Effects of NiO inhalation on alveolar macrophages and the humoral immune systems of rats.

Abstract:

:To study the effects of inhaled NiO particles on alveolar macrophages and the humoral immune system, male Wistar rats were continuously exposed to NiO aerosols for 4 weeks and 4 months, respectively. Fractions of alveolar macrophages, granulocytes, and lymphocytes in lung lavages, number of polynucleated macrophages, size of macrophages, and phagocytic activity were determined. To test the effects on the humoral immune response sheep erythrocytes were injected, and the antiserum titer in blood and the portion of antibody forming cells in spleen were measured. Significant alterations were found in both systems at 100 and 200 micrograms Ni/m3 after 4 weeks of exposure and at 25 and 150 micrograms Ni/m3 after 4 months of exposure, respectively. The results demonstrate the usefulness of investigations on the humoral immune system and alveolar macrophages as sensitive parameters in detecting effects of NiO inhalation.

journal_name

Ecotoxicol Environ Saf

authors

Spiegelberg T,Kördel W,Hochrainer D

doi

10.1016/0147-6513(84)90011-3

subject

Has Abstract

pub_date

1984-12-01 00:00:00

pages

516-25

issue

6

eissn

0147-6513

issn

1090-2414

pii

0147-6513(84)90011-3

journal_volume

8

pub_type

杂志文章
  • Source, spatial distribution, and toxicity potential of Polycyclic Aromatic Hydrocarbons in sediments from Iran's environmentally hot zones, the Persian Gulf.

    abstract::Surface sediments, sampled from Iranian coast of the Persian Gulf (n = 134), were analyzed in order to track spatial distribution of PAHs and their related eco-hazards. The levels of PAHs were in the range of 1.98-814 ng g-1 dw and the region was lowly to moderately polluted. The profile of PAHs was mainly composed of...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2019.02.029

    authors: Aghadadashi V,Mehdinia A,Riyahi Bakhtiari A,Mohammadi J,Moradi M

    更新日期:2019-05-30 00:00:00

  • Added risk approach to derive maximum permissible concentrations for heavy metals: how to take natural background levels into account.

    abstract::A unified method is presented to derive maximum permissible concentrations (MPCs) of xenobiotic and naturally occurring substances. The method relies upon risk limitation expressed as the maximum potentially affected fraction of all possible species (PAFmax) in a component ecosystem, due to a bioavailable concentratio...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1006/eesa.1997.1534

    authors: Struijs J,van de Meent D,Peijnenburg WJ,van den Hoop MA,Crommentuijn T

    更新日期:1997-07-01 00:00:00

  • Enhanced removal of Cr(III)-EDTA chelates from high-salinity water by ternary complex formation on DETA functionalized magnetic carbon-based adsorbents.

    abstract::A novel amino-functionalized magnetic adsorbent (Fe3O4@C@DETA) was developed for adsorption of Cr(III) and Cr(III)-EDTA from wastewater. Fe3O4@C@DETA were successfully prepared by modification of Fe3O4@C with diethylenediamine (DETA), which exhibits a core-shell structure and sufficient saturation magnetization. Fe3O4...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.111858

    authors: Wang J,Chen Y,Sun T,Saleem A,Wang C

    更新日期:2021-02-01 00:00:00

  • Brominated flame retardant (BFRs) and Dechlorane Plus (DP) in paired human serum and segmented hair.

    abstract::Brominated flame retardants (BFRs) and Dechlorane Plus (DP) were measured in both human hair and paired serum samples from a cohort of university students in South China. Segmental analysis was conducted to explore gender difference and the relationships between the hair and serum. The concentrations of total PBDEs in...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2017.09.047

    authors: Qiao L,Zheng XB,Yan X,Wang MH,Zheng J,Chen SJ,Yang ZY,Mai BX

    更新日期:2018-01-01 00:00:00

  • Application of ethylene diurea (EDU) in assessing the response of a tropical soybean cultivar to ambient O₃: nitrogen metabolism, antioxidants, reproductive development and yield.

