Abstract：
:Capillary diameters in sartorius muscle of frogs were measured in vivo by means of a new computer video method, based on the passage of red blood cells (RBCs) through the capillary (C. Ellis, R. Sanfranyos, and A. Groom (1983), Microvasc. Res. 26, 139-150). The distribution of capillary diameters from 21 frogs was represented by a histogram with a mean +/- SD of 16.7 +/- 4.4 microns (N = 83). The measured dimensions (mean +/- SD) of frog RBCs, which have a flattened ellipsoidal shape, were: major axis = 24.1 +/- 2.6 microns (N = 149); minor axis = 16.5 +/- 1.5 microns (N = 158); thickness at center = 5.4 +/- 0.8 microns (N = 32). Frog RBCs travel through capillaries with their major axes predominantly parallel to the direction of flow; therefore, RBCs pass through capillaries without deformation provided that the diameter of the capillary is larger than the minor axis of the cell. By standardizing the measured values of capillary diameter in terms of mean minor dimension of the RBCs (ratio of means for frog being 1.0, approx), we were able to compare the diameter distribution in an amphibian with that in a mammal (rat). If RBC size alone mattered, both standardized distributions should superimpose; however, that for frog was shifted to the right of that for rat, indicating that frog RBCs are less deformable than RBCs of rat. This highlights the necessity, in the microcirculation, for matching capillary diameter to both size and deformability of the red cell.
journal_name
Microvasc Resjournal_title
Microvascular researchauthors
Safranyos RG,Ellis CG,Tyml K,Groom ACdoi
10.1016/0026-2862(83)90066-3subject
Has Abstractpub_date
1983-09-01 00:00:00pages
151-6issue
2eissn
0026-2862issn
1095-9319pii
0026-2862(83)90066-3journal_volume
26pub_type
杂志文章abstract：:Normal brain parenchyma has a highly complex microvascular structure that undergoes re-modelling in the presence of a tumor. A detailed understanding of the clinical and pathological aspects of neo-angiogenesis in malignant human brain tumors is essential in order to ensure the successful clinical application of anti-...
journal_title：Microvascular research
pub_type： 杂志文章,评审
doi：10.1016/j.mvr.2010.09.005
更新日期：2010-12-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1998.2086
更新日期：1998-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2004.08.001
更新日期：2004-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.1995.1064
更新日期：1995-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2005.03.001
更新日期：2005-05-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章,评审
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更新日期：2021-03-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2014.12.002
更新日期：2015-03-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(85)90051-2
更新日期：1985-09-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2015.01.007
更新日期：2015-03-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.2000.2279
更新日期：2000-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2016.01.005
更新日期：2016-05-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章,评审
doi：10.1016/j.mvr.2020.104027
更新日期：2020-09-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2011.04.004
更新日期：2011-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2005.10.003
更新日期：2005-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2012.10.005
更新日期：2013-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2010.02.005
更新日期：2010-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2014.02.006
更新日期：2014-05-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2018.11.002
更新日期：2019-03-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2018.09.001
更新日期：2019-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：
更新日期：2013-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1006/mvre.2001.2381
更新日期：2002-03-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(88)90058-1
更新日期：1988-03-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
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更新日期：2006-11-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2014.05.008
更新日期：2014-07-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章,评审
doi：10.1016/j.mvr.2007.05.005
更新日期：2007-09-01 00:00:00
abstract：:Polyphenolic compounds (anthocyanins, flavonoid glycosides) in berries prevent the initiation, promotion, and progression of carcinogenesis in rat's digestive tract and esophagus, in part, via anti-inflammatory pathways. Angiogenesis has been implicated in the pathogenesis of chronic inflammation and tumorigenesis. In...
journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2014.10.008
更新日期：2015-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2015.02.004
更新日期：2015-05-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(90)90061-u
更新日期：1990-01-01 00:00:00
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journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/j.mvr.2018.10.003
更新日期：2019-05-01 00:00:00
abstract：:Oxygen pressure histograms were determined with the multiwire surface electrode from the gastrocnemius muscle in patients with arterial occlusive disease and compared with those of healthy volunteers. Seven out of 22 patients had normally distributed histograms like volunteers, but the mean PO2 values were lower than ...
journal_title：Microvascular research
pub_type： 杂志文章
doi：10.1016/0026-2862(85)90024-x
更新日期：1985-05-01 00:00:00
