, nasocular pruritus, lacrimation, wheezing and dyspnea attacks while preparing a mixture to seal the junctures between wooden panels. Allergy study consisted of s...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(05)73251-1
更新日期：2005-11-01 00:00:00
abstract：:Perioperative anaphylactic reactions are immediate, hypersensitive reactions that are potentially life-threatening resulting from a sudden release of mediators from mast cells and basophiles, due to either immune (IgE or non-IgE mediated) or non-immune mechanisms. The most frequent causing agents are neuromuscular blo...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2013.07.012
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Food allergy (FA) is an important health problem in western societies; however, there are no data available from developing countries. Studies based on self-reported symptoms range from 1.4 % to 33 %, and it is supposed that FA is more prevalent early in life. To our knowledge in Latin America there has not ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,随机对照试验
doi：10.1016/s0301-0546(08)75863-4
更新日期：2008-11-01 00:00:00
abstract：:Since the first decades of the twentieth century, some authors have believed bacterial respiratory infection to be an important triggering factor in bronchial asthma, drawing attention to an asthmatic response to infection. In this context, already in 1995, we presented a study on nasal secretion cultures and the rela...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/s0301-0546(01)79035-0
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:It is thought that airway inflammation is more common in obese asthmatic patients because inflammation is harder to control and does not respond well to glucocorticoid treatment. OBJECTIVE:This study's aim was to investigate the effect of obesity on airway and systemic inflammation in children with asthma a...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.01.013
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Asthma hospitalization rates in Chilean children have increased in the last 14 years, but little is known about the factors associated with this. OBJECTIVE:Describe clinical characteristics of children hospitalized for asthma exacerbation. METHODS:Observational prospective cohort study in 14 hospitals. Ove...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.aller.2018.02.006
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Children with IgE-mediated cow's milk allergy (IgE-CMA) often tolerate baked milk within a wheat matrix. In our study we evaluated the impact of wheat matrix and of little standardised cooking procedures on tolerance of baked milk. We also tested tolerance versus parmigiano reggiano (PR) and whey-based parti...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2016.03.005
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To report the results of treatment with infliximab in patients with refractory juvenile idiopathic arthritis (JIA). PATIENTS AND METHODS:A prospective study of four children with refractory JIA was carried out. Infliximab (100 mg) was administered in weeks 0, 2 and 6. Subsequently, the drug was administered ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13101338
更新日期：2007-03-01 00:00:00
abstract：:A procedure is described for the cytochemical detection of esterase alpha naphtyl acetate (ANAE) and beta glucuronidase (BG) activity in the circulating lymphocytes of man. The number of BG positive cells (TBG) as evaluated on the smears of Ficoll Urovision purified cells, correlated well with the number of T gamma (E...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1982-03-01 00:00:00
abstract：:This study investigated the specificity and efficacy of immunotherapy with Artemisia vulgaris (Artemisia) extract. We studied 25 patients with a more than two year lasting history of seasonal rhinoconjunctivitis and who had only two clinically important allergies, either to Artemisia and Betula verrucosa (Betula) or t...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-03-01 00:00:00
abstract：:It has recently been published patients suffering from urticaria or anaphylaxia induced by nematodes usually parasitizing fishs or cephalopode, in whom, Anisakis simplex (AK) sensitization prevalence was detected up to 37%. We tried out a prospective study to evaluate the presence of AK specific-IgE in an asthmatic po...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:The inhalation of Parietaria judaica pollen is a common cause of allergic respiratory diseases in the Mediterranean area. The objective of this study was to investigate the safety and clinical efficacy of a chemically modified (depigmented and glutaraldehyde-polymerized) vaccine of Parietaria judaica. METHO...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0301-0546(03)79170-8
更新日期：2003-03-01 00:00:00
abstract：:Atopic dermatitis is a chronic pruritic dermatosis that requires individualized treatment. Recent studies have shown that low-dose oral treatment with cyclosporine A may be useful in more severe forms. We report our experience with two patients who had severe atopic dermatitis. Both had high IgE concentration and sati...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：BACKGROUND:Cytokines, including interleukin-2 (IL-2) and interferon-gamma (IFN-γ), seem to play a role in the pathogenesis of juvenile idiopathic arthritis (JIA). The aim of this study was to investigate the associations of IL-2 and IFN-γ single nucleotide polymorphisms (SNPs) with susceptibility to JIA in an Iranian p...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2015.10.005
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Epidemiological evidence suggests the existence of a direct link between allergic rhinitis (AR) and asthma. Several studies also support the presence of small-airway dysfunction (SAD) in non-asthmatic children with AR. However, it remains unknown whether SAD can predict the progression of AR to asthma. Our o...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2017.09.025
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:Chronic granulomatous disease (CGD) is an uncommon primary immune deficiency (affecting 1/200,000 newborn infants) caused by a defect in phagocyte production of oxygen metabolites, and resulting in bacterial infections produced by catalase-positive microorganisms and fungal diseases that occasionally may p...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13106774
更新日期：2007-05-01 00:00:00
abstract：:The occurrence of allergic diseases depends on genetic and environmental factors. Genetic factors determine individual risk and these persons should undergo early detection. However, the methods currently available (mainly clinical history and IgE in umbilical cord blood) have poor predictive value so their use in the...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-05-01 00:00:00
abstract：:Lumry described 6 patients who presented hypertrophic rhinosinusitis, positive nasal eosinophilia and intolerance to nonsteroidal antiinflammatory drugs, manifested exclusively with naso-ocular symptomatology. We present three patients with clinical manifestations of chronic rhinitis who had noticed before their first...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：BACKGROUND:Although it has been hypothesized that infections may play a preventive role in allergic diseases, the role of Helicobacter pylori (H. pylori) is not clear. In this study we aimed to determine the association between H. pylori infection and allergic inflammation. METHODS:H. pylori infection was assessed in ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13120393
更新日期：2008-03-01 00:00:00
abstract：:The mechanisms of action of prophylactic antiallergic drugs, especially disodium cromoglycate (DSCG), have been reviewed. Some evidence is presented that suggests that DSCG acts not only as an inhibitor of mediator release from mast cells, but also by inhibiting the effects of mediators on bronchial and intestinal smo...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：
更新日期：1981-11-01 00:00:00
