Effects of streptomycin deprivation on enzyme synthesis in streptomycin-dependent Escherichia coli.

Abstract:

:During growth of streptomycin-dependent strains of Escherichia coli in the absence of streptomycin (deprived growth), both constitutive and inducible synthesis of beta-galactosidase were preferentially inhibited. A similar preferential inhibition of constitutive and derepressed synthesis of alkaline phosphatase was observed. Catabolite repression accounted for part, but not all, of the inhibition of the inducible beta-galactosidase synthesis. Serological experiments indicated that that part of the inhibition specificially associated with streptomycin deprivation was not a result of the production of altered beta-galactosidase. It is suggested that during deprived growth the ribosomes of streptomycin-dependent bacteria become impaired in their ability to translate certain messages.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Goodman RE,Spotts CR

doi

10.1128/JB.94.4.1154-1161.1967

subject

Has Abstract

pub_date

1967-10-01 00:00:00

pages

1154-61

issue

4

eissn

0021-9193

issn

1098-5530

journal_volume

94

pub_type

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