Repair of x-ray-induced deoxyribonucleic acid single-strand breaks in xth mutants of Escherichia coli.

Abstract:

:An exonuclease III-deficient strain of Escherichia coli K-12, BW2001 (xthA11), was unable to perform rapid repair of X-ray-induced deoxyribonucleic acid single-strand breaks and appeared to have a defect in the priming of the 3'-termini necessary for initiation of repair synthesis at the breaks. This defect cannot be explained solely by the lack of exonuclease III activity, because other xth mutants tested, including a deletion mutant, repaired radiation-induced strand breaks at close to the normal rate.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Seeberg E,Steinum AL

doi

10.1128/JB.141.3.1424-1427.1980

subject

Has Abstract

pub_date

1980-03-01 00:00:00

pages

1424-7

issue

3

eissn

0021-9193

issn

1098-5530

journal_volume

141

pub_type

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