Transganglionic transport of D-aspartate from cochlear nucleus to cochlea--a quantitative autoradiographic study.

abstract：:Cochlear outer hair cell (OHC) electromotility is associated with the cell's lateral wall. The lateral wall contains two distinct membranes: the plasma membrane (PM) and the subsurface cisternae (SSC). We explored biophysical characteristics of these lipid structures using membrane-specific fluorescent dyes. We have p...

journal_title：Hearing research

authors： Oghalai JS,Tran TD,Raphael RM,Nakagawa T,Brownell WE

更新日期：1999-09-01 00:00:00

abstract：:A single-channel hydromechanical model of the human cochlea with nonlinear feedback on the membrane is introduced. The piezoelectric transducers for displacement measurement and force exertion on the membrane are constructed of PVF2 in the bimorph bending type. The passive response shows high-frequency slopes of about...

journal_title：Hearing research

authors： Lechner TP

更新日期：1993-04-01 00:00:00

abstract：:The inferior colliculus occupies a central position in ascending and descending auditory pathways. A substantial proportion of its neurons are GABAergic, and these neurons contribute to intracollicular circuits as well as to extrinsic projections to numerous targets. A variety of types of evidence - morphology, physio...

journal_title：Hearing research

authors： Schofield BR,Beebe NL

更新日期：2019-05-01 00:00:00

abstract：:Recordings were made from 185 neurons in the primary auditory cortex of cats in the age range of 15 to 297 days. A comparison was made between the tuning for click repetition-rate and for amplitude modulation-frequency of a noise burst on the basis of temporal Modulation Transfer Functions (tMTF). 90 of the 185 units ...

journal_title：Hearing research

authors： Eggermont JJ

更新日期：1993-02-01 00:00:00

abstract：:The effect of glutathione co-therapy on the expression of gentamicin ototoxicity was tested in pigmented guinea pigs. The first group of animals was injected with gentamicin (100 mg/kg body weight/day) for two weeks followed by 10 weeks of rest. A second group received glutathione by gastric gavage immediately prior t...

journal_title：Hearing research

authors： Garetz SL,Altschuler RA,Schacht J

更新日期：1994-06-15 00:00:00

abstract：:Admittance at the tympanic membrane was measured in one ear of 73 chicks in 8 age groups between 1 and 150 days post-hatch. Admittance at 7 frequencies (0.66-1.8 kHz) was calculated from measurements of the magnitude and phase angle of sound pressure in front of the tympanic membrane. The results show that admittance ...

journal_title：Hearing research

authors： Saunders JC,Relkin EM,Rosowski JJ,Bahl C

更新日期：1986-01-01 00:00:00

abstract：:We obtained just-noticeable differences (jnds) for the intensity of pure tones following a forward masker. The masker was a 100-ms burst of narrow-band noise centered at 1000 Hz presented at 90 dB SPL; the pure-tone signal was at 1000 Hz and was 25 ms in duration. The masker-signal delay was 100 ms. Under these condit...

journal_title：Hearing research

authors： Zeng FG,Turner CW,Relkin EM

更新日期：1991-10-01 00:00:00

abstract：:Neural auditory thresholds in the guinea pig can be temporarily improved by up to 6 dB about 2 min after the cessation of an moderately intense low-frequency tone (Kirk and Patuzzi, 1997). We have measured changes in the f2-f1 distortion product otoacoustic emission (DPOAE) and low-frequency microphonic potential in s...

journal_title：Hearing research

authors： Kirk DL,Moleirinho A,Patuzzi RB

更新日期：1997-10-01 00:00:00

abstract：:An anatomically based model of cochlear neuron electrophysiology has been developed and used to interpret the physiological responses of the auditory neuron to electrical summation and refractory pulse-pair stimuli. For summation pulses, the summation time constant, tau(sum), indicates the ability of the membrane to h...

journal_title：Hearing research

authors： Cartee LA

更新日期：2006-05-01 00:00:00

abstract：:Light microscopy and immunohistochemical analyses of a freshly prepared human cochlea, removed at meningioma skull base surgery, were performed with particular emphasis on synaptophysin (SY) reactivity. Synaptophysin, a 38-kDa glycoprotein, is one of the most abundant integral membrane proteins of small presynaptic ve...

