Abstract:
:The commitment of non-dividing cells (in G0) to enter division can be studied using primary cultures of lymphocytes. The cells are stable in G0 unless stimulated by mitogen such as concanavalin A (Con A). Commitment to enter the division cycle depends on the expression of gene(s) induced by Con A and the synthesis of p53 protein correlates with this commitment step. I show here that in unstimulated cells, a second form of p53 is synthesized and is restricted to G0.
journal_name
Naturejournal_title
Natureauthors
Milner Jdoi
10.1038/310143a0subject
Has Abstractpub_date
1984-07-12 00:00:00pages
143-5issue
5973eissn
0028-0836issn
1476-4687journal_volume
310pub_type
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