    abstract::The present study deals with assessment of response of a tropical soybean cultivar to O3 in relation to photosynthetic pigments, chlorophyll fluorescence kinetics, antioxidative capacity, N assimilation enzymes, metabolites, growth and yield using ethylene diurea (EDU) given as a soil drench (400) ppm at an interval o...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2014.10.031

    authors: Rai R,Agrawal M,Kumar Choudhary K,Agrawal SB,Emberson L,Büker P

    更新日期:2015-02-01 00:00:00

  • Antibiotics promoted the recovery of Microcystis aeruginosa after UV-B radiation at cellular and proteomic levels.

    abstract::Elevated UV-B radiation due to ozone layer depletion may prevent the growth of bloom-forming cyanobacteria in aquatic environments, while antibiotic contaminants may cause effects opposite to that of UV-B due to hormesis. This study investigated the influence of a quaternary antibiotic mixture on Microcystis aeruginos...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2019.110080

    authors: Jiang Y,Liu Y,Zhang J,Gao B

    更新日期:2020-03-01 00:00:00

  • Residual phytotoxicity of parthenium: Impact on some winter crops, weeds and soil properties.

    abstract::Phytotoxic effects of parthenium residues incorporation and parthenium-infested rhizospheric soil on emergence and seedling growth of winter crops (wheat and canola) and weed species (wild oat and canary grass) were examined in different pot studies. In first experiment, parthenium whole plant residues were incorporat...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2015.08.019

    authors: Khaliq A,Aslam F,Matloob A,Hussain S,Tanveer A,Alsaadawi I,Geng M

    更新日期:2015-12-01 00:00:00

  • Carcinogen soil radon enrichment in a geothermal area: Case of Güzelçamlı-Davutlar district of Aydın city, western Turkey.

    abstract::Radon gas is noble gas formed from the normal radioactive decay series of 238U. Uranium is present in almost all rocks but enriched in silica-rich rocks like granites, gneisses, schists, volcanics, pegmatites, migmatites. The study area extends over metamorphic, volcanic, and clastic sedimentary rocks. Soil radon was ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.111466

    authors: Aydar E,Diker C

    更新日期:2021-01-15 00:00:00

  • Perfluorinated chemicals in blood of residents in Wenzhou, China.

    abstract::Perfluorinated compounds (PFCs) are persistent organic pollutants ubiquitously distributed in the environment and human populations. Here we report PFC concentrations in the residents of Wenzhou City, which is characterized as the 'Footwear Capital' of China. Specifically, fifty serum samples collected from workers in...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2011.04.027

    authors: Zhang W,Lin Z,Hu M,Wang X,Lian Q,Lin K,Dong Q,Huang C

    更新日期:2011-09-01 00:00:00

  • Altered challenge response in whitefish subchronically exposed in areas polluted by bleached kraft mill effluents.

    abstract::Exposure to impaired water quality, as in bleached kraft mill effluents (BKMEs), has recently been demonstrated to impair the ability of fish to elicit an acute stress response. Acute stress caused by catching is, in most field studies, an unavoidable incident that may markedly affect physiological functions. Consiste...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1006/eesa.1998.1749

    authors: Lappivaara J,Oikari A

    更新日期:1999-03-01 00:00:00

  • Impact of perinatal bisphenol A and 17β estradiol exposure: Comparing hormone receptor response.

    abstract::Hormonal regulation controls mammary gland (MG) development. Therefore some hormone-related factors can disrupt the early phases of MGs development, making the gland more susceptible to long term modifications in its response to circulating hormones. Endocrine disruptors, such as bisphenol A (BPA), are able to cause a...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2019.109918

    authors: Leonel ECR,Campos SGP,Guerra LHA,Bedolo CM,Vilamaior PSL,Calmon MF,Rahal P,Amorim CA,Taboga SR

