Abstract:
:When stimulated by the feeding of ethylenethiourea for a period of 6 months, dog thyroid glands increased to approximately 30 times their normal size. Not only follicular cells but also C cells had hyperplastic and hypertrophic features, compared with normal controls there was in the C cells a marked decrease in secretory granules immunoreactive for calcitonin. Furthermore, vesicular inclusions of various sizes and dilated nuclear enveloped, which showed a positive immunoreaction for calcitonin, were observed in the C cells. These findings indicate that the antithyroid drug interferes with synthesis of calcitonin by C cells probably by inhibiting the conversion of a larger precursor to calcitonin by C cells, probably by inhibiting the conversion of a larger precursor to calcitonin.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Kameda Ydoi
10.1007/BF00214684subject
Has Abstractpub_date
1982-01-01 00:00:00pages
315-8issue
2eissn
0302-766Xissn
1432-0878journal_volume
225pub_type
杂志文章abstract::Striated rootlets in ciliated cells are conical banded structures composed of longitudinally aligned filaments. The formation of striated rootlets during ciliognesis in the human oviduct epithelium was studied by electron microscopy. Primitive rootlets appeared at the proximal side of basal bodies before or at the sam...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050905
更新日期:1997-10-01 00:00:00
abstract::Quantitative studies on the population of the gonadotropic cells in the pituitary of adult male rats were performed after trypsic dissociation of the pituitary glands and immunoenzymatic staining with anti-beta-LH or anti-beta-FSH antisera. Number, area and extinction of labelled cells were measured by use of an image...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217273
更新日期:1982-01-01 00:00:00
abstract::Central projections of the nervus terminalis (n.t.) in the goldfish were investigated using cobalt- and horseradish peroxidase-tracing techniques. Single n.t. fibers were identified after unilateral application of cobalt chloride-lysine to the rostral olfactory bulb. The central course and branching patterns of indivi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218095
更新日期:1986-01-01 00:00:00
abstract::In the present study, immunogold labeling of ultrathin sections of rat small intestine and liver has been used to obtain insights into the ultrastructural localization and possible functions of annexins. In enterocytes, annexins II, IV, and VI are found at the periphery of the core of each microvillus and of the rootl...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00414181
更新日期:1994-11-01 00:00:00
abstract::In this immunocytochemical study we investigated the distribution of nervous structures in the lower lip of adult rats. The region is characterized by a rich cutaneous and mucosal sensory innervation originating from terminal branches of the trigeminal system. Lower lip innervation was investigated by detection of the...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051348
更新日期:1999-08-01 00:00:00
abstract::The comparatively simple Caenorhabditis elegans intestine fulfills many of the complex functions of the mammalian digestive tract, liver, and fat tissues, while also having roles in pathogen defense, immunity, and longevity. In this review, we describe the structure of the C. elegans gut and how it develops from the e...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-019-03036-4
更新日期:2019-09-01 00:00:00
abstract::During normal development of many vertebrate species, substantial numbers of neurons in the central and peripheral nervous system undergo naturally occurring (or programmed) cell death. For example, approximately 50% of spinal motoneurons degenerate and die at a time when these cells are establishing synaptic connecti...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050690
更新日期:1996-11-01 00:00:00
abstract::Agitation of villi evokes reflexes that affect the motility of the guinea-pig small intestine. NK1 receptor endocytosis was used to investigate the possible involvement of tachykinins acting on neuronal NK1 receptors in these reflexes. Segments of guinea-pig ileum were incubated at 37 degrees C in Krebs physiological ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051032
更新日期:1998-04-01 00:00:00
abstract::We have previously shown that the chromogranin A (CgA)-derived peptide catestatin (CST: hCgA352-372) inhibits nicotine-induced secretion of catecholamines from the adrenal medulla and chromaffin cells. In the present study, we seek to determine whether CST regulates dense core (DC) vesicle (DCV) quanta (catecholamine ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2956-1
更新日期:2019-04-01 00:00:00
abstract::NdWFamide is an Aplysia cardioexcitatory tri-peptide containing D-tryptophan. To investigate the roles of this peptide, we examined the immunohistochemical distribution of NdWFamide-positive neurons in Aplysia tissues. All the ganglia of the central nervous system (CNS) contained NdWFamide-positive neurons. In particu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0707-3
更新日期:2003-04-01 00:00:00
abstract::The livers of Xenopus laevis, grouped by chronological age (0.5, 2 and 3 yrs), were studied electron microscopically. Ultrastructurally most of the melanin granules in the mature female liver showed an internal structure similar to the melanin granules of the oocytes. The hepatic melanin granules of immature females a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220293
更新日期:1977-12-19 00:00:00
abstract::Thy-1, a glycophosphatidylinositol-linked glycoprotein of the outer membrane leaflet, has been described in myofibroblasts of several organs. Previous studies have shown that, in fetal liver, Thy-1 is expressed in a subpopulation of ductular/progenitor cells. The aim of this study has been to investigate whether the l...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0437-z
更新日期:2007-09-01 00:00:00
abstract::In situ hybridisation and immunohistochemistry analyses have shown that the Ciona intestinalis tumour necrosis factor alpha gene (CiTNFalpha), which has been previously cloned and sequenced, is expressed either during the inflammatory pharynx response to lipopolysaccharide (LPS) or during the swimming larval phase of ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-0993-5
更新日期:2010-08-01 00:00:00
abstract::Hepatic stellate cells become activated and aquire contractility on being cultured. In order to characterize the morphology of contracted and relaxed stellate cells, we performed light- and electron-microscopic analyses of cultured stellate cells on collagen gels. Incubation of stellate cells with medium alone, 10 nM ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050717
