Preclinical radiobiology with pions: RBE--values for mouse skin damage as a function of single doses of pions.

abstract：:Four different thiol reagents: p-chloromercuribenzoic acid (pCMB), mercuric chloride (HgCl2), N-ethylmaleimide (NEM), and 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) were employed as agents modifying the transport of a hydrophilic and hydrophobic non-electrolyte spin labels: 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-o...

journal_title：Radiation and environmental biophysics

authors： Gwoździński K,Bartosz G,Leyko W

更新日期：1983-01-01 00:00:00

abstract：:Low-dose ionizing radiation (IR) responses remain an unresolved issue in radiation biology and risk assessment. Accurate knowledge of low-dose responses is important for estimation of normal tissue risk in cancer radiotherapy or health risks from occupational or hazard exposure. Cellular responses to low-dose IR appea...

journal_title：Radiation and environmental biophysics

authors： Langen B,Helou K,Forssell-Aronsson E

更新日期：2020-08-01 00:00:00

abstract：:C57Bl6-lacZ animals were exposed to a range of low dose-rate simulated solar particle event (sSPE) radiation at the NASA-sponsored Research Laboratory (NSRL) at Brookhaven National Laboratory (BNL). Peripheral blood was harvested from animals from 1 to 12 days after total body irradiation (TBI) to quantify the level o...

journal_title：Radiation and environmental biophysics

authors： Chang PY,Doppalapudi R,Bakke J,Wang A,Menda S,Davis Z

更新日期：2010-08-01 00:00:00

abstract：:Checkpoints are components of signalling pathways involved in genome stability. We analysed the putative dual functions of Rad17 and Chk1 as checkpoints and in DNA repair using mutant strains of Saccharomyces cerevisiae. Logarithmic populations of the diploid checkpoint-deficient mutants, chk1Delta/chk1Delta and rad17...

journal_title：Radiation and environmental biophysics

authors： Bracesco N,Candreva EC,Keszenman D,Sánchez AG,Soria S,Dell M,Siede W,Nunes E

更新日期：2007-11-01 00:00:00

abstract：:For radiation exposures employing targeted sources such as particle microbeams, the deposition of energy and dose will depend on the spatial heterogeneity of the sample. Although cell structural variations are relatively minor for two-dimensional cell cultures, they can vary significantly for fully differentiated tiss...

journal_title：Radiation and environmental biophysics

authors： Miller JH,Chrisler WB,Wang X,Sowa MB

更新日期：2011-08-01 00:00:00

abstract：:An extensive programme of experiments on transfer of radionuclides to aquatic species was conducted in the former USSR starting from the early 1950s. Only a few of these studies were made available in the English language literature or taken into account in international reviews of radionuclide behaviour in marine eco...

journal_title：Radiation and environmental biophysics

authors： Fesenko S,Fesenko E,Titov I,Karpenko E,Sanzharova N,Fonseca AG,Brown J

更新日期：2010-11-01 00:00:00

abstract：:Growth rates and cell diameters were determined from 12 species of plant roots exposed to a 60-Hertz (Hz) electric field of 360 Volts per meter (V/m) in an aqueous inorganic nutrient medium [conductivity: 0.07-0.09 Siemens per meter (S/m)]. The degree of growth depression ranged from zero to nearly 100 percent of cont...

journal_title：Radiation and environmental biophysics

authors： Inoue M,Miller MW,Carstensen EL,Brayman AA

更新日期：1985-01-01 00:00:00

abstract：:The method of iteratively reweighted least squares for the regression analysis of Poisson distributed chromosome aberration data is reviewed in the context of other fit procedures used in the cytogenetic literature. As an application of the resulting regression curves methods for calculating confidence intervals on do...

journal_title：Radiation and environmental biophysics

authors： Merkle W

更新日期：1983-01-01 00:00:00

abstract：:Beginning in 1950, people living on the banks of the Techa River received chronic low-dose-rate internal and external radiation exposures as a result of releases from the Mayak nuclear weapons plutonium production facility in the Southern Urals region of the Russian Federation. The Techa River cohort includes about 30...

journal_title：Radiation and environmental biophysics

authors： Krestinina L,Preston DL,Davis FG,Epifanova S,Ostroumova E,Ron E,Akleyev A

更新日期：2010-05-01 00:00:00

abstract：:A temporary increase in the incidence of infant leukaemia in Greece was reported by Petridou et al., which was attributed to in utero exposure to ionising radiation resulting from the Chernobyl accident. We performed a similar analysis based on the data of the German Childhood Cancer Registry in order to check whether...

