Mechanism of haemolysis by chrysotile fibres.

Abstract:

:Haemolysis by chrysotile fibres may be related to an adsorption of the red blood cell (RBC) membranes on the fibres and not to an interaction between magnesium (Mg) from the fibres and sialic acid from RBC. This was demonstrated using neuraminidase (NANASE)-treated RBC and Mg-depleted chrysotile fibres. The mechanism may be extended to other minerals since a relationship can be obtained between the ability of various minerals to adsorb liposomes of dipalmitoyl phosphatidylcholine (DPPC) and their haemolytic activity.

journal_name

Toxicol Lett

journal_title

Toxicology letters

authors

Jaurand MC,Magne L,Bignon J

doi

10.1016/0378-4274(83)90217-5

subject

Has Abstract

pub_date

1983-02-01 00:00:00

pages

205-11

issue

2-3

eissn

0378-4274

issn

1879-3169

pii

0378-4274(83)90217-5

journal_volume

15

pub_type

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