更新日期:1996-12-01 00:00:00
abstract::Conventional two-dimensional cell monolayers do not provide the geometrical, biochemical and mechanical cues found in real tissues. Cells in real tissues interact through chemical and mechanical stimuli with adjacent cells and via the extracellular matrix. Such a highly interconnected communication network extends alo...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-013-1589-7
更新日期:2013-04-01 00:00:00
abstract::The effect of vascular endothelial growth factor (VEGF165) on the chorioallantoic membrane (CAM) of 13-day-old chick embryos was studied. The factor was applied in doses of 0.5-4 micrograms for a period of up to 4 days. Macroscopical, histological and immunohistological studies were carried out. The localization of th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327997
更新日期:1993-10-01 00:00:00
abstract::The electrocyte fibers in the gymnotid Sternarchus albifrons are highly differentiated myelinated axons which exhibit several types of nodes of Ranvier and characteristically short internode lengths. In the present study, regeneration of the electrocyte fibers following removal of the tail was examined by electron mic...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233869
更新日期:1980-01-01 00:00:00
abstract::The retina of the distal and proximal lens-bearing complex ocelli are composed of pigmented sensory cells and long pigmented cells. A ciliary sheath from each sensory cell, together with the processes of long pigmented cells, extends through the vitreous layer as far as the capsule that envelops the lens. Each ciliary...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219415
更新日期:1976-07-30 00:00:00
abstract::The ultrastructure of the calcium-sensitive (Ca-s) (PAS-positive) cells of the pars intermedia was investigated in eels kept in hypo- and hyperosmotic environments. Although the cells were moderately active in fresh water (FW), they were highly stimulated in deionized water (DW) and displayed an enlarged Golgi apparat...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00210015
更新日期:1981-01-01 00:00:00
abstract::In the compound eye of the locust, Locusta, the cross-sectional area of the rhabdoms increases at "dusk" by 4.7-fold due to the rapid assembly of new microvillar membrane, and decreases at "dawn" by a corresponding amount as a result of pinocytotic shedding from the microvilli. The rhabdoms at night have more and long...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214807
更新日期:1982-01-01 00:00:00
abstract::Transplantation of a small fragment of the ileum beneath the kidney capsule in syngenic mice results in the formation of a cyst lined with proliferating intestinal epithelium. The duration of the cell cycle in the epithelium was determined (using tritiated thymidine and the FLM method) as 14.5 h, as compared with 11.5...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221125
更新日期:1977-02-02 00:00:00
abstract::Germ cells of human fetuses aged 7-13 weeks were studied. Dense fibrous material called nuage was found in the cytoplasm of human fetal germ cells. The nuage increased in frequency in the germ cells during the interval studied. In oogonia the nuage occurred much more frequently than in spermatogonia and the frequency ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00209243
更新日期:1978-11-09 00:00:00
abstract::PC12 pheochromocytoma cells treated with nerve growth factor (NGF) in combination with high concentrations of the activators of adenylate cyclase, forskolin or cholera toxin, become more neuron-like in size than cells treated with NGF or with activators of adenylate cyclase alone. Cells treated simultaneously with NGF...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215430
更新日期:1987-07-01 00:00:00
abstract::A tissue-engineered heart valve can be an alternative to a prosthetic valve in heart valve replacement; however, it is not fully efficient in terms of long-lasting functionality, as leaflets in engineered valves do not possess the trilayered native leaflet structure. Previously, we developed a flat, trilayered, orient...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03241-6
更新日期:2020-11-01 00:00:00
abstract::Light and electron microscopic studies, including the use of the vital dyes trypan blue and acridine orange, indicate that the topical application of precocene II rapidly triggers degenerative processes in the corpora allata (CA) leading within a few days to the virtual disappearance of the parenchymal cells of these ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234326
更新日期:1979-11-01 00:00:00
abstract::We have tested the suggestion that the reported increase, in hypoxic rats, in the number of lung endocrine cells immunoreactive for the regulatory peptide CGRP is caused by an accumulation of peptide within the cells which renders them more detectable, rather than by a real increase in proliferation. The incorporation...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00338049
更新日期:1992-04-01 00:00:00
abstract::The adenohypophysial primordium of Xenopus laevis tadpoles at stages 33/34 to 46 (Nieuwkoop and Faber, 1956) were examined immunohistologically for alpha-MSH, beta-MSH and ACTH. beta-MSH was demonstrated from stage 37/38 onwards, and alpha-MSH from stage 39. No signs of ACTH production were detected. alpha-MSH and bet...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00231955
更新日期:1977-05-16 00:00:00
abstract::This study investigates the relationship between pituitary LHRH responsiveness and the depletion of LH in pubertal rats. The anterior pituitaries of 7-week-old rats of both sexes were stimulated for a maximum of 24 h with either a continuous, or pulsatile exposure to LHRH in vitro. Immunohistochemical examination reve...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218057
更新日期:1986-01-01 00:00:00
abstract::The technique of cobalt sulfide precipitation combined with Timm's sulfide-silver method for intensification of heavy metals was used to delineate the retino-hypothalamic projection of the rat. Freshly isolated rat brains were dissected and a solution of cobaltous chloride was applied to one of the cut optic nerves. S...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219728
更新日期:1976-04-28 00:00:00
abstract::A multilamellate body (MLB), bearing close resemblance to an array of annulate lamellae, has been observed in several adenohypophysial cell types of the teleost, Hemihaplochromis philander. In longitudinal section, each MLB comprises a ladder-like row of 12-50 sausage-shaped profiles, termed lamellae. A few lamellae i...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221372
更新日期:1976-10-06 00:00:00