RNA-dependent DNA-polymerase activity in human milk.


:A simple method is described for testing milk specimens from nursing mothers for the presence of RNA-dependent DNA-polymerase activity. Positive results were obtained in five of 137 women (3.6%) without a family history of breast cancer, and in six of 31 women (19.3%) with a family history of breast cancer.


J Med Microbiol


McFarlane ES,Ryan SM,Mann E




Has Abstract


1975-08-01 00:00:00












  • Cronobacter sakazakii induces necrotizing enterocolitis by regulating NLRP3 inflammasome expression via TLR4.

    abstract::Introduction. Neonatal infection with Cronobacter sakazakii can cause severe intestinal damage and necrotizing enterocolitis (NEC). The inflammasome and Toll-like receptors mediate intestinal damage caused by other intestinal pathogens causing NEC, but the exact mechanism is unclear.Aim. We evaluated the molecular mec...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Chen Z,Zhang Y,Lin R,Meng X,Zhao W,Shen W,Fan H

    更新日期:2020-05-01 00:00:00

  • Prevalence of multidrug-resistant Helicobacter pylori in Bulgaria.

    abstract::The aim of this study was to evaluate the presence and prevalence of multidrug antibacterial resistance in Helicobacter pylori in Bulgaria from 2005 to 2008. The resistance in 828 untreated adults, 124 treated adults and 105 untreated children was, respectively, 26.5, 50.8 and 16.2% for metronidazole; 18.4, 45.2 and 1...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Boyanova L

    更新日期:2009-07-01 00:00:00

  • Prevalence and virulence characteristics of enteroaggregative Escherichia coli in a case-control study among patients from Iran.

    abstract::Enteroaggregative Escherichia coli (EAEC) is an important agent of diarrhoeal diseases worldwide. The role of EAEC virulence factors in the clinical outcome of infection is not completely defined. This case-control study investigated the prevalence of EAEC, its virulence genes and the antimicrobial resistance profile ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Bafandeh S,Haghi F,Zeighami H

    更新日期:2015-05-01 00:00:00

  • Detection of clonal KPC-2-producing Klebsiella pneumoniae ST258 in Korea during nationwide surveillance in 2011.

    abstract::This study analysed the characteristics and genetic similarity of recent Klebsiella pneumoniae carbapenemase (KPC-2)-producing Klebsiella pneumoniae isolates from Korea. Recent laboratory surveillance detected an increase in carbapenemase-producing Enterobacteriaceae in Korea. A total of 6 KPC-2-producing K. pneumonia...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Yoo JS,Kim HM,Yoo JI,Yang JW,Kim HS,Chung GT,Lee YS

    更新日期:2013-09-01 00:00:00

  • Phenotypic and genotypic traits and epidemiological implication of Vibrio cholerae O1 and O139 strains in India during 2003.

    abstract::During 2003, Vibrio cholerae O1 Ogawa was the predominant serotype among diarrhoeal patients admitted to different hospitals in India. With the exception of 3 strains from Kolkata, none of 172 strains examined exhibited resistance to tetracycline, but 45.7 % showed reduced susceptibility to ciprofloxacin. Extensive mo...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Chatterjee S,Ghosh K,Raychoudhuri A,Pan A,Bhattacharya MK,Mukhopadhyay AK,Ramamurthy T,Bhattacharya SK,Nandy RK

    更新日期:2007-06-01 00:00:00

  • Identification of urinary pathogens by the RAPIDEC ur system.

    abstract::A commercial method (RAPIDEC ur; bioMérieux UK Ltd, Basingstoke) and an in-house scheme based on conventional tests were compared for the identification of 179 commonly encountered gram-negative urinary pathogens. The methods identified correctly to genus level 97% and 84% of organisms, respectively. RAPIDEC ur was su...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Batchelor BI

    更新日期:1995-07-01 00:00:00

  • Effects of mucopolysaccharides on penicillin-induced lysis of Staphylococcus aureus.

    abstract::Effects of four mucopolysaccharides and dextran sulphate on penicillin-induced lysis of Staphylococcus aureus FDA 209P were studied. Heparin and dextran sulphate inhibited lysis, whereas hyaluronic acid enhanced it. Chondroitin sulphates A and C had no effect. Incubation of S. aureus suspended in 0.03 M phosphate buff...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Kiriyama T,Miyake Y,Sugai M,Kobayashi K,Yoshiga K,Takada K,Suginaka H

