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The distribution of some proopiomelanocortin-related peptides in the pituitary gland of the rainbow trout, Salmo gairdneri.

Abstract：

:Acid extracts of neurointermediate lobe (NIL) and pars distalis (PD) of the pituitary gland of the rainbow trout were radioimmunoassayed for alpha-melanocyte-stimulating hormone (alpha-MSH), beta-melanocyte-stimulating hormone (beta-MSH), adrenocorticotrophin (ACTH), and endorphin. The majority of the alpha-MSH, beta-MSH, and endorphin was present in the NIL; the small amount of these peptides present in the PD may be native to this lobe, or may be due to slight contamination with NIL material--it is not possible to distinguish between these possibilities at present. All the ACTH was present in the PD. These results support the hypothesis that throughout the vertebrates proopiomelanocortin is cleaved to smaller peptides in the NIL than it is in the PD.

journal_name

Gen Comp Endocrinol

journal_title

General and comparative endocrinology

authors

Rodrigues K,Sumpter JP

doi

10.1016/0016-6480(83)90062-x

subject

Has Abstract

pub_date

1983-09-01 00:00:00

pages

454-9

issue

3

eissn

0016-6480

issn

1095-6840

journal_volume

51

pub_type

杂志文章

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