Abstract:
:Two populations of thymic lymphocytes from eight-week-old mice were separated based on the light scatter intensity they generated while passing through a flow cell analyser. The two populations were subsequently studied morphologically and analysed for the relative amount of DNA present in each cell. Cells having a low light scatter intensity had a high nuclear:cytoplasmic ratio, a heterochromatic nucleus, and a proliferative index (S + G2 + M) of only 23%. Cells with a high light scatter intensity had a low nuclear:cytoplasmic ratio, dispersed chromatin, frequently a uropod with budding microvilli and a proliferative index of 71%. The low light scatter cells resemble small cortical thymocytes or lymphocytes from the thoracic duct described by others. The highest light scatter cells resemble medium lymphocytes shown by others to be proliferative.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Haar JL,Grogan WM,Collins JMdoi
10.1007/BF00234855subject
Has Abstractpub_date
1979-09-01 00:00:00pages
443-51issue
3eissn
0302-766Xissn
1432-0878journal_volume
200pub_type
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