Abstract:
:Autoradiographic studies showed selective accumulation of [3H]-glycine, [3H]-GABA, and the GABA agonist [3H]-muscimol by neurons of the mudpuppy retina. [3H]-Glycine was taken up by bipolar cells, amacrine cells, and displaced amacrine or ganglion cells. Both [3H]-GABA and [3H]-muscimol were also accumulated by bipolar cells, amacrine cells and ganglion layer cells. However, the [3H]-GABA uptake pattern differed from that of [3H]-muscimol in showing labeling of horizontal cells, an increased percentage of cells in the ganglion cell layer, and a band in the most proximal portion of the inner plexiform layer. Variations in grain density suggested the presence of multiple subpopulations of [3H]-glycine- and [3H]-GABA-labeled amacrine cells. The labeled cells may play a role in inhibitory pathways in the inner retina.
journal_name
Exp Eye Resjournal_title
Experimental eye researchauthors
Pourch RG,Goebel DJ,McReynolds JSdoi
10.1016/0014-4835(84)90116-7subject
Has Abstractpub_date
1984-07-01 00:00:00pages
69-81issue
1eissn
0014-4835issn
1096-0007journal_volume
39pub_type
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journal_title:Experimental eye research
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更新日期:1990-01-01 00:00:00
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journal_title:Experimental eye research
pub_type: 杂志文章
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更新日期:1983-12-01 00:00:00
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journal_title:Experimental eye research
pub_type: 杂志文章
doi:10.1006/exer.1996.0177
更新日期:1997-01-01 00:00:00
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更新日期:1988-08-01 00:00:00
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