    更新日期:2020-01-30 00:00:00

  • Effects of sodium pentaborate pentahydrate exposure on Chlorella vulgaris growth, chlorophyll content, and enzyme activities.

    abstract::Sodium pentaborate pentahydrate (SPP) is a rare mineral. In this study, SPP was synthesized from boric acid and borax through low-temperature crystallization, and its effects on the growth of the alga, Chlorella vulgaris (C. vulgaris) were assessed. The newly synthesized SPP was characterized by chemical analysis, X-r...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2016.06.024

    authors: Chen X,Pei Y

    更新日期:2016-10-01 00:00:00

  • Assessing off-target cytotoxicity of the field lampricide 3-trifluoromethyl-4-nitrophenol using novel lake sturgeon cell lines.

    abstract::Lampricides are currently being applied to streams and rivers to control the population of sea lamprey, an invasive species, in the Great Lakes. The most commonly used lampricide agent used in the field is 3-trifluoromethyl-4-nitrophenol (TFM), which targets larval sea lamprey in lamprey-infested rivers and streams. T...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2018.07.017

    authors: Vo NTK,Moore LC,Spiteri KW,Hanner R,Wilkie MP,DeWitte-Orr SJ

    更新日期:2018-10-30 00:00:00

  • Characterization of an epsilon-class glutathione S-transferase involved in tolerance in the silkworm larvae after long term exposure to insecticides.

    abstract::This study assessed the effect of the pesticides on activity and expression of glutathione S-transferases (GSTs) in the midgut of the silkworm after intense selections by phoxim and fenpropathrin for five and four generations, respectively. GSTs activity towards cumene hydroperoxide (CHP), a substrate of GSH-dependent...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2015.05.027

    authors: Zhou L,Fang SM,Huang K,Yu QY,Zhang Z

    更新日期:2015-10-01 00:00:00

  • Induction of hepatic microsomal enzymes by diuron, phenobenzuron, and metabolites in rats.

    abstract::Microsomal liver enzymes are induced in rats which are fed a diet containing 1000 ppm of phenobenzuron, a phenylurea herbicide, for 7 days: All parameters measured are about 50% higher than control values. This increase is lower after 14 feeding days. Diuron and 3,4-dichloroaniline have a similar, although lower, effe...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/0147-6513(77)90035-5

    authors: Corthay J,Medilanski P,Benakis A

    更新日期:1977-09-01 00:00:00

  • Carbofuran promotes biochemical changes in carp exposed to rice field and laboratory conditions.

    abstract::Effects of carbofuran commercial formulation on oxidative stress parameters were studied in carps (Cyprinus carpio) exposed to 50µg/L for 7 and 30 days under rice field and laboratory conditions. Thiobarbituric acid reactive substance (TBARS) levels were increased in the brain of fish after 7 and 30 days under rice fi...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2013.12.012

    authors: Clasen B,Leitemperger J,Murussi C,Pretto A,Menezes C,Dalabona F,Marchezan E,Adaime MB,Zanella R,Loro VL

    更新日期:2014-03-01 00:00:00

  • Application of quantitative structure-property relationship analysis to estimate the vapor pressure of pesticides.

    abstract::The application of molecular descriptors in describing Quantitative Structure Property Relationships (QSPR) for the estimation of vapor pressure (VP) of pesticides is of ongoing interest. In this study, QSPR models were developed using multiple linear regression (MLR) methods to predict the vapor pressure values of 16...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2016.01.020

    authors: Goodarzi M,Coelho Ldos S,Honarparvar B,Ortiz EV,Duchowicz PR

    更新日期:2016-06-01 00:00:00

  • Use of portable X-ray fluorescence spectroscopy and geostatistics for health risk assessment.

