Cerebral cortex and amino acid neurotransmitters: higher levels of aspartic acid but not GABA in the frontal cortex of the rat.

abstract：:Many similarities exist between the inhibitory influence of estrogen on food intake (FI) and body weight (BWt) in female rats and the effect of lateral hypothalamic (LH) lesions on energy balance. Thus, a possible interaction of small electrolytic LH lesions (0.8 mA/10 sec) with hormone-dependent changes in FI, BWt an...

journal_title：Brain research bulletin

authors： Nance DM,Gorski RA

更新日期：1978-09-01 00:00:00

abstract：:Degenerating terminals were mapped by the Fink-Heimer method after lateral or fourth ventricular administration of 6-hydroxydopamine (60OHDA). This method marks dopaminergic terminals and has the advantage that noradrenergic terminals are not stained. Fink-Heimer stained degeneratig terminals were seen bilaterally in ...

journal_title：Brain research bulletin

authors： Hedreen J

更新日期：1980-07-01 00:00:00

abstract：:Fourteen patients with high- (n = 7) and low-dose (n = 7) benzodiazepine (BDZ) dependency presented predominantly with anxious and depressive neurotic symptoms which caused long-term BDZ medication. Their BDZ dependency was characterized by giving preference to the abuse of benzodiazepines with long elimination half-l...

journal_title：Brain research bulletin

authors： Schmauss C,Apelt S,Emrich HM

更新日期：1987-09-01 00:00:00

abstract：:The use of neurons induced from stem cells has been introduced as an effective strategy for promoting peripheral nerve regeneration (PNR). The evolution and role of native denervated Schwann cells (SCs) were often ignored when exploring the mechanisms underlying neural transplantation therapy for PNR. The aim of this ...

journal_title：Brain research bulletin

authors： Zheng Y,Huang C,Liu F,Lin H,Niu Y,Yang X,Zhang Z

更新日期：2018-05-01 00:00:00

abstract：:Windup, the frequency dependent build-up of spinal neuronal responses is an electrophysiological model of the development of the central sensitization in the chronic pain states. NR2B subunit containing NMDA-type glutamate receptors are implicated in the windup of dorsal horn neurons, while their role at the motoneuro...

journal_title：Brain research bulletin

authors： Kocsis P,Kovács G,Farkas S,Horváth C,Szombathelyi Z,Tarnawa I

更新日期：2004-08-30 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a degenerative disease with a progressive loss of motor neurons in the central nervous system (CNS). However, there are unsolved problems with the therapies for this disease. α-Lipoic acid (LA) is a natural, universal antioxidant capable of scavenging hydroxyl radicals as well as...

journal_title：Brain research bulletin

authors： Wang T,Cheng J,Wang S,Wang X,Jiang H,Yang Y,Wang Y,Zhang C,Liang W,Feng H

更新日期：2018-06-01 00:00:00

abstract：:The effects of autophagy on neuronal damage can be positive or detrimental negative. Through establishing a model of fetal rat cortical neuron hydraulic shock injury, dipotassium bisperoxo (picolinoto) oxovanadate (V) [bpv(pic)] was used to inhibit PTEN at different time points post-injury and autophagy level after ne...

journal_title：Brain research bulletin

authors： Yu H,Shao J,Huang R,Guan Y,Li G,Chen S,Zhou F,Yao Q,Shen J

更新日期：2020-12-01 00:00:00

abstract：:The purpose of this study was to determine whether elevated levels of 3,4-dihydroxyphenylacetic acid (DOPAC), the major metabolite of dopamine (DA) in the brain, could decrease the DA content in the striatum. Levels of DA were determined by high pressure liquid chromatography with electrochemical detection (HPLC-EC) i...

journal_title：Brain research bulletin

authors： Shiekhattar R,Ghasemzadeh MB,Adams RN

更新日期：1992-12-01 00:00:00

abstract：:The present study was conducted to evaluate plasma levels of monoamine neurotransmitter metabolites in spontaneous recurrences of methamphetamine psychosis (i.e., flashbacks). The subjects were 50 physically healthy females comprised of 25 who experienced flashbacks (flashbackers), 18 who did not experienced methamphe...

journal_title：Brain research bulletin

authors： Yui K,Goto K,Ikemoto S,Ishiguro T

更新日期：1997-01-01 00:00:00

abstract：:Electrical stimulation has been shown to have neuroprotective effects on ganglion cells and photoreceptors in axotomized and dystrophic retinas from Royal College of Surgeons (RCS) rats. This study determined whether electrical stimulation also has a neuroprotective effect on cells in the inner nuclear layer (INL) of ...

