Progesterone and estrogens in rat brain: modulation of GABA (gamma-aminobutyric acid) receptor activity.

Abstract:

:Our data indicate that estrogens and progesterone can regulate the number of GABA receptors (as detected by [3H]muscimol binding assay) in rat brain. Both hormones act in selected areas. The extent of the effect (up to 160% increase) and the number of areas responsive suggest that sex hormones may play a very important role in the regulation of the functions of GABAergic transmission in the central nervous system.

journal_name

Eur J Pharmacol

authors

Maggi A,Perez J

doi

10.1016/0014-2999(84)90205-x

subject

Has Abstract

pub_date

1984-08-03 00:00:00

pages

165-8

issue

1-2

eissn

0014-2999

issn

1879-0712

pii

0014-2999(84)90205-X

journal_volume

103

pub_type

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