    更新日期:1987-12-01 00:00:00

  • Coxsackie B virus-specific IgM antibody and myocardial infarction.

    abstract::The ELISA technique was shown to be group-specific for the detection of IgM antibodies against coxsackie B viruses, and probably against a wider range of enteroviruses. No evidence was obtained that recent coxsackie B-virus infection predisposes to myocardial infarction. ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Hannington G,Booth JC,Bowes RJ,Stern H

    更新日期:1986-06-01 00:00:00

  • Inhibition by amoeba-specific antiserum and by cytochalasin B of the cytopathogenicity of Naegleria fowleri in mouse embryo-cell cultures.

    abstract::Inhibitors of trophozoite motility and phagocytosis were used to investigate the mechanism of Naegleria fowleri cytopathogenicity in mouse-embryo (ME)-cell cultures. Amoebae that were immobilised and agglutinated by specific antiserum exhibited no cytopathic activity, although they remained alive and were in constant ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Brown T

    更新日期:1979-08-01 00:00:00

  • Severe case of Mediterranean spotted fever in Greece with predominantly neurological features.

    abstract::Rickettsia conorii is endemic in Greece, though only a few cases of infection have been published to date. The case of a 58-year-old man from northern Greece with a severe form of Mediterranean spotted fever and rapid neurological deterioration is presented here. The patient received antibiotic treatment with doxycycl...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Tzavella K,Hatzizisis IS,Vakali A,Mandraveli K,Zioutas D,Alexiou-Daniel S

    更新日期:2006-03-01 00:00:00

  • Biochemical characterisation, enteropathogenicity and antimicrobial resistance plasmids of clinical and environmental Aeromonas isolates.

    abstract::One hundred and eight strains of Aeromonas from clinical and environmental samples were speciated. Seven species were identified, the most prevalent of which was A. hydrophila. Experimental studies in an animal model with 36 representative strains of different species revealed that all strains could cause significant ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Chaudhury A,Nath G,Shukla BN,Sanyal SC

    更新日期:1996-06-01 00:00:00

  • Differential binding of Shiga toxin 2 to human and murine neutrophils.

    abstract::Shiga toxins (Stx1 and Stx2) are responsible for initiating haemolytic uraemic syndrome, a serious extraintestinal complication caused by enterohaemorrhagic Escherichia coli O157 : H7 infection in humans. Shiga toxins are classical AB(5)-type exotoxins, consisting of a globotriaosylceramide (Gb(3))-binding B subunit p...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Griener TP,Mulvey GL,Marcato P,Armstrong GD

    更新日期:2007-11-01 00:00:00

  • Effect of chlorhexidine gluconate on the adherence of Candida species to denture acrylic.

    abstract::The effect of pretreatment of denture acrylic with chlorhexidine gluconate on the subsequent adherence of Candida albicans GDH 2346 was measured in vitro. Adherence was significantly reduced by pretreatment with chlorhexidine; maximal inhibition was achieved by incubation at room temperature for 30 min in 2% chlorhexi...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: McCourtie J,MacFarlane TW,Samaranayake LP

    更新日期:1985-08-01 00:00:00

  • An in vitro and in vivo study on the synergistic effect and mechanism of itraconazole or voriconazole alone and in combination with tetrandrine against Aspergillus fumigatus.

    abstract::In this study, we investigated the in vitro antifungal effects of itraconazole/voriconazole (ITR/VRC) alone and in combination with tetrandrine (TET) against 23 clinical isolates of A. fumigatus using a chequerboard microdilution method. The dynamic antifungal effects of TET with ITR/VRC against A. fumigatus were asse...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Li SX,Song YJ,Zhang LL,Shi JP,Ma ZL,Guo H,Dong HY,Li YM,Zhang H

    更新日期:2015-09-01 00:00:00

  • Antimicrobial activity of lacticin 3,147 against clinical Clostridium difficile strains.

    abstract::Clostridium difficile-associated diarrhoea (CDAD) is the most common hospital-acquired diarrhoea, and is a major type of gastroenteritis infection in nursing homes and facilities for the elderly. In this study the antimicrobial activity of the two-component lantibiotic, lacticin 3,147, against a range of genetically d...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Rea MC,Clayton E,O'Connor PM,Shanahan F,Kiely B,Ross RP,Hill C

    更新日期:2007-07-01 00:00:00

  • Rapid Sepsityper in clinical routine: 2 years' successful experience.

