Mobile dispersed genetic element MDG1 of Drosophila melanogaster: transcription pattern.

Abstract:

:Virtually the whole region of the mobile dispersed genetic element mdg1 including the direct repeats that frame mdg1 /1/ is transcribed. The end of the transcriptional unit is located within the direct repeat. Although the transcription of mdg1 is symmetric, one direction is transcribed preferentially and is a full-length transcript represented by approximately 29S poly(A)+RNA. Besides it, approximately 15S poly(A)+RNA is present in the cytoplasm of culture cells which corresponds to the 3'-part of 29S RNA and possibly to a small region near the 5'-end of the latter. The major fraction of mdg1 transcripts is present in the fraction of free cytoplasmic RNP particles while only 10-20% are recovered in polysomes. In this respect, mdg1 is similar to mdg3 and quite different from two single-copy genes transcripts of which are almost completely recovered in polysomes. The relationship between mobile dispersed genetic elements and endogeneous viral genomes is discussed.

journal_name

Nucleic Acids Res

journal_title

Nucleic acids research

authors

Ilyin Y,Chmeliauskaite VG,Kulguskin VV,Georgiev GP

doi

10.1093/nar/8.22.5347

subject

Has Abstract

pub_date

1980-11-25 00:00:00

pages

5347-61

issue

22

eissn

0305-1048

issn

1362-4962

journal_volume

8

pub_type

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