Analysis of recombination in mammalian cells using SV40 genome segments having homologous overlapping termini.

Abstract:

:Segments of SV40 DNA having homologous overlapping termini recombine to produce viable genomes in monkey cells. Frequencies of recombination on either side of a deletion marker are non-random; replication and palindromes do not appear to be essential. Since recombination involves host enzymes, a suitable system has been devised for analysing host cell recombination functions.

journal_name

Nucleic Acids Res

journal_title

Nucleic acids research

authors

Upcroft P,Carter B,Kidson C

doi

10.1093/nar/8.12.2725

subject

Has Abstract

pub_date

1980-06-25 00:00:00

pages

2725-36

issue

12

eissn

0305-1048

issn

1362-4962

journal_volume

8

pub_type

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