journal_title：Hearing research

authors： Khalifa SA,Friberg U,Illing RB,Rask-Andersen H

更新日期：2003-11-01 00:00:00

abstract：:Auditory brainstem responses (ABR) from ten normal (3 males, 7 females) and ten environmentally sound deprived CBA/J mice (6 males, 4 females) were elicited by 30 dB HL click stimuli delivered via specially constructed, matched insert earphones. The mice were tested at 44-49 days of age under chloral hydrate sedation ...

journal_title：Hearing research

authors： Evans WJ,Webster DB,Cullen JK Jr

更新日期：1983-06-01 00:00:00

abstract：:Although speech understanding is highly variable amongst cochlear implants (CIs) subjects, the remarkably high speech recognition performance of many CI users is unexpected and not well understood. Numerous factors, including neural health and degradation of the spectral information in the speech signal of CIs, likely...

journal_title：Hearing research

authors： Zheng Y,Escabí M,Litovsky RY

更新日期：2017-08-01 00:00:00

abstract：:To create experimental lesions localized to the low frequency region of the organ of Corti, a cryoprobe was applied to the apical area of 37 cochleas from 26 adult chinchillas. Twenty cochleas were exposed to single applications of a cryoprobe for 2.5, 3.0 and 3.5 min; 17 cochleas were exposed to two applications of 1...

journal_title：Hearing research

authors： Brown JN,Nuttall AL

更新日期：1987-01-01 00:00:00

abstract：:In cases of sudden, reversible hearing loss where perilymphatic fistulas are thought to be the cause, a multitude of causes have been postulated. These include perilymphatic pressure changes, Simmons' double-break theory, perilymphatic hemorrhage, pneumolabyrinth, and others. This study was proposed to explore the rol...

journal_title：Hearing research

authors： Foster PK,Luebke AE

更新日期：2002-05-01 00:00:00

abstract：:A novel immunocytochemical method was used to determine whether the sound-damaged adult quail ear can repair its tectorial membrane (TM) and to compare the repair in quail to that in chicks. Birds were exposed to an octave band noise with a center frequency of 1.5 kHz at 116 dB SPL for 4 h. The chicks were grouped bas...

journal_title：Hearing research

authors： Adler HJ,Niemiec AJ,Moody DB,Raphael Y

更新日期：1995-06-01 00:00:00

abstract：:Cochlear implant insertion should be as least traumatic as possible in order to reduce trauma to the cochlear sensory structures. The force applied to the cochlea during array insertion should be controlled to limit insertion-related damage. The relationship between insertion force and histological traumatism remains ...

journal_title：Hearing research

authors： De Seta D,Torres R,Russo FY,Ferrary E,Kazmitcheff G,Heymann D,Amiaud J,Sterkers O,Bernardeschi D,Nguyen Y

更新日期：2017-02-01 00:00:00

abstract：:Spongiform lesions of the gerbil cochlear nucleus are reduced in number and extent by rearing in acoustic isolation compared with rearing while exposed to normal colony low-frequency background noise. This study tested whether rearing under exposure to noise bands of moderate intensity would increase the number and ex...

journal_title：Hearing research

authors： McGinn MD,Faddis BT

更新日期：1994-12-01 00:00:00

abstract：:In ears in which cochlear efferent pathways were cut and with testing done under anaesthetic conditions that preclude middle ear muscle activity (so as to examine the "intrinsic" effects of loud sound on the cochlea without any confounding effect of efferent pathways to the auditory periphery), atraumatic background w...

journal_title：Hearing research

authors： Rajan R

更新日期：2006-03-01 00:00:00

abstract：:When using bone vibrator transducers for clinical measurements, the transfer of energy from the bone driver depends on the impedance match between the driver and the load (human mastoid or otherwise) to which the driver will be applied. Current clinical calibration methods are incapable of quantifying this impedance m...

journal_title：Hearing research

authors： Weece R,Allen J

更新日期：2010-05-01 00:00:00

abstract：:We have investigated the morphometric changes in the cochlear nucleus of patients who had undergone cochlear implantation following profound deafness. The brain stems of 11 adult patients who had undergone implantation and four non-implanted control cases with varying degrees of hearing loss were studied. The volumes ...