journal_title：Radiation and environmental biophysics

authors： Steiner M,Burkart W,Grosche B,Kaletsch U,Michaelis J

更新日期：1998-07-01 00:00:00

abstract：:Growing hair follicles with their rapid cell proliferation would be expected to be sensitive organs to cytotoxic agents such as radiation. Various abnormalities in the hair and hair follicles have been reported in the past. Changes in the number of cells in the newly forming hair cortex have been shown in the mouse to...

journal_title：Radiation and environmental biophysics

authors： Potten CS,Burt PA,Roberts SA,Deshpande NA,Williams PC,Ramsden J

更新日期：1996-05-01 00:00:00

abstract：:The Auger electron emitter 123I was examined in the form of 4-[123I]iodoantipyrine and as [123I]NaI for its effectiveness in killing cells of different sensitivity to photon irradiation. Micronucleus assays showed that 4-[123I]iodoantipyrine is 2-3 times more effective in cell inactivation than [123I]NaI. This can be ...

journal_title：Radiation and environmental biophysics

authors： Smit BS,Slabbert JP,Reinecke SA,Böhm L

更新日期：2001-03-01 00:00:00

abstract：:Stem cells surviving radiation injury may carry defects which contribute to long-term effects. The ratio of 125-iododeoxyuridine (IUdR) uptake into spleens of lethally irradiated recipient mice between day 3 and day 5 after cell transfusion revealed reduced proliferative ability (PF) of spleen seeding cells in paralle...

journal_title：Radiation and environmental biophysics

authors： von Wangenheim KH,Peterson HP,Feinendegen LE

更新日期：1986-01-01 00:00:00

abstract：:Responses of the S/S variant of the L5178Y murine leukemic lymphoblast, the photoreceptor cell of the rabbit retina and the lenticular epithelium of the rabbit to heavy ions (20Ne, 28Si, 40Ar and 56Fe) are described and discussed primarily from the standpoint of the need for a comprehensive theory of cellular radiosen...

journal_title：Radiation and environmental biophysics

authors： Lett JT,Cox AB,Bergtold DS

更新日期：1986-01-01 00:00:00

abstract：:Many experimental studies are carried out to compare biological effectiveness of high dose rate (HDR) with that of low dose rate (LDR). The rational for this is the uncertainty regarding the value of the dose rate effectiveness factor (DREF) used in radiological protection. While a LDR is defined as 0.1 mGy/min or low...

journal_title：Radiation and environmental biophysics

authors： Olofsson D,Cheng L,Fernández RB,Płódowska M,Riego ML,Akuwudike P,Lisowska H,Lundholm L,Wojcik A

更新日期：2020-08-01 00:00:00

abstract：:Model experiments with two structurally different proteins (alcohol dehydrogenase and salmine) show that glycine, alanine, and tyrosine are by far more frequently involved in photochemically induced cross-link formations with DNA than is cysteine. The yields for cross-link formation of thymidine with salmine (cysteine...

journal_title：Radiation and environmental biophysics

authors： Toth B,Dose K

更新日期：1976-07-30 00:00:00

abstract：:The work reported here was originally motivated by a discussion of Monte Carlo computer codes for electron transport in water given in Report No. 130 by the National Council on Radiation Protection and Measurements (NCRP). It was pointed out (correctly) that a published depth-dose distribution calculated by the Oak Ri...

journal_title：Radiation and environmental biophysics

authors： Semenenko VA,Turner JE,Borak TB

更新日期：2003-10-01 00:00:00

abstract：:Thorough studies of 28 water bodies, predominantly lakes from the younger moraine area of Schleswig-Holstein, Northern Germany but also some peat bog waters in Niedersachsen, Northern Germany and lake Balaton in Hungary, showed the presence of at least six redox systems: NO3-/NO2-; NO3-/NH4+; NO2-/NH4+; So/HS-; So/H2S...

journal_title：Radiation and environmental biophysics

authors： David R

更新日期：1986-01-01 00:00:00

abstract：:Quantitative cancer incidence data exist for various laboratory animal models, but little of this information is usable for estimating human risks, primarily because of uncertainties about possible mechanistic differences among species. Acceptance and utilization of animal data for human risk assessment will require a...

journal_title：Radiation and environmental biophysics

authors： Burns FJ,Tang MS,Frenkel K,Nádas A,Wu F,Uddin A,Zhang R

更新日期：2007-06-01 00:00:00

abstract：:A human total-body counter was designed and built with two 20 X 10 cm NaI (Tl) crystals suspended over an "isoresponse surface" upon which the subject reclines. This surface is curved from head to knee and from left to right, so that a gamma-ray emitting object is detected with equal efficiency when placed anywhere up...

