Aminoacid constitution of two gastrins isolated from Zollinger-Ellison tumour tissue.

Abstract:

:Two peptides which are potent stimulants of gastric acid secretion are isolated from Zollinger-Ellison tumour tissue. They have aminoacid constitutions identical with those of human gastrin types I and II as isolated from human antral mucosa, and they are present in similar proportions. Their electrophoretic and chromatographic behaviour corresponds to that of human gastrins. Evidence is presented in respect of the one isolated in greater amount that its aminoacid sequence is probably identical with that of human gastrin type I.

journal_name

Gut

journal_title

Gut

authors

Gregory RA,Tracy HJ,Agarwal KL,Grossman MI

doi

10.1136/gut.10.8.603

subject

Has Abstract

pub_date

1969-08-01 00:00:00

pages

603-8

issue

8

eissn

0017-5749

issn

1468-3288

journal_volume

10

pub_type

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