Loss of the penicillinase plasmid after treatment of Staphylococcus aureus with sodium dodecyl sulfate.

Abstract:

:Two strains of Staphylococcus aureus (PC1 and 196E), when grown in medium containing 0.002% sodium dodecyl sulfate (SDS), showed from 96.1 to 100% loss of the ability to produce penicillinase. Resistance to cadmium and zinc was lost concomitantly with the ability to produce penicillinase. A comparison of the rate of curing by SDS with the curing effects exerted by elevated temperature and ethidium bromide suggested that SDS is a more effective plasmid curing agent for susceptible strains of S. aureus than methods in use at present.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Sonstein SA,Baldwin JN

doi

10.1128/JB.109.1.262-265.1972

subject

Has Abstract

pub_date

1972-01-01 00:00:00

pages

262-5

issue

1

eissn

0021-9193

issn

1098-5530

journal_volume

109

pub_type

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