journal_title：Brain research bulletin

authors： Schmid H,Herrmann T,Kohler K,Stett A

更新日期：2009-04-06 00:00:00

abstract：:Various hypotheses are reviewed concerning the mechanisms of feeding induced by insulin or 2DG. New data are presented to show that elevated plasma ketone levels are not sufficient to suppress 2DG feeding, suggesting that nourishment of the brain either does not occur or is not sufficient to stop 2DG feeding. We find ...

journal_title：Brain research bulletin

authors： Rowland NE,Bellush LL,Carlton J

更新日期：1985-06-01 00:00:00

abstract：:A newly developed technique employing the retrograde transport of horseradish peroxidase combined with immunocytochemistry is used to identify the cells of origin of descending spinal pathways and their putative neurotransmitters. With this technique the brainstem origins of descending serotonergic (5HT) pathways to t...

journal_title：Brain research bulletin

authors： Bowker RM,Westlund KN,Coulter JD

更新日期：1982-07-01 00:00:00

abstract：:Cocaine is a major stimulant drug which can have rewarding and locomotor activating effects. It is used by non-addicts to enhance concentration and performance in a work or social setting. It was suggested that cocaine may amplify the impact of mood and sensory stimulation on behaviour. Here we tested whether cocaine ...

journal_title：Brain research bulletin

authors： Pum ME,Rubio AR,Carey RJ,Silva MA,Müller CP

更新日期：2011-02-28 00:00:00

abstract：:Rats were tested in the elevated plus-maze test of anxiety after a probe injection of chlordiazepoxide (CDP 5 mg/kg) following short-term (5 days) or long-term (20 days) pretreatment with 5 or 20 mg/kg/day. After short-term pretreatment with either dose, the probe dose had anxiolytic effects (it increased the % number...

journal_title：Brain research bulletin

authors： File SE,Baldwin HA,Aranko K

更新日期：1987-11-01 00:00:00

abstract：:Unit responses to chorda tympani stimulation in urethane anesthetized rats were characterized by response latency and frequency following ability. One hundred and fifty one units responded with constant latencies, mean: 16.9 msec, S.D.: 7.8 msec. Responses recorded from within the superior salivatory nucleus (SSN) had...

journal_title：Brain research bulletin

authors： Eisenman JS

更新日期：1983-06-01 00:00:00

abstract：:Developmental malformations of cortex have been shown to co-occur with language, learning, and other cognitive deficits in humans. Rodent models have repeatedly shown that animals with such developmental malformations have deficits related to auditory processing and learning. More specifically, freeze-lesion induced m...

journal_title：Brain research bulletin

authors： Threlkeld SW,McClure MM,Bai J,Wang Y,LoTurco JJ,Rosen GD,Fitch RH

更新日期：2007-03-15 00:00:00

abstract：:Stimulation of the dorsal frontal cortex (area 10, FCtx) evoked two negative waves with short latencies (N1 and N2) followed by a large, longlasting positive wave (P) in the ventromedial nucleus (VMH) as well as in the more dorsal structures in the hypothalamus and the ventral thalamus. Since the N1 followed high freq...

journal_title：Brain research bulletin

authors： Ohta M,Oomura Y

更新日期：1979-03-01 00:00:00

abstract：:Sporadic Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder affected by amyloid and vascular pathogenesis. Brain insulin resistance (BIR) has been suggested as one of the pathomechanisms of sporadic AD. We investigated how the amyloid and vascular pathogenesis of AD interacts with BIR. We examined...

journal_title：Brain research bulletin

authors： Choi BR,Seo JH,Back DB,Han JS,Choi DH,Kwon KJ,Shin CY,Lee J,Kim HY

更新日期：2020-05-01 00:00:00

abstract：:Adult male Sprague-Dawley rats were made paraplegic by a complete transection of the spinal cord at lower thoracic level. One week later they were transplanted, below the level of the section, with a cell suspension prepared from the raphe region of 14-day embryos. After survival periods of 10 days to 1 year, the anim...

journal_title：Brain research bulletin

authors： Privat A,Mansour H,Rajaofetra N,Geffard M

更新日期：1989-01-01 00:00:00

abstract：:Chronic social stress and/or pharmacological treatments differentially modulate the expression of c-Fos, a marker of neuronal activity, in subregions of the rat brain. Here, we examined the effect of the atypical antipsychotic Clozapine (Clz) (20 mg/kg/day for 3 weeks) on the neuronal activation pattern of c-Fos prote...