journal_title：Radiation and environmental biophysics

authors： Lloyd RD,Mays CW,Taysum DH

更新日期：1979-04-30 00:00:00

abstract：:The potential mechanisms underlying the increase in serum iron concentration in gamma-irradiated mice were studied. The gamma irradiation dose used was 4 Gy, and cobalt-60 ((60)Co) source was used for the irradiation. The dose rate was 0.25 Gy/min. In the serum of irradiated mice, the concentration of ferrous ions dec...

journal_title：Radiation and environmental biophysics

authors： Xie LH,Zhang XH,Hu XD,Min XY,Zhou QF,Zhang HQ

更新日期：2016-03-01 00:00:00

abstract：:A method which allows growth of normal human tissue to be studied in vitro is used to investigate possible interactive effects of radiation and environmentally important carcinogens on oesophageal and urothelial cell growth. Carcinogens chosen were selected for their known or suspected effect on the oesophageal mucosa...

journal_title：Radiation and environmental biophysics

authors： Mothersill C,Cusack A,Seymour CB

更新日期：1989-01-01 00:00:00

abstract：:For studies on cell membranes, mice were exposed to mixed neutron + gamma reactor-radiation in the range of total doses from 0.5 to 4.5 Gy. Changes in functional activity of plasma membranes of erythrocytes, platelets, and lymphocytes were followed by a lectin-binding technique at various intervals afterwards. The amo...

journal_title：Radiation and environmental biophysics

authors： Kubasova T,Antal S,Somosy Z,Köteles GJ

更新日期：1984-01-01 00:00:00

abstract：:The aim of this study was to detect membrane fluidity modifications in blood lymphocytes that had been exposed to gamma-radiation, at a graded series of depths from the surface to the centre of the membrane bilayer and as a function of cell viability. A time course was performed to verify the contribution of the membr...

journal_title：Radiation and environmental biophysics

authors： Vincent-Genod L,Benderitter M,Voisin P

更新日期：2001-09-01 00:00:00

abstract：:The objective of the present work is to apply the plasma clearance parameters to strontium, previously determined in our laboratory, to improve the biokinetic and dosimetric models of strontium-90 ((90)Sr) used in radiological protection; and also to apply this data for the estimation of the radiation doses from stron...

journal_title：Radiation and environmental biophysics

authors： Li WB,Höllriegl V,Roth P,Oeh U

更新日期：2008-04-01 00:00:00

abstract：:Computational models of human anatomy are mathematical representations of human anatomy designed to be used in dosimetry calculations. They have been used in dosimetry calculations for radiography, radiotherapy, nuclear medicine, radiation protection and to investigate the effects of low frequency electromagnetic fiel...

journal_title：Radiation and environmental biophysics

authors： Caon M

更新日期：2004-02-01 00:00:00

abstract：:Total body Irradiation (TBI) is often used for conditioning, prior to bone marrow transplantation. Doses of 8-14 Gy in 1-8 fractions over 1-4 days are administered using low dose rate external beam radiotherapy (EBRT). When necessary, consolidation EBRT using conventional doses, fractionation and dose rate is given. T...

journal_title：Radiation and environmental biophysics

authors： Nevelsky A,Bar-Deroma R,Kuten A

更新日期：2009-11-01 00:00:00

abstract：:Radiocaesium absorption and retention in reindeer (Rangifer tarandus) calves was compared in groups fed diets containing different proportions of lichen and concentrates, and different chemical forms of radiocaesium ((134)CsCl in solution or fallout from the Chernobyl accident). Daily intakes of fallout radiocaesium w...

journal_title：Radiation and environmental biophysics

authors： Skuterud L,Pedersen Ø,Staaland H,Røed KH,Salbu B,Liken A,Hove K

更新日期：2004-12-01 00:00:00

abstract：:Time-dependent yields of the most important products of water radiolysis E(aq)(-), (*)OH, H(*), H(3)O(+), H(2), OH(-) and H(2)O(2) have been calculated for (60)Co-photons, electrons, protons, helium- and carbon-ions incident onto water. G values have been evaluated for the interval from 1 ps to 1 mus after initial ene...

journal_title：Radiation and environmental biophysics

authors： Kreipl MS,Friedland W,Paretzke HG

更新日期：2009-02-01 00:00:00

abstract：:The effect of gamma radiation on red blood cells have been examined using a spin labeling method. For this purpose two spin labels were used to monitor membrane fluidity: methyl 5-doxylpalmitate (Met 5-DP) and methyl 12-doxylstearate (Met 12-DS). The irradiation of red cells with the doses of 200 and 500 Gy caused dec...

journal_title：Radiation and environmental biophysics

authors： Gwoździński K

更新日期：1991-01-01 00:00:00