Abstract:
:The cell transforming ability of asbestos dust was investigated using C3H10T 1/2 murine fibroblasts. In a series of experiments both crocidolite and amosite caused no increase in the number of transformed foci over that seen in cultures from untreated cells. The dusts, were, however, capable of augmenting the oncogenic effect of benzo[a]pyrene (BP). This putative synergistic effect was evident when fibres and chemicals were added to cultures as simple mixtures and when BP was adsorbed to the surface of the fibres.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Brown RC,Poole A,Fleming GTdoi
10.1016/0304-3835(83)90071-xsubject
Has Abstractpub_date
1983-03-01 00:00:00pages
221-7issue
2eissn
0304-3835issn
1872-7980pii
0304-3835(83)90071-Xjournal_volume
18pub_type
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