Pleural plaques in asbestosis: effect of Candida albicans.

Abstract:

:Effect of chrysotile dust alone or together with Candida albicans administered intratracheally in guinea pigs was studied in the genesis of pleural plaques over a period of 12 months. A significant increase of mucopolysaccharides, phosphorus, calcium and -SH content was detected in pleural fluid of animals treated with chrysotile and Candida albicans together than in those treated with chrysotile or Candida albicans alone. The results suggest that an infection of Candida albicans accentuates the effect of chrysotile by altering the biochemical parameters preceding to the formation of pleural plaques.

journal_name

Toxicol Lett

journal_title

Toxicology letters

authors

Saxena KC,Srivastava L,Ali S,Dogra RK

doi

10.1016/0378-4274(82)90207-7

subject

Has Abstract

pub_date

1982-10-01 00:00:00

pages

175-8

issue

3-4

eissn

0378-4274

issn

1879-3169

pii

0378-4274(82)90207-7

journal_volume

13

pub_type

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