    abstract::Introduction. Rapid identification of the causative agent of sepsis is crucial for patient outcomes.Aim. The Sepsityper sample preparation method enables direct microbial identification of positive blood culture samples via matrix-assisted laser desorption ionization/time-of-flight mass spectrometry (MALDI-TOF MS).Hyp...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Cordovana M,Zignoli A,Ambretti S

    更新日期:2020-12-01 00:00:00

  • Development of imipenem resistance in an Aeromonas veronii biovar sobria clinical isolate recovered from a patient with cholangitis.

    abstract::Several imipenem-susceptible and -resistant Aeromonas veronii biovar sobria isolates with different morphologies and antimicrobial susceptibilities recovered from bile samples of a patient with cholangitis were analysed. These isolates belonged to the same clone and the imipenem-resistant strains showed overexpression...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Sánchez-Céspedes J,Figueras MJ,Aspiroz C,Aldea MJ,Toledo M,Alperí A,Marco F,Vila J

    更新日期:2009-04-01 00:00:00

  • Improved rapid molecular diagnosis of multidrug-resistant tuberculosis using a new reverse hybridization assay, REBA MTB-MDR.

    abstract::Rapid diagnosis of multidrug-resistant tuberculosis (MDR-TB) is essential for the prompt initiation of effective second-line therapy to improve treatment outcome and limit transmission of this obstinate disease. A variety of molecular methods that enable the rapid detection of mutations implicated in MDR-TB have been ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Bang H,Park S,Hwang J,Jin H,Cho E,Kim DY,Song T,Shamputa IC,Via LE,Barry CE,Cho SN,Lee H

    更新日期:2011-10-01 00:00:00

  • Composition of staphylococcal bi-component toxins determines pathophysiological reactions.

    abstract::Staphylococcus aureus produces numerous bi-component toxins, e.g., Panton-Valentine leukocidin (Luk-PVL) and gamma-haemolysin, which consist of type S and F proteins. Previous studies showed that Luk-PVL induces inflammatory mediator release from human granulocytes that might reflect the in-vivo effects, e.g., dermone...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: König B,Prévost G,König W

    更新日期:1997-06-01 00:00:00

  • Allelic variation and prevalence of serum opacity factor among the Streptococcus suis population.

    abstract::Serum opacity factor of Streptococcus suis (OFS) has recently been identified as a virulence determinant of an S. suis strain. In this study, we investigated the prevalence and variations of the ofs gene among 108 S. suis isolates from diseased and healthy pigs, and human patients. PCR screening and sequencing analysi...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Takamatsu D,Osaki M,Tharavichitkul P,Takai S,Sekizaki T

    更新日期:2008-04-01 00:00:00

  • Molecular characterisation of the dominant UK methicillin-resistant Staphylococcus aureus strains, EMRSA-15 and EMRSA-16.

    abstract::Epidemic methicillin-resistant Staphylococcus aureus types 15 and 16 (EMRSA-15 and EMRSA-16) are the dominant types of MRSA found in UK hospitals, but accurate designation of strains has been difficult. Restriction fragment length polymorphism (RFLP) profiles of seven core virulence genes were used to classify unambig...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Moore PCL,Lindsay JA

    更新日期:2002-06-01 00:00:00

  • Biocompatible biodegradable polymeric antibacterial nanoparticles for enhancing the effects of a third-generation cephalosporin against resistant bacteria.

    abstract:PURPOSE:In the present study, enhancement of the the antibacterial activity of ceftriaxone against Gram-positive (meticillin-resistant Staphylococcus aureus; MRSA) and Gram-negative (Escherichia coli) bacteria with a biodegradable polymer was attempted. METHODOLOGY:MRSA and E. coli were collected and identified by bio...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Mushtaq S,Khan JA,Rabbani F,Latif U,Arfan M,Yameen MA

    更新日期:2017-03-01 00:00:00

  • Same-day antimicrobial susceptibility test using acoustic-enhanced flow cytometry visualized with supervised machine learning.

    abstract::Purpose. Antimicrobial susceptibility is slow to determine, taking several days to fully impact treatment. This proof-of-concept study assessed the feasibility of using machine-learning techniques for analysis of data produced by the flow cytometer-assisted antimicrobial susceptibility test (FAST) method we developed....

