Abstract:
:Virtually the whole region of the mobile dispersed genetic element mdg1 including the direct repeats that frame mdg1 /1/ is transcribed. The end of the transcriptional unit is located within the direct repeat. Although the transcription of mdg1 is symmetric, one direction is transcribed preferentially and is a full-length transcript represented by approximately 29S poly(A)+RNA. Besides it, approximately 15S poly(A)+RNA is present in the cytoplasm of culture cells which corresponds to the 3'-part of 29S RNA and possibly to a small region near the 5'-end of the latter. The major fraction of mdg1 transcripts is present in the fraction of free cytoplasmic RNP particles while only 10-20% are recovered in polysomes. In this respect, mdg1 is similar to mdg3 and quite different from two single-copy genes transcripts of which are almost completely recovered in polysomes. The relationship between mobile dispersed genetic elements and endogeneous viral genomes is discussed.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Ilyin Y,Chmeliauskaite VG,Kulguskin VV,Georgiev GPdoi
10.1093/nar/8.22.5347subject
Has Abstractpub_date
1980-11-25 00:00:00pages
5347-61issue
22eissn
0305-1048issn
1362-4962journal_volume
8pub_type
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