journal_title：Hearing research

authors： Chao TK,Burgess BJ,Eddington DK,Nadol JB Jr

更新日期：2002-12-01 00:00:00

abstract：:Action potentials recorded extracellularly from neurons within the caudal cochlear nuclei of developing cats exhibited distinctive temporal characteristics (i.e., rhythmic responses) in response to long-duration acoustic stimuli including both tone and noise bursts. Unlike the homogeneous response characteristics of a...

journal_title：Hearing research

authors： Walsh EJ,McGee J

更新日期：1988-11-01 00:00:00

abstract：:Congenital hearing loss (HL) affects about 1 in every 500 infants. Among those affected more than half are caused by genetic mutations. According to the cellular sites affected by mutations in the cochlea, deafness genes could be classified into three major groups: those affecting the function of hair cells and synaps...

journal_title：Hearing research

authors： Zhang L,Wu X,Lin X

更新日期：2020-09-01 00:00:00

abstract：:Projections from the posterior thalamus and medial geniculate body were labeled retrogradely with wheat germ agglutinin conjugated to horseradish peroxidase injected into the rat, cat, and squirrel monkey inferior colliculus. Neurons were found ipsilaterally in the (1) medial division of the medial geniculate body, (2...

journal_title：Hearing research

authors： Winer JA,Chernock ML,Larue DT,Cheung SW

更新日期：2002-06-01 00:00:00

abstract：:Blind cave fish employ superficial neuromasts to detect currents [Baker, C.F. and J.C. Montgomery, J. Comp. Physiol. A 184 (1999) 519-527]. Briefly exposing fish to calcium-free water significantly reduces the ability of the fish to perform rheotaxis (i.e., to orient properly in currents). Spontaneous recovery to cont...

journal_title：Hearing research

authors： Berg A,Watson GM

更新日期：2002-12-01 00:00:00

abstract：:There is evidence that pentobarbital, a commonly used anesthetic, can affect neuronal activity, but its effects on particular neurons of the dorsal cochlear nucleus (DCN) are not well known. Bursting (complex spiking) spontaneous activity has been observed in the DCN in brain slice preparations and in recordings from ...

journal_title：Hearing research

authors： Chen K,Godfrey DA

更新日期：2000-11-01 00:00:00

abstract：:One can construct narrow bands of noise that contain delays of either the envelope, the phase, or the carrier separately or in combination. Delayed and undelayed noises will have identical spectra if, and only if, both the envelope and the phase undergo delays of the same magnitude. To study lateralization of these si...

journal_title：Hearing research

authors： Amenta CA 3rd,Trahiotis C,Bernstein LR,Nuetzel JM

更新日期：1987-01-01 00:00:00

abstract：:The distribution of neurotensin-containing cell bodies and fibers has been observed in the central and peripheral nervous system, including sensory ganglia, but no description has been found in the peripheral auditory system. Here, we investigated the presence of neurotensin immunoreactivity in the cochlea of the adul...

journal_title：Hearing research

authors： Gomide VC,de Francisco AC,Chadi G

更新日期：2005-07-01 00:00:00

abstract：:Exposure of the vestibulo-cochlear anastomosis in the cat allows single-unit recording of afferent fibers originating from inner hair cells and olivocochlear efferent fibers to the outer hair cells. Comparison of data obtained from individual animals show similarities in absolute threshold and dynamic range between th...

journal_title：Hearing research

authors： Liberman MC

更新日期：1988-07-15 00:00:00

abstract：:Blind cave fish use the lateral line sensory system to detect nearby objects. The fish responds to sudden perturbations in the water column by initiating startle responses in which they swim more rapidly. Normal startle responses disappear after trauma caused by a single 15 s immersion in calcium free water, but retur...

journal_title：Hearing research

authors： Repass JJ,Watson GM

更新日期：2001-04-01 00:00:00

abstract：:Auditory brainstem implants (ABIs) can restore useful hearing to persons with deafness who cannot benefit from cochlear implants. However, the quality of hearing restored by ABIs rarely is comparable to that provided by cochlear implants in persons for whom those are appropriate. In an animal model, we evaluated eleme...

journal_title：Hearing research

authors： McCreery D,Yadev K,Han M

更新日期：2018-06-01 00:00:00