    abstract::Laboratory analysis of trace metals using inductively coupled plasma (ICP) spectroscopy is not cost effective, and the complex spatial distribution of soil trace metals makes their spatial analysis and prediction problematic. Thus, for the health risk assessment of exposure to trace metals in soils, portable X-ray flu...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2018.01.050

    authors: Yang M,Wang C,Yang ZP,Yan N,Li FY,Diao YW,Chen MD,Li HM,Wang JH,Qian X

    更新日期:2018-05-30 00:00:00

  • Comparison of rates of direct and indirect migration of phosphorus flame retardants from flame-retardant-treated polyester curtains to indoor dust.

    abstract::In this study, the pathways for migration of phosphorus flame retardants (PFRs), tris(1,3-dichloroisopropyl) phosphate (TDCPP) and tricresyl phosphate (TCsP) which were detected from curtains often, from flame-retardant-treated polyester curtains to indoor dust were investigated. Two possible migration pathways were c...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2018.11.052

    authors: Tokumura M,Ogo S,Kume K,Muramatsu K,Wang Q,Miyake Y,Amagai T,Makino M

    更新日期:2019-03-01 00:00:00

  • Electrochemical oxidation of indanthrene blue dye in a filter-press flow reactor and toxicity analyses with Raphidocelis subcapitata and Lactuca sativa.

    abstract::Alternative routes to degrade dyes are of crucial importance for the environment. Hence, we report the electrochemical removal of indanthrene blue by using a boron-doped diamond anode, focusing on the toxicity of the treated solutions. Different operational conditions were studied, such as current density (5, 10, and ...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.110659

    authors: Dória AR,Pupo M,Santos GOS,Vilar DDS,Torres NH,Romanholo Ferreira LF,Cavalcanti EB,Eguiluz KIB,Salazar-Banda GR

    更新日期:2020-07-15 00:00:00

  • Exposure of Daphnia magna to trichloroethylene (TCE) and vinyl chloride (VC): evaluation of gene transcription, cellular activity, and life-history parameters.

    abstract::Trichloroethylene (TCE) is a ubiquitous contaminant classified as a human carcinogen. Vinyl chloride (VC) is primarily used to manufacture polyvinyl chloride and can also be a degradation product of TCE. Very few data exist on the toxicity of TCE and VC in aquatic organisms particularly at environmentally relevant con...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2015.02.031

    authors: Houde M,Douville M,Gagnon P,Sproull J,Cloutier F

    更新日期:2015-06-01 00:00:00

  • Lethal and subchronic effects of 2,4,6-trinitrotoluene (TNT) on Enchytraeus albidus in spiked artificial soil.

    abstract::The effects of 2,4,6-trinitrotoluene (TNT) exposure in spiked artificial soil on the survival and reproduction rate of the white potworm Enchytraeus albidus were studied. Based on the initial concentrations, TNT in freshly spiked soil decreased enchytraeid survival (21-day LC(50)=422+/-63 (SD)mg/kg, N=3) and fecundity...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/s0147-6513(02)00046-5

    authors: Dodard SG,Renoux AY,Powlowski J,Sunahara GI

    更新日期:2003-02-01 00:00:00

  • Green synthesis and optimization of nano-magnetite using Persicaria bistorta root extract and its application for rosewater distillation wastewater treatment.

    abstract::The aim of this research is to synthesize magnetite nanoparticles, using Persicaria bistorta root extract as the reducing agent, and to test its adsorption properties in the treatment of rosewater distillation wastewater. Taking advantage of Taguchi method, effect of synthesis parameters, including molar concentration...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2018.09.032

    authors: Azadi F,Karimi-Jashni A,Zerafat MM

    更新日期:2018-12-15 00:00:00

  • Impact of nitrophenols on the photosynthetic electron transport chain and ATP content in Nostoc muscorum and Chlorella vulgaris.

    abstract::Concentration-dependent inhibition of the photosynthetic electron transport chain (photosystem I (PS I), photosystem II (PS II) and whole chain reaction) and ATP content was observed in Nostoc muscorum and Chlorella vulgaris grown with o-nitrophenol, m-nitrophenol, or 2,4-dinitrophenol. Although the extents of inhibit...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2003.11.002

    authors: Umamaheswari A,Venkateswarlu K

    更新日期:2004-06-01 00:00:00

  • Protective effects of farnesol on a Rhizobium strain exposed to cadmium.