journal_title：Brain research bulletin

authors： Stanisavljević A,Perić I,Bernardi RE,Gass P,Filipović D

更新日期：2019-10-01 00:00:00

abstract：:The aim of this magnetic resonance imaging study was to find a geometrical characterization of the deeper part of the corpus callosum. Its shape was studied in 12 middle-aged persons free of white matter pathology. Profiles of curvatures were measured showing that this surface was close to a minimal one, especially at...

journal_title：Brain research bulletin

authors： Stievenart JL,Iba-Zizen MT,Tourbah A,Lopez A,Thibierge M,Abanou A,Cabanis EA

更新日期：1997-01-01 00:00:00

abstract：:The Lurcher (Lc/+) mutant mouse is characterized by a considerable atrophy of the cerebellum due to a massive loss of cerebellar Purkinje and granule cells, as well as of neurons from the inferior olivary nucleus. In this study the effects of a therapeutic combination of amantadine, thiamine and L-tryptophan on the se...

journal_title：Brain research bulletin

authors： Le Marec N,Hébert C,Botez MI,Botez-Marquard T,Marchand L,Reader TA

更新日期：1999-01-15 00:00:00

abstract：:The neuronal networks of the frontal lobe that represent motor or executive memories are probably the same networks that cooperate with other cerebral structures in the temporal organization of behavior. The prefrontal cortex, at the top of the perception-action cycle, plays a critical role in the mediation of conting...

journal_title：Brain research bulletin

authors： Fuster JM

更新日期：2000-07-15 00:00:00

abstract：:We have previously identified the neurotransmitter vasoactive intestinal peptide (VIP) in nerve fibers of the immature rat ovary and showed that it stimulates steroid release by a mechanism involving increased synthesis of the components of the cholesterol side-chain cleavage enzyme complex. The present experiments we...

journal_title：Brain research bulletin

authors： Advis JP,Ahmed CE,Ojeda SR

更新日期：1989-04-01 00:00:00

abstract：:Simple tandem repeats represent more than 1% of the human genome: occasionally they exhibit intergenerational expansibility and are associated with neuromuscular diseases. In transgenic mice the same sequences elicit similar symptoms, but do not expand. We have searched for di-, tri-, and tetra-repeats in the publishe...

journal_title：Brain research bulletin

authors： Astolfi P,Bellizzi D,Losso MA,Sgaramella V

更新日期：2001-10-01 00:00:00

abstract：:Sex differences are prominent influences on spatial performance. One of the most common tasks to assess sex differences in spatial navigation in rodents is the Morris water task (MWT). In this task rats swim in a pool of water to locate a hidden platform employing the topographical relationships among the distal visua...

journal_title：Brain research bulletin

authors： Faraji J,Metz GA,Sutherland RJ

更新日期：2010-01-15 00:00:00

abstract：:In the present study, multi-electrode array recording was used to examine dorsal horn activity following stimulation of primary afferents in a rat dorsal root attached-spinal cord slice preparation. The multi-electrode array probe was placed under the dorsal horn slice and local field potentials evoked by stimulation ...

journal_title：Brain research bulletin

authors： Yu F,Zhao ZY,He T,Yu YQ,Li Z,Chen J

更新日期：2017-05-01 00:00:00

abstract：:The effects of two diketopiperazines, Cyclo (His-Pro) (CHP) and Cyclo (Asp-Phe) (CAP), on striatal extracellular levels of dopamine (DA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5-HIAA) were examined using in vivo microdialysis in anaesthetized rats. Treatment with ...

journal_title：Brain research bulletin

authors： Kaakkola S,Wurtman RJ

更新日期：1993-01-01 00:00:00

abstract：:Norepinephrine (NE) and dopamine (DA) levels and turnover were measured in 17 discrete brain regions of Swiss-Webster (NIH) mice made aggressive by prolonged isolation. The NE steady state level was significantly lower in olfactory tubercle and substantia nigra and significantly higher in the septal area of the aggres...

journal_title：Brain research bulletin

authors： Tizabi Y,Massari VJ,Jacobowitz DM

更新日期：1980-01-01 00:00:00

abstract：:Excitatory amino acid transporters (EAATs) represent a group of high affinity glutamate transporters that are involved in the regulation of extracellular glutamate levels at glutamatergic synapses. EAAT proteins have been found on neurons as well as on glia cells where they act synergistically to remove the released g...

journal_title：Brain research bulletin

authors： Gesemann M,Maurer CM,Neuhauss SC

更新日期：2010-10-30 00:00:00