Abstract:
:To study the effects of inhaled NiO particles on alveolar macrophages and the humoral immune system, male Wistar rats were continuously exposed to NiO aerosols for 4 weeks and 4 months, respectively. Fractions of alveolar macrophages, granulocytes, and lymphocytes in lung lavages, number of polynucleated macrophages, size of macrophages, and phagocytic activity were determined. To test the effects on the humoral immune response sheep erythrocytes were injected, and the antiserum titer in blood and the portion of antibody forming cells in spleen were measured. Significant alterations were found in both systems at 100 and 200 micrograms Ni/m3 after 4 weeks of exposure and at 25 and 150 micrograms Ni/m3 after 4 months of exposure, respectively. The results demonstrate the usefulness of investigations on the humoral immune system and alveolar macrophages as sensitive parameters in detecting effects of NiO inhalation.
journal_name
Ecotoxicol Environ Safjournal_title
Ecotoxicology and environmental safetyauthors
Spiegelberg T,Kördel W,Hochrainer Ddoi
10.1016/0147-6513(84)90011-3subject
Has Abstractpub_date
1984-12-01 00:00:00pages
516-25issue
6eissn
0147-6513issn
1090-2414pii
0147-6513(84)90011-3journal_volume
8pub_type
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journal_title:Ecotoxicology and environmental safety
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journal_title:Ecotoxicology and environmental safety
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journal_title:Ecotoxicology and environmental safety
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journal_title:Ecotoxicology and environmental safety
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doi:10.1016/j.ecoenv.2014.10.031
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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journal_title:Ecotoxicology and environmental safety
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2011.04.027
更新日期:2011-09-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.1998.1749
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2016.06.024
更新日期:2016-10-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.07.017
更新日期:2018-10-30 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2015.05.027
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(77)90035-5
更新日期:1977-09-01 00:00:00
abstract::Effects of carbofuran commercial formulation on oxidative stress parameters were studied in carps (Cyprinus carpio) exposed to 50µg/L for 7 and 30 days under rice field and laboratory conditions. Thiobarbituric acid reactive substance (TBARS) levels were increased in the brain of fish after 7 and 30 days under rice fi...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2013.12.012
更新日期:2014-03-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2016.01.020
更新日期:2016-06-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.01.050
更新日期:2018-05-30 00:00:00
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journal_title:Ecotoxicology and environmental safety
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2015.02.031
更新日期:2015-06-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/s0147-6513(02)00046-5
更新日期:2003-02-01 00:00:00
abstract::The aim of this research is to synthesize magnetite nanoparticles, using Persicaria bistorta root extract as the reducing agent, and to test its adsorption properties in the treatment of rosewater distillation wastewater. Taking advantage of Taguchi method, effect of synthesis parameters, including molar concentration...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.09.032
更新日期:2018-12-15 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2003.11.002
更新日期:2004-06-01 00:00:00
abstract::Soil acts as a repository for many metals that human activity releases into the environment. Cadmium enters agricultural soils primarily from application of phosphate fertilizers and sewage sludge. Among soil bacteria, rhizobia have a great agronomic and environmental significance and are major contributors to a susta...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.07.125
更新日期:2018-12-15 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.2000.2036
更新日期:2001-05-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 评论,信件
doi:10.1016/j.ecoenv.2015.06.026
更新日期:2015-10-01 00:00:00
abstract::Bisphenol A (BPA) is widely distributed in the environment and human surroundings and is closely related to the occurrence of many chronic diseases including female infertility. Although BPA-induced granulosa cell apoptosis has been widely reported, the underlying mechanisms remain unknown. In this study, we evaluated...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.111429
更新日期:2021-01-15 00:00:00
abstract::Arsenic (As) contamination of rice grain is a serious problem worldwide. The objective of this study was to mitigate As toxicity and accumulation in hydroponically grown KDML105 rice seedlings using bacteria isolated from heavy metal-contaminated soils. Seven strains (KKU2500-1, -2, -3, -9, -12, -16 and -22) of 24 cad...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.06.080
更新日期:2018-10-30 00:00:00
abstract::The aim of this study was to use digestive enzyme activities in Gammarus fossarum as biomarkers during active biomonitoring. Standardised gammarids were transplanted for 7 days to five sites in the Riou Mort watershed contaminated by polymetallic pollution. This experiment was conducted on seven different dates from F...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2013.07.016
更新日期:2013-11-01 00:00:00