    abstract::Soil acts as a repository for many metals that human activity releases into the environment. Cadmium enters agricultural soils primarily from application of phosphate fertilizers and sewage sludge. Among soil bacteria, rhizobia have a great agronomic and environmental significance and are major contributors to a susta...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2018.07.125

    authors: Nunes T,Cardoso P,Freitas R,Figueira E

    更新日期:2018-12-15 00:00:00

  • Acetylcholinesterase inhibition in the threeridge mussel (Amblema plicata) by chlorpyrifos: implications for biomonitoring.

    abstract::The effects of chlorpyrifos, an organophosphorus insecticide, were examined on the activity of the nervous system enzyme acetylcholinesterase (AChE) in the threeridge mussel Amblema plicata in a 24-day laboratory test. Thirty-six mussels in each of seven treatments (18 mussels per duplicate) were exposed to chlorpyrif...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1006/eesa.2000.2036

    authors: Doran WJ,Gregory Cope W,Rada RG,Sandheinrich MB

    更新日期:2001-05-01 00:00:00

  • Response to the Commentary on "Arsenic mobility in the arsenic-contaminated Yangzonghai Lake in China".

    abstract::This is the response to "Commentary on 'Arsenic mobility in the arsenic-contaminated Yangzonghai Lake in China' by Changliang Yang et al. [Ecotoxicology and Environmental Safety, 107(2014)321-327]" (by Jing Chen et al.). To doubts and questions raised by Chen et al., we give further explanations and provide more relev...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 评论,信件

    doi:10.1016/j.ecoenv.2015.06.026

    authors: Li S,Yang C,Liu K

    更新日期:2015-10-01 00:00:00

  • Bisphenol A induces apoptosis through GPER-dependent activation of the ROS/Ca2+-ASK1-JNK pathway in human granulosa cell line KGN.

    abstract::Bisphenol A (BPA) is widely distributed in the environment and human surroundings and is closely related to the occurrence of many chronic diseases including female infertility. Although BPA-induced granulosa cell apoptosis has been widely reported, the underlying mechanisms remain unknown. In this study, we evaluated...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2020.111429

    authors: Huang M,Huang M,Li X,Liu S,Fu L,Jiang X,Yang M

    更新日期:2021-01-15 00:00:00

  • Mitigation of arsenic toxicity and accumulation in hydroponically grown rice seedlings by co-inoculation with arsenite-oxidizing and cadmium-tolerant bacteria.

    abstract::Arsenic (As) contamination of rice grain is a serious problem worldwide. The objective of this study was to mitigate As toxicity and accumulation in hydroponically grown KDML105 rice seedlings using bacteria isolated from heavy metal-contaminated soils. Seven strains (KKU2500-1, -2, -3, -9, -12, -16 and -22) of 24 cad...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2018.06.080

    authors: Thongnok S,Siripornadulsil W,Siripornadulsil S

    更新日期:2018-10-30 00:00:00

  • Temporal patterns of digestive enzyme activities and feeding rate in gammarids (Gammarus fossarum) exposed to inland polluted waters.

    abstract::The aim of this study was to use digestive enzyme activities in Gammarus fossarum as biomarkers during active biomonitoring. Standardised gammarids were transplanted for 7 days to five sites in the Riou Mort watershed contaminated by polymetallic pollution. This experiment was conducted on seven different dates from F...

    journal_title:Ecotoxicology and environmental safety

    pub_type: 杂志文章

    doi:10.1016/j.ecoenv.2013.07.016

    authors: Dedourge-Geffard O,Charron L,Hofbauer C,Gaillet V,Palais F,Lacaze E,Geffard A,Geffard O

    更新日期:2013-11-01 00:00:00