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Inglis TJJ,Paton TF,Kopczyk MK,Mulroney KT,Carson CF

    更新日期:2020-05-01 00:00:00

  • Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells.

    abstract::The fungal pathogen Cryptococcus neoformans has a predilection for the central nervous system (CNS), resulting in devastating meningoencephalitis. At present, it is unclear how C. neoformans traverses the blood-brain barrier (BBB) and causes CNS infection. The present study has examined and characterized the interacti...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Chen SHM,Stins MF,Huang SH,Chen YH,Kwon-Chung KJ,Chang Y,Kim KS,Suzuki K,Jong AY

    更新日期:2003-11-01 00:00:00

  • Characteristics of a pandemic clone of O3 : K6 and O4 : K68 Vibrio parahaemolyticus isolated in Beira, Mozambique.

    abstract::The genetic characteristics of Vibrio parahaemolyticus strains isolated in 2004 and 2005 in Mozambique were assessed in this study to determine whether the pandemic clone of V. parahaemolyticus O3 : K6 and O4 : K68 serotypes has spread to Mozambique. Fifty-eight V. parahaemolyticus strains isolated from hospitalized d...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Ansaruzzaman M,Chowdhury A,Bhuiyan NA,Sultana M,Safa A,Lucas M,von Seidlein L,Barreto A,Chaignat CL,Sack DA,Clemens JD,Nair GB,Choi SY,Jeon YS,Lee JH,Lee HR,Chun J,Kim DW

    更新日期:2008-12-01 00:00:00

  • Canine dermatophytosis caused by an anthropophilic species: molecular and phenotypical characterization of Trichophyton tonsurans.

    abstract::Microsporum canis is the most common species isolated from canine and feline dermatophytosis in the world. However, this study reports a rare case of canine dermatophytosis caused by the anthropophilic dermatophyte Trichophyton tonsurans in the city of Fortaleza, Ceará, Brazil. The fungal characterization was performe...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Brilhante RSN,Cordeiro RA,Gomes JMF,Sidrim JJC,Rocha MFG

    更新日期:2006-11-01 00:00:00

  • Bone resorbing activity of surface-associated material from Actinobacillus actinomycetemcomitans and Eikenella corrodens.

    abstract::The results of this study demonstrate that saline extracted surface-associated material (SAM) of Actinobacillus actinomycetemcomitans and Eikenella corrodens stimulates bone resorption at picomolar concentrations. Various inhibitors of known osteolytic mediators--indomethacin, interleukin-1 receptor antagonist (IL-1ra...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Meghji S,Wilson M,Barber P,Henderson B

    更新日期:1994-09-01 00:00:00

  • Antibody-independent protection against Pseudomonas aeruginosa infection in mice after treatment with a homologous strain vaccine.

    abstract::Formalin-killed cells of Pseudomonas aeruginosa strain M-24 elicited an antibody-independent protective effect against P. aeruginosa infection in mice. The effect was observed as early as 6 h after administration and 100% protection was obtained by 48 h. The protective effect could not be attributed to the production ...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Fujimura T,Suzuki T,Mitsuyama M,Saito H,Nomoto K

    更新日期:1989-02-01 00:00:00

  • Delineation of Stenotrophomonas maltophilia isolates from cystic fibrosis patients by fatty acid methyl ester profiles and matrix-assisted laser desorption/ionization time-of-flight mass spectra using hierarchical cluster analysis and principal component

    abstract::Stenotrophomonas maltophilia is an opportunist multidrug-resistant pathogen that causes a wide range of nosocomial infections. Various cystic fibrosis (CF) centres have reported an increasing prevalence of S. maltophilia colonization/infection among patients with this disease. The purpose of this study was to assess s...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Vidigal PG,Mosel F,Koehling HL,Mueller KD,Buer J,Rath PM,Steinmann J

    更新日期:2014-12-01 00:00:00

  • Phylogenetic analysis of partial VP7 gene of the emerging human group A rotavirus G12 strains circulating in Tunisia.

    abstract:PURPOSE:Group A rotavirus (RVA) is the leading cause of severe gastroenteritis in children younger than 5 years. The most common human G-types are G1-4 and G9. G12 genotype is currently emerging worldwide, becoming the sixth most prevalent RVA G-genotype. In Tunisia, an emergence of G12 RVA strains was observed. To und...

    journal_title:Journal of medical microbiology

    pub_type: 杂志文章


    authors: Moussa A,Fredj MBH,BenHamida-Rebaï M,Fodha I,Boujaafar N,Trabelsi A

    更新日期:2017-02-01 00:00:00